iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118483

Ensembl Protein ID

ENSTRUP00000012613.1

UniProt Accession

H2SJN0; H2SJN0_TAKRU

Protein Name

Uncharacterized protein

Gene Name

arhgef38; ARHGEF38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005258.1	ENSTRUT00000012671.1	ENSTRUP00000012610.1
ENSTRUG00000005258.1	ENSTRUT00000012672.1	ENSTRUP00000012611.1
ENSTRUG00000005258.1	ENSTRUT00000012673.1	ENSTRUP00000012612.1
ENSTRUG00000005258.1	ENSTRUT00000012674.1	ENSTRUP00000012613.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-10	41.6	453	509

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvek 61
            + + y ++a +d eLtl++   v+++  ++   +++W+ +  e +g+rG +P+n+  k
   Q: 453  PFYAVYAFQARSDQELTLQEYQHVRILqfSDLGGNKDWWLA--ECNGQRGYVPANYLGK 509
           56799**********************99999*******99..9************866 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

YRKIYEQGGK PNLLDMGSLL IKPVQRVMKY PLLLGELWQA TPEDHPDYRP LQEALTATKI 60
INVNINEFRR RKDIVMKYRR VEDESTLRGK LNKFNIHSIR KKGDRFAGYL KILTGVEPQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAAGGAGA AGGAGAAGGA GAAGGAGAAG GAGAAGGGGA TCAAGAGGAG GAACAGACCT 60
GTGTTCCTGC GCTACCTGGA GAGGAGAAAG ACAGACACTA TCGTGGCTGA AGACACAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS00741--DH_1
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003698	Anas platyrhynchos	50.28	1.00e-130	460.00
IUUC-Gmo-038829	Gadus morhua	73.24	0.00e+00	743.00
IUUC-Mga-060170	Meleagris gallopavo	53.31	2.00e-143	502.00
IUUC-Tni-120822	Tetraodon nigroviridis	85.55	0.00e+00	836.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence