iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059588

Ensembl Protein ID

ENSMGAP00000013736.1

UniProt Accession

G1NK25; G1NK25_MELGA

Protein Name

Phosphoinositide phospholipase C

Gene Name

LOC100542272

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000013016.1	ENSMGAT00000014651.1	ENSMGAP00000013736.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-11	44.1	792	846

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekl 62
           +v++lydy+aq +deL++ k  +++ +  ++qd+gW++g  +  gk+ l fP+n+ve++
   Q: 792  TVKALYDYKAQREDELSFCKQAIIHNV--DKQDGGWWRG--DYGGKKQLwFPANYVEEI 846
           79************************9..9*********..676666655*******97 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MSMSRLNSVN GFLEDGRMEA GDIGRILRCL EMGTVLTLFY QKKSQRPERR TFQVKLETRQ 60
IIWSRTPEKV EGDIDIREIK EIRLGKNSRD FERYPEDARK LDFAMCFIIL YGMDFRLRTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCATGT CCAGGCTCAA CAGCGTCAAT GGCTTTTTGG AGGACGGCAG GATGGAGGCA 60
GGGGACATTG GAAGGATCCT CCGCTGCCTG GAGATGGGCA CCGTCCTCAC TTTATTCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer

Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005509--F:calcium ion binding
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0035556--P:intracellular signal transduction
GO:0009395--P:phospholipid catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003541	Anas platyrhynchos	98.35	0.00e+00	2510.00
IUUC-Cin-025520	Ciona intestinalis	49.01	0.00e+00	1144.00
IUUC-Fal-037454	Ficedula albicollis	97.97	0.00e+00	2560.00
IUUC-Gga-040211	Gallus gallus	99.52	0.00e+00	2497.00
IUUC-Lch-049812	Latimeria chalumnae	85.28	0.00e+00	1970.00
IUUC-Tni-120833	Tetraodon nigroviridis	78.75	0.00e+00	2057.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence