iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012589

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

UBA2 protein

Genbank Nucleotide ID

DAAA02046904

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000002573.4	ENSBTAT00000003333.4	ENSBTAP00000003333.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.90e-138	461.7	10	421

Active Site

Position(s)	Description	Evidence
173	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 11   eaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           e  e++   +vl+vGagg+GcEllKnLvl+G+++i ++D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p+ n++a+++si++
   Q: 10   ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMN 98
           56799999********************************************************************************* PP
   S: 100  leeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtie 188
           ++++++Ff++f +V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+
   Q: 99   PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIV 187
           ***************************************************************************************** PP
   S: 189  wa.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv. 274
           wa +lfn+l++ee++++ev++  d++++e+++++ ++e+++++++++ +++++++k++ak+t ++ +k ++k f++di++  ++++++ 
   Q: 188  WAkYLFNQLFGEEDADQEVSP--DRADPEASWEPMEAEARARASNEDGDIKRVSTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWr 274
           *********************..799*************************************************************** PP
   S: 275  .................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaan 341
                            +  s ++++++p+ ++kd++v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aan
   Q: 275  krkppvpldwaevqsqgEETSASDQQNEPQLGLKDQQVLDVKSYaclfsKSIETLRVHLAEKGDGA---ELIWDKDDPSAMDFVTSAAN 360
           ******************************************************************...68****************** PP
   S: 342  lraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           lr++ +++++  ++++ik++agniipaiattnav++Gl+++E +K++sgk ++++++fl+++
   Q: 361  LRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQ 421
           **********.***********************************************9965 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MALSRGLPRE LAEAVAGGRV LVVGAGGIGC ELLKNLVLTG FSHIDLIDLD TIDVSNLNRQ 60
FLFQKKHVGR SKAQVAKESV LQFYPKANIV AYHDSIMNPD YNVEFFRQFI LVMNALDNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTTCTCCC GCCTCCGCCT CCGCCGCGGC TCGTGGTCGT CCCGCCATGG CACTGTCGAG 60
GGGGCTACCC CGGGAACTGG CTGAGGCCGT GGCCGGGGGC CGGGTCCTGG TGGTGGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

KEGG

bta:507005

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	40.44	2.00e-107	383.00
IUUC-Aml-001662	Ailuropoda melanoleuca	97.66	0.00e+00	1255.00
IUUC-Atr-002636	Amborella trichopoda	39.87	4.00e-112	399.00
IUUC-Apl-003369	Anas platyrhynchos	89.23	0.00e+00	1028.00
IUUC-Aca-004490	Anolis carolinensis	83.47	0.00e+00	922.00
IUUC-Aly-006359	Arabidopsis lyrata	41.76	1.00e-104	374.00
IUUC-Ath-007667	Arabidopsis thaliana	41.94	3.00e-108	385.00
IUUC-Ago-007844	Ashbya gossypii	36.74	9.00e-83	301.00
IUUC-Acl-008270	Aspergillus clavatus	41.81	4.00e-105	375.00
IUUC-Afl-008674	Aspergillus flavus	43.11	1.00e-111	397.00
IUUC-Afu-008883	Aspergillus fumigatus	41.45	1.00e-105	377.00
IUUC-Ani-009500	Aspergillus nidulans	45.07	2.00e-115	409.00
IUUC-Ang-009535	Aspergillus niger	44.23	1.00e-110	394.00
IUUC-Aor-010223	Aspergillus oryzae	44.06	7.00e-114	404.00
IUUC-Ate-010282	Aspergillus terreus	44.17	4.00e-90	325.00
IUUC-Ame-011736	Astyanax mexicanus	77.60	0.00e+00	987.00
IUUC-Bgr-012166	Blumeria graminis	42.34	2.00e-99	356.00
IUUC-Bci-013802	Botrytis cinerea	42.72	6.00e-101	361.00
IUUC-Bdi-014697	Brachypodium distachyon	41.76	1.00e-111	397.00
IUUC-Bol-016315	Brassica oleracea	39.66	2.00e-110	393.00
IUUC-Bra-017009	Brassica rapa	40.13	2.00e-111	396.00
IUUC-Cel-018708	Caenorhabditis elegans	46.67	1.00e-131	462.00
IUUC-Cja-019120	Callithrix jacchus	97.50	0.00e+00	1209.00
IUUC-Cfa-021061	Canis familiaris	98.28	0.00e+00	1266.00
IUUC-Cpo-021842	Cavia porcellus	96.72	0.00e+00	1202.00
IUUC-Csa-024104	Chlorocebus sabaeus	97.82	0.00e+00	1176.00
IUUC-Cho-024332	Choloepus hoffmanni	85.02	0.00e+00	868.00
IUUC-Cin-025363	Ciona intestinalis	56.54	0.00e+00	677.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	42.91	2.00e-99	357.00
IUUC-Cne-026888	Cryptococcus neoformans	53.41	8.00e-73	268.00
IUUC-Cme-027315	Cyanidioschyzon merolae	34.64	4.00e-60	226.00
IUUC-Dre-028420	Danio rerio	74.21	0.00e+00	912.00
IUUC-Dno-030041	Dasypus novemcinctus	96.88	0.00e+00	1206.00
IUUC-Dor-031039	Dipodomys ordii	81.56	0.00e+00	645.00
IUUC-Dse-031504	Dothistroma septosporum	42.76	2.00e-93	336.00
IUUC-Dme-031771	Drosophila melanogaster	50.08	2.00e-148	519.00
IUUC-Ete-033037	Echinops telfairi	91.56	0.00e+00	1090.00
IUUC-Eca-033774	Equus caballus	98.15	0.00e+00	1211.00
IUUC-Eeu-035074	Erinaceus europaeus	96.92	0.00e+00	972.00
IUUC-Fca-036508	Felis catus	98.15	0.00e+00	1212.00
IUUC-Fal-036813	Ficedula albicollis	87.22	0.00e+00	1019.00
IUUC-Fox-038056	Fusarium oxysporum	43.97	3.00e-106	379.00
IUUC-Fso-038223	Fusarium solani	43.83	3.00e-104	372.00
IUUC-Gmo-038526	Gadus morhua	74.88	0.00e+00	897.00
IUUC-Ggr-039767	Gaeumannomyces graminis	43.55	8.00e-100	358.00
IUUC-Gga-040981	Gallus gallus	88.12	0.00e+00	1053.00
IUUC-Gac-041437	Gasterosteus aculeatus	76.18	0.00e+00	920.00
IUUC-Gma-044072	Glycine max	37.63	5.00e-113	401.00
IUUC-Ggo-045358	Gorilla gorilla	94.43	0.00e+00	1119.00
IUUC-Hsa-046068	Homo sapiens	97.97	0.00e+00	1180.00
IUUC-Hvu-047646	Hordeum vulgare	38.15	3.00e-107	382.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	96.72	0.00e+00	1202.00
IUUC-Lch-049565	Latimeria chalumnae	81.65	0.00e+00	1039.00
IUUC-Lpe-050884	Leersia perrieri	40.64	3.00e-108	385.00
IUUC-Loc-052493	Lepisosteus oculatus	81.43	0.00e+00	1022.00
IUUC-Lma-053117	Leptosphaeria maculans	44.30	3.00e-101	362.00
IUUC-Laf-054518	Loxodonta africana	94.07	0.00e+00	1181.00
IUUC-Mcc-055334	Macaca mulatta	97.50	0.00e+00	1177.00
IUUC-Mor-057137	Magnaporthe oryzae	43.88	5.00e-94	338.00
IUUC-Mpo-057449	Magnaporthe poae	40.84	6.00e-102	365.00
IUUC-Mtr-058045	Medicago truncatula	40.06	5.00e-117	414.00
IUUC-Mla-058864	Melampsora laricipopulina	45.51	1.00e-95	343.00
IUUC-Mga-059422	Meleagris gallopavo	83.20	0.00e+00	932.00
IUUC-Mvi-060536	Microbotryum violaceum	42.80	1.00e-86	314.00
IUUC-Mmr-061161	Microcebus murinus	95.71	0.00e+00	1204.00
IUUC-Mdo-061802	Monodelphis domestica	92.20	0.00e+00	1138.00
IUUC-Mmu-064357	Mus musculus	93.59	0.00e+00	1200.00
IUUC-Mac-065475	Musa acuminata	39.10	2.00e-109	389.00
IUUC-Mpu-066895	Mustela putorius furo	98.44	0.00e+00	1267.00
IUUC-Mlu-067862	Myotis lucifugus	96.88	0.00e+00	1246.00
IUUC-Nfi-068385	Neosartorya fischeri	43.24	5.00e-109	388.00
IUUC-Ncr-068885	Neurospora crassa	41.83	6.00e-108	384.00
IUUC-Nle-069524	Nomascus leucogenys	97.19	0.00e+00	1162.00
IUUC-Opr-071038	Ochotona princeps	97.03	0.00e+00	1249.00
IUUC-Ont-071719	Oreochromis niloticus	75.99	0.00e+00	979.00
IUUC-Oan-072877	Ornithorhynchus anatinus	90.07	0.00e+00	993.00
IUUC-Ocu-074080	Oryctolagus cuniculus	97.19	0.00e+00	1204.00
IUUC-Oba-075936	Oryza barthii	39.74	8.00e-108	384.00
IUUC-Obr-076841	Oryza brachyantha	40.29	1.00e-109	390.00
IUUC-Ogl-077686	Oryza glaberrima	39.78	2.00e-109	389.00
IUUC-Ogu-078597	Oryza glumaepatula	38.68	7.00e-105	374.00
IUUC-Oin-079791	Oryza indica	39.74	8.00e-108	384.00
IUUC-Olo-081009	Oryza longistaminata	39.74	8.00e-108	384.00
IUUC-Ome-081327	Oryza meridionalis	36.78	6.00e-102	365.00
IUUC-Oni-082334	Oryza nivara	38.89	3.00e-105	376.00
IUUC-Opu-083447	Oryza punctata	38.13	1.00e-109	390.00
IUUC-Oru-084977	Oryza rufipogon	39.74	8.00e-108	384.00
IUUC-Osa-086160	Oryza sativa	43.49	3.00e-95	342.00
IUUC-Ola-087415	Oryzias latipes	75.59	0.00e+00	937.00
IUUC-Olu-087850	Ostreococcus lucimarinus	41.42	6.00e-101	361.00
IUUC-Oga-088434	Otolemur garnettii	96.88	0.00e+00	1205.00
IUUC-Oar-089872	Ovis aries	99.66	0.00e+00	1227.00
IUUC-Ptr-091212	Pan troglodytes	97.97	0.00e+00	1180.00
IUUC-Pan-092708	Papio anubis	98.46	9.00e-133	466.00
IUUC-Psi-093703	Pelodiscus sinensis	90.24	0.00e+00	1048.00
IUUC-Pno-094953	Phaeosphaeria nodorum	46.53	6.00e-105	374.00
IUUC-Ppa-095963	Physcomitrella patens	44.22	2.00e-107	383.00
IUUC-Pfo-097515	Poecilia formosa	75.55	0.00e+00	931.00
IUUC-Pab-097951	Pongo abelii	97.43	0.00e+00	1022.00
IUUC-Pop-099703	Populus trichocarpa	36.70	1.00e-96	347.00
IUUC-Pca-100426	Procavia capensis	95.31	0.00e+00	1217.00
IUUC-Ppe-101152	Prunus persica	39.22	5.00e-112	398.00
IUUC-Pva-102792	Pteropus vampyrus	93.42	0.00e+00	1165.00
IUUC-Pgr-103592	Puccinia graminis	43.95	1.00e-99	357.00
IUUC-Ptt-103805	Puccinia triticina	41.70	2.00e-85	310.00
IUUC-Pte-104215	Pyrenophora teres	44.31	2.00e-111	396.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	45.59	6.00e-110	391.00
IUUC-Rno-106117	Rattus norvegicus	93.91	0.00e+00	1204.00
IUUC-Sce-106177	Saccharomyces cerevisiae	37.72	5.00e-75	275.00
IUUC-Sha-107006	Sarcophilus harrisii	92.36	0.00e+00	1142.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	43.74	7.00e-94	338.00
IUUC-Spo-108020	Schizosaccharomyces pombe	44.17	5.00e-97	348.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	43.07	3.00e-103	369.00
IUUC-Smo-109264	Selaginella moellendorffii	43.57	4.00e-107	382.00
IUUC-Sit-110581	Setaria italica	40.48	1.00e-108	387.00
IUUC-Sly-111870	Solanum lycopersicum	39.74	3.00e-111	395.00
IUUC-Stu-112283	Solanum tuberosum	39.84	3.00e-109	389.00
IUUC-Sar-113432	Sorex araneus	72.39	0.00e+00	802.00
IUUC-Sbi-114075	Sorghum bicolor	38.74	1.00e-108	387.00
IUUC-Sre-114926	Sporisorium reilianum	42.81	2.00e-104	373.00
IUUC-Ssc-116281	Sus scrofa	99.08	2.00e-118	417.00
IUUC-Tgu-117247	Taeniopygia guttata	85.38	0.00e+00	1016.00
IUUC-Tru-118075	Takifugu rubripes	71.36	0.00e+00	894.00
IUUC-Tsy-119398	Tarsius syrichta	81.09	0.00e+00	929.00
IUUC-Tni-120771	Tetraodon nigroviridis	66.10	0.00e+00	809.00
IUUC-Tca-121651	Theobroma cacao	39.27	4.00e-110	392.00
IUUC-Tre-122224	Trichoderma reesei	43.23	3.00e-96	345.00
IUUC-Tvi-122634	Trichoderma virens	42.72	6.00e-96	345.00
IUUC-Tae-125665	Triticum aestivum	40.56	2.00e-105	375.00
IUUC-Tur-126417	Triticum urartu	39.60	4.00e-106	378.00
IUUC-Tme-127016	Tuber melanosporum	44.44	6.00e-96	344.00
IUUC-Tbe-127678	Tupaia belangeri	82.51	4.00e-180	624.00
IUUC-Ttr-128598	Tursiops truncatus	93.91	0.00e+00	1193.00
IUUC-Uma-129612	Ustilago maydis	41.04	3.00e-97	349.00
IUUC-Vda-129811	Verticillium dahliae	40.85	1.00e-101	363.00
IUUC-Vpa-130732	Vicugna pacos	83.91	0.00e+00	1035.00
IUUC-Vvi-130832	Vitis vinifera	41.88	5.00e-106	378.00
IUUC-Xtr-132823	Xenopus tropicalis	75.96	0.00e+00	919.00
IUUC-Xma-133552	Xiphophorus maculatus	75.39	0.00e+00	931.00
IUUC-Yli-134666	Yarrowia lipolytica	37.23	6.00e-75	275.00
IUUC-Zma-135547	Zea mays	38.81	9.00e-107	380.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence