iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003837

Ensembl Protein ID

ENSAPLP00000010339.1

UniProt Accession

U3ISW6; U3ISW6_ANAPL

Genbank Protein ID

ENSAPLP00000010339

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01095630

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000010593.1	ENSAPLT00000011051.1	ENSAPLP00000010339.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-23	81.5	113	145
UBD/Beta-Prp	6.20e-41	140.2	182	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H+ +v+c++f+++l+vsGs+D t kvW+l+ g+
   Q: 113  HEQEVNCVDFQGGLIVSGSRDRTAKVWSLSAGR 145
           99********669***************99887 PP

UBD/Beta-Prp

   S: 159  rtvrlWdlktgkllrtl.tgghtdsvysls.fdsngkelvsgsldgtvklwdlq..tgecvrtlng.htdnvksvrfspnderlvsgs. 241
           + +r+Wd ++g+ll+ l t + ++    l+ f ++   l+s+++d+++++wd++  t +cvr++++ h++  +++r +  ++ ++sgs 
   Q: 182  SPLRIWDFESGQLLTCLgT-DFHRGAGVLDvFYETPSLLLSCGYDTYIRYWDIRtsTRKCVREWEEpHDSALYCIRSD-GNHMIASGSs 268
           568**************54.45555555554888889*****************9999*******9899999999988.99999**997 PP
   S: 242  sDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniw 292
             g++r+Wd+r+  +l+++ l+  ++++v +l+f+  +l+++ + s ++++
   Q: 269  YYGVVRLWDKRQTRCLQSFHLSSPTSSPVYCLRFSTTHLYAALA-SALHVL 318
           89*********************************999987755.455555 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

AGIPVKERVK VSRNWRHGRC RRETVLKWKR NLMPWMELDG EYLYLSQAEN IQAYQLCPDG 60
TGLQRHPQAI FSGHQEDVCR FVLVNSHIVS GGGDGNIVLH KIHGSYSVKF SAHEQEVNCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGGCATCC CAGTGAAGGA GAGGGTGAAG GTCTCTCGCA ACTGGAGGCA TGGACGCTGC 60
CGGAGGGAGA CGGTCCTGAA ATGGAAACGA AAGCAAGTGG CTCCTTCCTC TTCTCCTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	71.91	3.00e-143	500.00
IUUC-Aca-004776	Anolis carolinensis	84.06	6.00e-148	516.00
IUUC-Ame-010651	Astyanax mexicanus	65.31	9.00e-121	426.00
IUUC-Bta-013495	Bos taurus	71.30	8.00e-135	473.00
IUUC-Cja-018901	Callithrix jacchus	71.74	2.00e-134	471.00
IUUC-Cfa-021251	Canis familiaris	71.60	3.00e-142	498.00
IUUC-Cpo-021750	Cavia porcellus	72.67	1.00e-142	498.00
IUUC-Csa-024026	Chlorocebus sabaeus	71.74	8.00e-142	496.00
IUUC-Cho-024496	Choloepus hoffmanni	53.09	7.00e-95	340.00
IUUC-Cin-025142	Ciona intestinalis	32.28	2.00e-21	95.90
IUUC-Csv-025883	Ciona savignyi	38.69	2.00e-66	245.00
IUUC-Dre-027447	Danio rerio	66.67	1.00e-124	439.00
IUUC-Dno-029572	Dasypus novemcinctus	63.77	6.00e-121	427.00
IUUC-Dor-030982	Dipodomys ordii	72.60	1.00e-129	455.00
IUUC-Dme-031804	Drosophila melanogaster	22.09	2.00e-14	73.20
IUUC-Ete-032917	Echinops telfairi	72.53	2.00e-144	504.00
IUUC-Eca-033969	Equus caballus	71.74	7.00e-135	473.00
IUUC-Eeu-034850	Erinaceus europaeus	66.67	2.00e-125	442.00
IUUC-Fca-036182	Felis catus	71.91	4.00e-143	500.00
IUUC-Fal-037391	Ficedula albicollis	95.96	0.00e+00	629.00
IUUC-Gmo-038632	Gadus morhua	62.19	6.00e-116	410.00
IUUC-Gga-040783	Gallus gallus	97.51	0.00e+00	650.00
IUUC-Gac-042314	Gasterosteus aculeatus	58.88	1.00e-96	345.00
IUUC-Ggo-044739	Gorilla gorilla	72.05	1.00e-141	495.00
IUUC-Hsa-046705	Homo sapiens	72.05	1.00e-134	472.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	72.66	6.00e-128	449.00
IUUC-Loc-052397	Lepisosteus oculatus	76.01	3.00e-141	494.00
IUUC-Laf-054544	Loxodonta africana	72.39	3.00e-143	500.00
IUUC-Meu-056363	Macropus eugenii	61.06	2.00e-101	361.00
IUUC-Mga-059275	Meleagris gallopavo	98.13	0.00e+00	654.00
IUUC-Mmr-060906	Microcebus murinus	71.43	8.00e-141	493.00
IUUC-Mdo-062400	Monodelphis domestica	81.93	2.00e-160	558.00
IUUC-Mmu-063556	Mus musculus	73.15	9.00e-144	502.00
IUUC-Mpu-066500	Mustela putorius furo	71.60	1.00e-142	498.00
IUUC-Mlu-068074	Myotis lucifugus	71.91	4.00e-143	499.00
IUUC-Nle-069601	Nomascus leucogenys	72.05	1.00e-141	495.00
IUUC-Opr-070904	Ochotona princeps	64.41	1.00e-90	325.00
IUUC-Ont-072679	Oreochromis niloticus	60.82	6.00e-116	410.00
IUUC-Oan-073434	Ornithorhynchus anatinus	77.06	5.00e-70	256.00
IUUC-Ocu-074649	Oryctolagus cuniculus	72.36	1.00e-142	498.00
IUUC-Ola-087336	Oryzias latipes	54.86	4.00e-93	334.00
IUUC-Oga-088590	Otolemur garnettii	70.59	1.00e-132	466.00
IUUC-Oar-090178	Ovis aries	71.60	2.00e-134	471.00
IUUC-Pan-092881	Papio anubis	71.74	8.00e-142	496.00
IUUC-Pfo-096176	Poecilia formosa	59.38	1.00e-101	362.00
IUUC-Pab-098285	Pongo abelii	72.05	1.00e-141	496.00
IUUC-Pca-100888	Procavia capensis	69.14	2.00e-128	451.00
IUUC-Pva-102184	Pteropus vampyrus	60.49	1.00e-110	392.00
IUUC-Rno-105668	Rattus norvegicus	71.43	6.00e-141	493.00
IUUC-Sha-106629	Sarcophilus harrisii	82.24	1.00e-161	561.00
IUUC-Ssc-116183	Sus scrofa	72.53	5.00e-144	504.00
IUUC-Tgu-116630	Taeniopygia guttata	95.96	0.00e+00	643.00
IUUC-Tru-118761	Takifugu rubripes	57.50	6.00e-106	377.00
IUUC-Tni-120651	Tetraodon nigroviridis	54.46	3.00e-63	234.00
IUUC-Ttr-128582	Tursiops truncatus	71.91	2.00e-133	468.00
IUUC-Vpa-130431	Vicugna pacos	58.87	5.00e-74	270.00
IUUC-Xtr-132655	Xenopus tropicalis	75.24	7.00e-145	506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence