iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020305

Ensembl Protein ID

ENSCAFP00000007214.3

UniProt Accession

E2RM32; E2RM32_CANLF

Genbank Protein ID

ENSCAFP00000007214

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03006297

Gene Name

LLGL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000004816.3	ENSCAFT00000007782.3	ENSCAFP00000007214.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.00e-08	33.6	427	451

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 8    claf..sd.tllvsGsdDgtikvWD 29
           +la   +  +ll++G  Dgt++ WD
   Q: 427  SLAPapPQrDLLLTGHEDGTVRFWD 451
           44446656689************** PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MRRFLRPGHD PARERLKRDL FQFNKTVEHG FPHQPSALGY SLSLRILAIG TRSGAVKLYG 60
APGVEFMGLH RENNAVVQIH FLPGQCQLVT LLDDNSLHLW RLTVKGGVSE LQEDESFTLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCTCCAC ACTCAGCACC ATGCGGCGGT TCCTGAGGCC AGGGCATGAC CCTGCGCGGG 60
AGAGGCTCAA GCGGGACCTC TTCCAGTTTA ACAAGGTAAG AGGGGCCGCA CTGTGTCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000664--Lethal2_giant
IPR013577--LLGL2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2

Pfam

PF08366--LLGL
PF00400--WD40

PRINTS

PR00962--LETHAL2GIANT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0005096--F:GTPase activator activity
GO:0017137--F:Rab GTPase binding
GO:0032878--P:regulation of establishment or maintenance of cell polarity
GO:0017157--P:regulation of exocytosis
GO:0050708--P:regulation of protein secretion

KEGG

cfa:609568

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002413	Ailuropoda melanoleuca	95.40	0.00e+00	1886.00
IUUC-Apl-003619	Anas platyrhynchos	76.68	0.00e+00	1566.00
IUUC-Bta-013249	Bos taurus	93.05	0.00e+00	1890.00
IUUC-Cpo-021354	Cavia porcellus	89.19	0.00e+00	1788.00
IUUC-Csa-024027	Chlorocebus sabaeus	92.37	0.00e+00	1820.00
IUUC-Cin-025693	Ciona intestinalis	45.55	0.00e+00	745.00
IUUC-Dno-028910	Dasypus novemcinctus	88.30	0.00e+00	1677.00
IUUC-Dor-030976	Dipodomys ordii	87.62	0.00e+00	1748.00
IUUC-Ete-032938	Echinops telfairi	79.30	0.00e+00	920.00
IUUC-Eeu-035274	Erinaceus europaeus	91.04	0.00e+00	1685.00
IUUC-Fca-036585	Felis catus	94.13	0.00e+00	1843.00
IUUC-Fal-037603	Ficedula albicollis	78.58	0.00e+00	1593.00
IUUC-Gga-040222	Gallus gallus	75.63	0.00e+00	1562.00
IUUC-Ggo-045203	Gorilla gorilla	91.78	0.00e+00	1803.00
IUUC-Hsa-045870	Homo sapiens	92.07	0.00e+00	1842.00
IUUC-Lch-049973	Latimeria chalumnae	71.07	0.00e+00	1414.00
IUUC-Laf-053899	Loxodonta africana	89.21	0.00e+00	1810.00
IUUC-Mcc-055790	Macaca mulatta	92.17	0.00e+00	1810.00
IUUC-Mga-059850	Meleagris gallopavo	74.53	0.00e+00	1521.00
IUUC-Mmr-060930	Microcebus murinus	88.74	0.00e+00	1743.00
IUUC-Mdo-062588	Monodelphis domestica	83.76	0.00e+00	1711.00
IUUC-Mmu-064054	Mus musculus	88.01	0.00e+00	1769.00
IUUC-Mpu-065729	Mustela putorius furo	94.03	0.00e+00	1885.00
IUUC-Mlu-066984	Myotis lucifugus	92.02	0.00e+00	1853.00
IUUC-Nle-069136	Nomascus leucogenys	90.69	0.00e+00	1746.00
IUUC-Oan-073438	Ornithorhynchus anatinus	74.13	0.00e+00	1290.00
IUUC-Ocu-074863	Oryctolagus cuniculus	89.93	0.00e+00	1717.00
IUUC-Ola-086437	Oryzias latipes	66.47	0.00e+00	1212.00
IUUC-Oga-088270	Otolemur garnettii	91.29	0.00e+00	1827.00
IUUC-Ptr-091452	Pan troglodytes	92.90	0.00e+00	1773.00
IUUC-Pan-092654	Papio anubis	92.66	0.00e+00	1825.00
IUUC-Psi-093341	Pelodiscus sinensis	78.77	0.00e+00	1603.00
IUUC-Pva-102373	Pteropus vampyrus	93.54	0.00e+00	1856.00
IUUC-Rno-104988	Rattus norvegicus	89.38	0.00e+00	1790.00
IUUC-Sha-106592	Sarcophilus harrisii	79.70	0.00e+00	1569.00
IUUC-Tgu-117381	Taeniopygia guttata	78.12	0.00e+00	1557.00
IUUC-Tbe-127984	Tupaia belangeri	85.39	0.00e+00	905.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence