iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089510

Ensembl Protein ID

ENSOARP00000020109.1

UniProt Accession

W5QBL2; W5QBL2_SHEEP

Genbank Protein ID

ENSOARP00000020109

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01089750

Gene Name

CUL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000018724.1	ENSOART00000020387.1	ENSOARP00000020109.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	9.80e-226	751.4	24	668

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk...........................vgaklYkklkevleefikqvkkkveesed 62
           lr++++++++++s+ k++y+elyt+vyn+c+s                            vg +lYk+lke+l+++++++ k+ e+ +d
   Q: 24   LRAGIQQVYTRQSMaKSRYMELYTHVYNYCTSVhqsnqargagvppskskkgqtpggaqfVGLELYKRLKEFLKNYLTNLLKDGEDLMD 112
           7899***************************9999****************************************************** PP
   S: 63   eqlLktynreWekfreqlkvlrkifayldrtyvkk.............skkvsevrkLaldlwrkeivedikkrllelllklieaeRkg 138
           e++Lk+y+++We++r ++kvl+ i+ayl+r++v+              +k ++e+++Lal +wr++++++++k++++++lklie+eR+g
   Q: 113  ESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVHGecdegrkglyeigRKGLYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNG 201
           *********************************9999999999999999999************************************* PP
   S: 139  eavdrrllsgvveslveLslnk.........laiykesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraarylees 218
           e++++rl+sgvv+s+veL+ln+         l++ykesFE +fl  t++fy++es+eflq+n v+eY+kk+earl ee++r++ yl+es
   Q: 202  ETINTRLISGVVQSYVELGLNEddafakgptLTVYKESFECQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHES 290
           ***************************************************************************************** PP
   S: 219  tetkLlevvekeliakhlesllaelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaalt..aeekekdpkkyVerll 305
           t+++L++++e++li+khle +++e+++ll+ +k+edl+rmy+L+sr+++gl el k le+hi++qg+aa++   e++ +dpk+yV+++l
   Q: 291  TQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEkcGEAALNDPKMYVQTVL 379
           ***********************************************************************9999999*********** PP
   S: 306  elknklqklvseaFnndakFlkaldkafetfvnknsvlka....akspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekd 390
           ++++k++ lv++aFnnda F+ aldka+ +f+n+n+v+k+    +kspEllAry+D+lL+kssk+++e+ele++l++v++vfkyi++kd
   Q: 380  DVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMaqssSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKD 468
           ***************************************************************************************** PP
   S: 391  vFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeekenteesesvelsvlvLsagaWpta 479
           vF+k+Y+k+LakRL++++sas++aE+s+i+kLk++cg+e+tskL+rMfqd+ vS+dln+qFk++ +n+ e  ++++s++vLs+g+Wp++
   Q: 469  VFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNS-EPLDLDFSIQVLSSGSWPFQ 556
           **************************************************************777776.99****************** PP
   S: 480  setekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeL 568
           ++   ++LP+ele+++++f++fY ++hsgRkL+W+++l+++el ++++k++y+lq+stfQma+LL++n+++++ v++l+++t+++++ L
   Q: 557  QSCT-FALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDAYAVQQLTDSTQIKMDIL 644
           7755.************************************************************************************ PP
   S: 569  rrtlqsLvsskkqvlkkepeskeiee 594
            ++lq L++sk  +l  e+e+++++e
   Q: 645  AQVLQILLKSK--LLVLEDENANVDE 668
           **********9..5555555555544 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MSSNRSQNPH GLKQIGLDQI WDDLRAGIQQ VYTRQSMAKS RYMELYTHVY NYCTSVHQSN 60
QARGAGVPPS KSKKGQTPGG AQFVGLELYK RLKEFLKNYL TNLLKDGEDL MDESVLKFYT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCATCCA ACCGGAGTCA GAACCCCCAC GGACTGAAGC AGATTGGCCT CGACCAGATC 60
TGGGACGACC TCAGAGCTGG CATCCAGCAA GTGTACACCA GACAGAGCAT GGCCAAGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002277	Ailuropoda melanoleuca	98.29	0.00e+00	1507.00
IUUC-Apl-003503	Anas platyrhynchos	97.41	0.00e+00	1254.00
IUUC-Aca-005030	Anolis carolinensis	85.97	0.00e+00	1211.00
IUUC-Ago-007977	Ashbya gossypii	31.14	6.00e-109	388.00
IUUC-Acl-008190	Aspergillus clavatus	48.41	0.00e+00	632.00
IUUC-Afl-008542	Aspergillus flavus	48.95	1.00e-152	533.00
IUUC-Afu-009007	Aspergillus fumigatus	47.91	1.00e-176	613.00
IUUC-Ani-009290	Aspergillus nidulans	46.04	0.00e+00	648.00
IUUC-Ang-009600	Aspergillus niger	48.08	0.00e+00	627.00
IUUC-Aor-009978	Aspergillus oryzae	46.74	1.00e-162	566.00
IUUC-Ate-010584	Aspergillus terreus	47.66	0.00e+00	649.00
IUUC-Ame-011861	Astyanax mexicanus	93.62	0.00e+00	1389.00
IUUC-Bgr-012209	Blumeria graminis	46.78	2.00e-180	625.00
IUUC-Bta-012878	Bos taurus	98.42	0.00e+00	1511.00
IUUC-Bci-013941	Botrytis cinerea	46.62	0.00e+00	668.00
IUUC-Cel-018294	Caenorhabditis elegans	44.99	0.00e+00	646.00
IUUC-Cja-018965	Callithrix jacchus	93.15	0.00e+00	1422.00
IUUC-Cfa-020671	Canis familiaris	98.42	0.00e+00	1511.00
IUUC-Cpo-021762	Cavia porcellus	98.02	0.00e+00	1507.00
IUUC-Csa-023873	Chlorocebus sabaeus	98.15	0.00e+00	1507.00
IUUC-Cho-024978	Choloepus hoffmanni	99.50	9.00e-116	410.00
IUUC-Cin-025547	Ciona intestinalis	70.85	0.00e+00	1060.00
IUUC-Csv-026083	Ciona savignyi	70.27	0.00e+00	1103.00
IUUC-Cgl-026452	Colletotrichum gloeosporioides	46.95	0.00e+00	638.00
IUUC-Cne-026919	Cryptococcus neoformans	41.53	4.00e-168	584.00
IUUC-Dre-027875	Danio rerio	94.20	0.00e+00	1410.00
IUUC-Dno-028931	Dasypus novemcinctus	98.02	0.00e+00	1502.00
IUUC-Dor-030846	Dipodomys ordii	99.38	0.00e+00	960.00
IUUC-Dse-031472	Dothistroma septosporum	43.88	9.00e-164	570.00
IUUC-Dme-031793	Drosophila melanogaster	60.57	0.00e+00	883.00
IUUC-Ete-033112	Echinops telfairi	88.33	4.00e-152	531.00
IUUC-Eca-034309	Equus caballus	98.42	0.00e+00	1511.00
IUUC-Eeu-034450	Erinaceus europaeus	67.59	0.00e+00	699.00
IUUC-Fca-036330	Felis catus	94.89	0.00e+00	1447.00
IUUC-Fal-036899	Ficedula albicollis	98.10	0.00e+00	1360.00
IUUC-Fox-037705	Fusarium oxysporum	47.61	3.00e-176	612.00
IUUC-Fso-038367	Fusarium solani	48.03	0.00e+00	632.00
IUUC-Gmo-038708	Gadus morhua	92.65	0.00e+00	1400.00
IUUC-Ggr-039917	Gaeumannomyces graminis	46.37	0.00e+00	636.00
IUUC-Gga-041038	Gallus gallus	98.28	0.00e+00	1509.00
IUUC-Gac-041820	Gasterosteus aculeatus	93.18	0.00e+00	1451.00
IUUC-Ggo-045154	Gorilla gorilla	81.52	0.00e+00	1056.00
IUUC-Hsa-046034	Homo sapiens	98.15	0.00e+00	1507.00
IUUC-Itr-048285	Ictidomys tridecemlineatus	98.15	0.00e+00	1508.00
IUUC-Kpa-049231	Komagataella pastoris	36.92	3.00e-121	429.00
IUUC-Lch-049673	Latimeria chalumnae	96.97	0.00e+00	1489.00
IUUC-Loc-052490	Lepisosteus oculatus	96.05	0.00e+00	1450.00
IUUC-Lma-053191	Leptosphaeria maculans	46.89	7.00e-178	617.00
IUUC-Laf-054582	Loxodonta africana	98.02	0.00e+00	1507.00
IUUC-Mcc-055162	Macaca mulatta	97.23	0.00e+00	1488.00
IUUC-Meu-055904	Macropus eugenii	86.12	7.00e-143	501.00
IUUC-Mor-057035	Magnaporthe oryzae	45.77	5.00e-176	611.00
IUUC-Mpo-057555	Magnaporthe poae	46.37	0.00e+00	637.00
IUUC-Mla-059021	Melampsora laricipopulina	46.83	3.00e-176	612.00
IUUC-Mga-060078	Meleagris gallopavo	98.28	0.00e+00	1509.00
IUUC-Mvi-060519	Microbotryum violaceum	46.10	0.00e+00	629.00
IUUC-Mmr-061312	Microcebus murinus	98.15	0.00e+00	1507.00
IUUC-Mdo-062867	Monodelphis domestica	97.76	0.00e+00	1501.00
IUUC-Mmu-063336	Mus musculus	98.28	0.00e+00	1509.00
IUUC-Mpu-066400	Mustela putorius furo	98.25	0.00e+00	1361.00
IUUC-Mlu-067800	Myotis lucifugus	98.16	0.00e+00	1504.00
IUUC-Nfi-068384	Neosartorya fischeri	50.15	9.00e-177	613.00
IUUC-Ncr-068965	Neurospora crassa	46.75	0.00e+00	637.00
IUUC-Nle-069729	Nomascus leucogenys	98.15	0.00e+00	1507.00
IUUC-Ont-071729	Oreochromis niloticus	94.06	0.00e+00	1432.00
IUUC-Oan-073309	Ornithorhynchus anatinus	98.15	0.00e+00	1509.00
IUUC-Ocu-074661	Oryctolagus cuniculus	97.89	0.00e+00	1459.00
IUUC-Ola-087422	Oryzias latipes	92.63	0.00e+00	1429.00
IUUC-Oga-088130	Otolemur garnettii	98.15	0.00e+00	1507.00
IUUC-Ptr-090665	Pan troglodytes	98.15	0.00e+00	1507.00
IUUC-Pan-092218	Papio anubis	98.15	0.00e+00	1507.00
IUUC-Psi-093175	Pelodiscus sinensis	98.15	0.00e+00	1508.00
IUUC-Pma-094502	Petromyzon marinus	88.64	0.00e+00	1360.00
IUUC-Pno-095067	Phaeosphaeria nodorum	46.24	0.00e+00	647.00
IUUC-Pfo-096705	Poecilia formosa	93.93	0.00e+00	1469.00
IUUC-Pab-097578	Pongo abelii	98.15	0.00e+00	1507.00
IUUC-Pca-100242	Procavia capensis	84.36	0.00e+00	1130.00
IUUC-Pva-102155	Pteropus vampyrus	90.33	0.00e+00	1296.00
IUUC-Pgr-103297	Puccinia graminis	45.17	0.00e+00	629.00
IUUC-Ptt-103706	Puccinia triticina	44.39	4.00e-89	323.00
IUUC-Pte-104257	Pyrenophora teres	47.16	0.00e+00	648.00
IUUC-Pyt-104795	Pyrenophora triticirepentis	47.23	0.00e+00	648.00
IUUC-Rno-105939	Rattus norvegicus	98.28	0.00e+00	1509.00
IUUC-Sce-106293	Saccharomyces cerevisiae	30.66	2.00e-106	380.00
IUUC-Sha-106949	Sarcophilus harrisii	98.15	0.00e+00	1508.00
IUUC-Sja-107737	Schizosaccharomyces japonicus	41.41	2.00e-145	509.00
IUUC-Spo-108280	Schizosaccharomyces pombe	40.26	6.00e-152	531.00
IUUC-Sre-114984	Sporisorium reilianum	44.22	1.00e-165	577.00
IUUC-Ssc-115829	Sus scrofa	97.77	0.00e+00	1494.00
IUUC-Tgu-116950	Taeniopygia guttata	98.28	0.00e+00	1509.00
IUUC-Tru-118558	Takifugu rubripes	93.54	0.00e+00	1444.00
IUUC-Tsy-118934	Tarsius syrichta	95.12	0.00e+00	726.00
IUUC-Tni-120460	Tetraodon nigroviridis	93.40	0.00e+00	1450.00
IUUC-Tre-122223	Trichoderma reesei	48.33	1.00e-171	596.00
IUUC-Tvi-122539	Trichoderma virens	43.26	4.00e-160	558.00
IUUC-Tme-126926	Tuber melanosporum	46.03	0.00e+00	643.00
IUUC-Tbe-127369	Tupaia belangeri	97.48	5.00e-172	597.00
IUUC-Ttr-129022	Tursiops truncatus	93.89	0.00e+00	1085.00
IUUC-Uma-129341	Ustilago maydis	44.40	8.00e-157	547.00
IUUC-Vda-129857	Verticillium dahliae	46.13	3.00e-174	605.00
IUUC-Vpa-130166	Vicugna pacos	91.89	0.00e+00	1209.00
IUUC-Xtr-131818	Xenopus tropicalis	97.36	0.00e+00	1491.00
IUUC-Xma-134206	Xiphophorus maculatus	93.93	0.00e+00	1427.00
IUUC-Yli-134486	Yarrowia lipolytica	38.77	3.00e-144	505.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence