iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000002561.1	ENSTGUT00000002666.1	ENSTGUP00000002638.1
ENSTGUG00000002561.1	ENSTGUT00000002668.1	ENSTGUP00000002640.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-29	99.2	118	156
UBD/Beta-Prp	1.10e-52	178.8	221	479

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           gH +sv+c+af  s++++ +GsdD+ +k+W +++g+ll 
   Q: 118  GHLSSVYCIAFdrSGRRIFTGSDDCLVKIWATDDGRLLS 156
           8**********96669******************99875 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkl........lrslsgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsls 101
           ++l+++++dgti  w+++  ++        +++ s    ++++ +fs+ g +++tgs+D++i+++    ++++ +  l+ h+d+v++++
   Q: 221  RYLTSTGADGTICFWQWHASTMkfkdrpvkFAERSRPGVQISCSSFSSGGMFIATGSTDHVIRIYylGSESPEKMAELESHTDKVVAVQ 309
           79**************9997766677764444444444449************************88888******************* PP
   S: 102  fspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkll 172
           f+ +g   ++vsGs+d t+r+w+ ++  + +                  +++++  v++v+++  +  ++++ ++  +++W+++tg+ll
   Q: 310  FCNNGdsLRFVSGSRDGTARIWHYHQHDWKSLvldmatkmtgnnvasgEDKVTKLKVTMVAWDRYDATVITAVNNFLLKVWNSSTGQLL 398
           ***8832468*************999988877899*********8888888888899******************************** PP
   S: 173  rtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiri 248
           + l+g h+d v  l+   fd+  + ++s+++dg + +wd+ +g+ +r + +         v + +fsp++++++++ s+g + +
   Q: 399  HSLSG-HDDEVFVLEahpFDQ--RIVLSAGHDGNIFVWDIDKGTKIRNYFNMIegqghGAVFDCKFSPDGQHFACTDSHGHLLL 479
           ****9.*********554544..8999******************988877554555577778899999999999999988766 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

VAVNAHIPPD YLLRICERLG PLLDKEIPQS VLGVQTLLGV GRQSLLRAAK DFRHTLWKGS 60
AFAALHRGRP PELPVNYGKP PNVVHILSAR QLTGCGRFSH LFPTSTYQHM KMHKRILGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGCTGTCA ATGCACACAT CCCTCCAGAT TATCTTCTTA GGATCTGTGA GAGACTTGGA 60
CCCCTCCTGG ACAAGGAAAT CCCTCAGAGT GTTCTGGGGG TGCAGACTTT GCTGGGTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	82.83	0.00e+00	2442.00
IUUC-Apl-004016	Anas platyrhynchos	90.28	0.00e+00	2491.00
IUUC-Aca-004722	Anolis carolinensis	86.55	0.00e+00	2367.00
IUUC-Ame-010602	Astyanax mexicanus	67.34	0.00e+00	1858.00
IUUC-Bta-013198	Bos taurus	81.86	0.00e+00	2305.00
IUUC-Cfa-020963	Canis familiaris	82.80	0.00e+00	2435.00
IUUC-Cpo-022448	Cavia porcellus	77.97	0.00e+00	2301.00
IUUC-Csa-023166	Chlorocebus sabaeus	82.30	0.00e+00	2420.00
IUUC-Cin-025553	Ciona intestinalis	40.26	6.00e-115	407.00
IUUC-Dre-028508	Danio rerio	66.30	0.00e+00	1816.00
IUUC-Dno-030070	Dasypus novemcinctus	80.69	0.00e+00	2340.00
IUUC-Ete-032650	Echinops telfairi	80.80	0.00e+00	1592.00
IUUC-Eca-033953	Equus caballus	83.16	0.00e+00	2280.00
IUUC-Eeu-034871	Erinaceus europaeus	74.07	0.00e+00	1125.00
IUUC-Fca-036099	Felis catus	82.65	0.00e+00	2432.00
IUUC-Fal-037246	Ficedula albicollis	97.76	0.00e+00	2822.00
IUUC-Gga-041097	Gallus gallus	94.35	0.00e+00	2773.00
IUUC-Gac-042435	Gasterosteus aculeatus	65.58	0.00e+00	1774.00
IUUC-Hsa-045666	Homo sapiens	82.30	0.00e+00	2424.00
IUUC-Loc-051802	Lepisosteus oculatus	71.51	0.00e+00	2055.00
IUUC-Laf-053942	Loxodonta africana	82.17	0.00e+00	2467.00
IUUC-Mcc-054645	Macaca mulatta	82.36	0.00e+00	2424.00
IUUC-Meu-056321	Macropus eugenii	73.29	0.00e+00	1057.00
IUUC-Mga-060063	Meleagris gallopavo	94.61	0.00e+00	2786.00
IUUC-Mmr-061262	Microcebus murinus	82.75	0.00e+00	2452.00
IUUC-Mdo-062320	Monodelphis domestica	74.76	0.00e+00	2133.00
IUUC-Mmu-063163	Mus musculus	82.13	0.00e+00	2413.00
IUUC-Mpu-066628	Mustela putorius furo	82.67	0.00e+00	2441.00
IUUC-Mlu-068082	Myotis lucifugus	82.26	0.00e+00	2383.00
IUUC-Nle-069609	Nomascus leucogenys	82.36	0.00e+00	2430.00
IUUC-Ont-071589	Oreochromis niloticus	63.79	0.00e+00	1759.00
IUUC-Ocu-074122	Oryctolagus cuniculus	81.83	0.00e+00	1813.00
IUUC-Ogu-078641	Oryza glumaepatula	26.10	4.00e-30	127.00
IUUC-Ola-086580	Oryzias latipes	66.33	0.00e+00	1798.00
IUUC-Oga-089053	Otolemur garnettii	82.34	0.00e+00	2435.00
IUUC-Oar-090042	Ovis aries	82.53	0.00e+00	2434.00
IUUC-Ptr-091268	Pan troglodytes	82.23	0.00e+00	2419.00
IUUC-Pan-092376	Papio anubis	82.36	0.00e+00	2424.00
IUUC-Psi-093408	Pelodiscus sinensis	90.46	0.00e+00	2711.00
IUUC-Pfo-096515	Poecilia formosa	66.00	0.00e+00	1711.00
IUUC-Pab-097672	Pongo abelii	80.33	0.00e+00	2387.00
IUUC-Pva-102512	Pteropus vampyrus	86.54	0.00e+00	2023.00
IUUC-Rno-105797	Rattus norvegicus	81.84	0.00e+00	2410.00
IUUC-Sha-107061	Sarcophilus harrisii	73.23	0.00e+00	2353.00
IUUC-Sar-113004	Sorex araneus	67.63	0.00e+00	1188.00
IUUC-Tru-118186	Takifugu rubripes	66.62	0.00e+00	1754.00
IUUC-Tsy-119003	Tarsius syrichta	78.04	0.00e+00	2249.00
IUUC-Tni-120110	Tetraodon nigroviridis	66.55	0.00e+00	1731.00
IUUC-Ttr-129265	Tursiops truncatus	82.12	0.00e+00	2370.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence