iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010602

Ensembl Protein ID

ENSAMXP00000007227.1

UniProt Accession

W5KI15; W5KI15_ASTMX

Genbank Protein ID

ENSAMXP00000007227

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01109943

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000007033.1	ENSAMXT00000007227.1	ENSAMXP00000007227.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-32	109.6	120	157
UBD/Beta-Prp	1.90e-50	171.9	223	482

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  + +++ +GsdD+ +k+W +++g+ll
   Q: 120  GHLSSVYCVAFdRTgRRIFTGSDDCLVKIWATDDGRLL 157
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkl........lrslsgheae......vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghed 95
           ++la++++dg++  w++ + ++        +   +           +++++fs  g +l+tg++D++++v+    + +  ++ l  h+d
   Q: 223  RYLASTGADGMVCFWQWNNLTMkfidrpvkFT--E----RsrpgvqISCCSFSTGGMFLATGGTDHVLRVYylGSEVPIKLSDLDSHTD 305
           599*********99999985556666653322..2....133345599***********************55555667778899**** PP
   S: 96   svlslsfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl 166
           +v +++f+ ++   ++vsGs+d t+r+w+ +++++ +                  ++ ++ vv++v+++ +++ ++++  +  +++W++
   Q: 306  KVNAVQFCNNSdcLRFVSGSRDGTARIWQYQQQEWKSItldmstklpgstaasgEDKSTKLVVTMVAWDRSDRTVITAVSNFLLKVWNS 394
           *********6625689****************9999989***********99999999999**************************** PP
   S: 167  ktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
            +g+ll+ l+g h+d vy l+ ++   + ++s+++dg + +wdl++g+ +r + +         v + +fs ++++++++ s+g + i+
   Q: 395  TNGQLLHILSG-HDDEVYVLEAHPFDwRIMLSAGHDGNIYIWDLSKGTKIRNYFNMIegqghGAVFDCKFSADGQHFACTDSHGHLLIF 482
           **********9.*********66655599********************8888775545555667778888888888888888887775 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MQVALNRHIP ADYLLRVCNQ VCPLVDKHVP PSVPGVRSLL GTGRQSLLRT AKSCAYTVWT 60
GSSVAALHRG RPPEPPVNFG KSPNVVSVMG ARKITGAGRF GHVLPSCTYQ HMKMHRRILG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAGAAATGG CTAAAAGAAC AAAAAAGATG CAGAGCTTTC AGACCTCAAA TAATGCAAAG 60
AAGACAAGTT CATATTCATT AAGTTTTAAG AGCTCAGAAA TCAATACTTG GTGGAATAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	64.88	0.00e+00	1862.00
IUUC-Apl-004016	Anas platyrhynchos	65.70	0.00e+00	1795.00
IUUC-Aca-004722	Anolis carolinensis	69.48	0.00e+00	1735.00
IUUC-Bdi-014797	Brachypodium distachyon	33.00	3.00e-51	197.00
IUUC-Cfa-020963	Canis familiaris	68.03	0.00e+00	1855.00
IUUC-Csa-023166	Chlorocebus sabaeus	67.83	0.00e+00	1852.00
IUUC-Cin-025553	Ciona intestinalis	39.27	5.00e-107	382.00
IUUC-Dre-028508	Danio rerio	76.70	0.00e+00	2212.00
IUUC-Dno-030070	Dasypus novemcinctus	66.31	0.00e+00	1771.00
IUUC-Dor-030195	Dipodomys ordii	59.01	0.00e+00	900.00
IUUC-Ete-032650	Echinops telfairi	70.52	0.00e+00	986.00
IUUC-Eeu-034871	Erinaceus europaeus	62.31	0.00e+00	907.00
IUUC-Fca-036099	Felis catus	67.79	0.00e+00	1852.00
IUUC-Fal-037246	Ficedula albicollis	69.02	0.00e+00	1894.00
IUUC-Gmo-039116	Gadus morhua	72.33	0.00e+00	628.00
IUUC-Gga-041097	Gallus gallus	69.43	0.00e+00	1913.00
IUUC-Gac-042435	Gasterosteus aculeatus	70.34	0.00e+00	1917.00
IUUC-Hsa-045666	Homo sapiens	68.03	0.00e+00	1859.00
IUUC-Hvu-047706	Hordeum vulgare	33.14	3.00e-34	139.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	60.14	0.00e+00	681.00
IUUC-Lch-050646	Latimeria chalumnae	60.73	0.00e+00	1699.00
IUUC-Loc-051802	Lepisosteus oculatus	71.15	0.00e+00	2049.00
IUUC-Laf-053942	Loxodonta africana	67.81	0.00e+00	1882.00
IUUC-Mcc-054645	Macaca mulatta	67.91	0.00e+00	1856.00
IUUC-Meu-056321	Macropus eugenii	60.25	0.00e+00	876.00
IUUC-Mga-060063	Meleagris gallopavo	68.27	0.00e+00	1899.00
IUUC-Mmr-061262	Microcebus murinus	64.75	0.00e+00	1880.00
IUUC-Mmu-063163	Mus musculus	68.01	0.00e+00	1861.00
IUUC-Mpu-066628	Mustela putorius furo	64.77	0.00e+00	1854.00
IUUC-Mlu-068082	Myotis lucifugus	64.44	0.00e+00	1821.00
IUUC-Nle-069609	Nomascus leucogenys	67.76	0.00e+00	1856.00
IUUC-Opr-070971	Ochotona princeps	59.01	3.00e-164	573.00
IUUC-Ont-071589	Oreochromis niloticus	68.96	0.00e+00	1927.00
IUUC-Ocu-074122	Oryctolagus cuniculus	65.69	0.00e+00	1368.00
IUUC-Oin-079669	Oryza indica	32.98	4.00e-51	196.00
IUUC-Olo-080755	Oryza longistaminata	32.91	4.00e-52	200.00
IUUC-Oni-082991	Oryza nivara	27.54	9.00e-30	126.00
IUUC-Ola-086580	Oryzias latipes	72.17	0.00e+00	1962.00
IUUC-Oga-089053	Otolemur garnettii	64.42	0.00e+00	1860.00
IUUC-Oar-090042	Ovis aries	64.42	0.00e+00	1857.00
IUUC-Ptr-091268	Pan troglodytes	67.83	0.00e+00	1853.00
IUUC-Pan-092376	Papio anubis	67.91	0.00e+00	1857.00
IUUC-Psi-093408	Pelodiscus sinensis	67.48	0.00e+00	1898.00
IUUC-Pfo-096515	Poecilia formosa	69.01	0.00e+00	1884.00
IUUC-Pab-097672	Pongo abelii	66.19	0.00e+00	1811.00
IUUC-Pca-101128	Procavia capensis	65.59	0.00e+00	993.00
IUUC-Pva-102512	Pteropus vampyrus	70.27	0.00e+00	1619.00
IUUC-Rno-105797	Rattus norvegicus	67.58	0.00e+00	1853.00
IUUC-Sha-107061	Sarcophilus harrisii	63.07	0.00e+00	1736.00
IUUC-Sar-113004	Sorex araneus	77.35	0.00e+00	805.00
IUUC-Tgu-117254	Taeniopygia guttata	67.81	0.00e+00	1880.00
IUUC-Tru-118186	Takifugu rubripes	70.64	0.00e+00	1887.00
IUUC-Tsy-119003	Tarsius syrichta	61.11	0.00e+00	1684.00
IUUC-Tni-120110	Tetraodon nigroviridis	70.53	0.00e+00	1863.00
IUUC-Tbe-127479	Tupaia belangeri	54.48	0.00e+00	792.00
IUUC-Ttr-129265	Tursiops truncatus	68.03	0.00e+00	1847.00
IUUC-Vpa-130160	Vicugna pacos	61.74	0.00e+00	1005.00
IUUC-Xtr-132717	Xenopus tropicalis	60.33	0.00e+00	1658.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence