iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089872

Ensembl Protein ID

ENSOARP00000004853.1

UniProt Accession

W5P353; W5P353_SHEEP

Genbank Protein ID

ENSOARP00000004853

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01028635

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000004533.1	ENSOART00000004935.1	ENSOARP00000004853.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	4.50e-118	395.2	1	375

Active Site

Position(s)	Description	Evidence
127	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 48   vDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkfdvVvlaldnrearrkvnrlclnarvp 136
           +D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p+ n+ a+++si++++++++Ff++f +V++aldnr+ar++vnr+cl+a+vp
   Q: 1    IDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIIAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVP 89
           7**************************************************************************************** PP
   S: 137  liesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.vlfnklleeeageeevlekldseekeegkdkvks 224
           liesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+wa +lfn+l++ee++++ev++  d++++e+++++ ++
   Q: 90   LIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAkYLFNQLFGEEDADQEVSP--DRADPEASWEPMEA 176
           *************************************************************************..799*********** PP
   S: 225  elksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv..................sfcsnaealqvpekvekdee 294
           e+++++++++ +++++++k++ak+t ++ +k ++k f++di++  ++++++                  +  s ++++++p+ ++kd++
   Q: 177  EARARASNEDGDIKRVSTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWrkrkppvpldwaevqsqgEETSASDQQNEPQLGLKDQQ 265
           ***************************************************************************************** PP
   S: 295  vvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgG 378
           v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aanlr++ +++++  ++++ik++agniipaiattnav++G
   Q: 266  VLDVKSYaclfsKSIETLRVHLAEKGDGA---ELIWDKDDPSAMDFVTSAANLRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAG 350
           *****************************...68****************************.************************** PP
   S: 379  laaqEviKvvsgkfeplknfflfda 403
           l+++E +K++sgk ++++++fl+++
   Q: 351  LIVLEGLKILSGKIDQCRTIFLNKQ 375
           *********************9965 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

IDLDTIDVSN LNRQFLFQKK HVGRSKAQVA KESVLQFYPK ANIIAYHDSI MNPDYNVEFF 60
RQFILVMNAL DNRAARNHVN RMCLAADVPL IESGTAGYLG QVTTIKKGVT ECYECHPKPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGATCTGG ATACTATTGA TGTCAGCAAC CTCAACAGGC AGTTTTTGTT TCAAAAGAAA 60
CATGTTGGAA GATCAAAGGC CCAGGTAATT GTATTTCTCA TATGGTTTCT ATTTATCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	38.80	1.00e-95	343.00
IUUC-Aml-001662	Ailuropoda melanoleuca	98.49	0.00e+00	1220.00
IUUC-Atr-002636	Amborella trichopoda	38.72	3.00e-97	349.00
IUUC-Apl-003369	Anas platyrhynchos	89.24	0.00e+00	1024.00
IUUC-Aca-004490	Anolis carolinensis	83.39	0.00e+00	897.00
IUUC-Aly-006359	Arabidopsis lyrata	40.35	8.00e-91	328.00
IUUC-Ath-007667	Arabidopsis thaliana	40.55	2.00e-94	340.00
IUUC-Ago-007844	Ashbya gossypii	34.80	1.00e-70	260.00
IUUC-Acl-008270	Aspergillus clavatus	40.68	2.00e-91	330.00
IUUC-Afl-008674	Aspergillus flavus	41.63	3.00e-97	349.00
IUUC-Afu-008883	Aspergillus fumigatus	40.04	3.00e-91	329.00
IUUC-Ani-009500	Aspergillus nidulans	43.57	5.00e-101	361.00
IUUC-Ang-009535	Aspergillus niger	42.77	7.00e-96	344.00
IUUC-Aor-010223	Aspergillus oryzae	42.44	2.00e-99	356.00
IUUC-Ate-010282	Aspergillus terreus	42.82	3.00e-76	279.00
IUUC-Ame-011736	Astyanax mexicanus	78.45	0.00e+00	932.00
IUUC-Bgr-012166	Blumeria graminis	41.27	6.00e-85	308.00
IUUC-Bta-012589	Bos taurus	99.66	0.00e+00	1226.00
IUUC-Bci-013802	Botrytis cinerea	41.56	2.00e-86	313.00
IUUC-Bdi-014697	Brachypodium distachyon	39.81	8.00e-99	354.00
IUUC-Bol-016315	Brassica oleracea	40.68	3.00e-96	345.00
IUUC-Bra-017009	Brassica rapa	38.61	5.00e-97	348.00
IUUC-Cel-018708	Caenorhabditis elegans	46.02	2.00e-117	416.00
IUUC-Cja-019120	Callithrix jacchus	97.31	0.00e+00	1153.00
IUUC-Cfa-021061	Canis familiaris	98.15	0.00e+00	1212.00
IUUC-Cpo-021842	Cavia porcellus	96.30	0.00e+00	1146.00
IUUC-Csa-024104	Chlorocebus sabaeus	97.65	0.00e+00	1131.00
IUUC-Cho-024332	Choloepus hoffmanni	87.50	0.00e+00	834.00
IUUC-Cin-025363	Ciona intestinalis	60.64	0.00e+00	626.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	40.79	3.00e-85	309.00
IUUC-Cne-026888	Cryptococcus neoformans	51.65	2.00e-58	220.00
IUUC-Cme-027315	Cyanidioschyzon merolae	32.94	1.00e-49	191.00
IUUC-Dre-028420	Danio rerio	75.17	0.00e+00	859.00
IUUC-Dno-030041	Dasypus novemcinctus	97.14	0.00e+00	1162.00
IUUC-Dor-031039	Dipodomys ordii	80.66	0.00e+00	645.00
IUUC-Dse-031504	Dothistroma septosporum	44.99	2.00e-84	306.00
IUUC-Dme-031771	Drosophila melanogaster	48.65	3.00e-135	475.00
IUUC-Ete-033037	Echinops telfairi	90.76	0.00e+00	1035.00
IUUC-Eca-033774	Equus caballus	98.15	0.00e+00	1208.00
IUUC-Eeu-035074	Erinaceus europaeus	96.72	0.00e+00	968.00
IUUC-Fca-036508	Felis catus	98.15	0.00e+00	1208.00
IUUC-Fal-036813	Ficedula albicollis	87.24	0.00e+00	1016.00
IUUC-Fox-038056	Fusarium oxysporum	42.25	8.00e-91	328.00
IUUC-Fso-038223	Fusarium solani	42.12	6.00e-89	321.00
IUUC-Gmo-038526	Gadus morhua	75.55	0.00e+00	843.00
IUUC-Ggr-039767	Gaeumannomyces graminis	41.81	2.00e-85	310.00
IUUC-Gga-040981	Gallus gallus	89.41	0.00e+00	986.00
IUUC-Gac-041437	Gasterosteus aculeatus	77.19	0.00e+00	866.00
IUUC-Gma-044072	Glycine max	36.28	6.00e-101	361.00
IUUC-Ggo-045358	Gorilla gorilla	94.00	0.00e+00	1075.00
IUUC-Hsa-046068	Homo sapiens	97.48	0.00e+00	1124.00
IUUC-Hvu-047646	Hordeum vulgare	37.10	1.00e-95	343.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	96.47	0.00e+00	1157.00
IUUC-Lch-049565	Latimeria chalumnae	82.44	0.00e+00	972.00
IUUC-Lpe-050884	Leersia perrieri	39.17	8.00e-97	347.00
IUUC-Loc-052493	Lepisosteus oculatus	82.05	0.00e+00	954.00
IUUC-Lma-053117	Leptosphaeria maculans	42.27	4.00e-88	318.00
IUUC-Laf-054518	Loxodonta africana	93.95	0.00e+00	1137.00
IUUC-Mcc-055334	Macaca mulatta	96.97	0.00e+00	1120.00
IUUC-Mor-057137	Magnaporthe oryzae	42.57	7.00e-80	291.00
IUUC-Mpo-057449	Magnaporthe poae	39.15	1.00e-87	317.00
IUUC-Mtr-058045	Medicago truncatula	39.04	6.00e-105	374.00
IUUC-Mla-058864	Melampsora laricipopulina	45.32	3.00e-85	308.00
IUUC-Mga-059422	Meleagris gallopavo	84.81	0.00e+00	921.00
IUUC-Mvi-060536	Microbotryum violaceum	40.97	1.00e-73	271.00
IUUC-Mmr-061161	Microcebus murinus	95.72	0.00e+00	1155.00
IUUC-Mdo-061802	Monodelphis domestica	92.11	0.00e+00	1087.00
IUUC-Mmu-064357	Mus musculus	93.11	0.00e+00	1105.00
IUUC-Mac-065475	Musa acuminata	37.65	1.00e-97	350.00
IUUC-Mpu-066895	Mustela putorius furo	98.32	0.00e+00	1212.00
IUUC-Mlu-067862	Myotis lucifugus	97.31	0.00e+00	1200.00
IUUC-Nfi-068385	Neosartorya fischeri	42.12	5.00e-95	341.00
IUUC-Ncr-068885	Neurospora crassa	40.11	4.00e-91	328.00
IUUC-Nle-069524	Nomascus leucogenys	96.64	0.00e+00	1107.00
IUUC-Opr-071038	Ochotona princeps	96.97	0.00e+00	1154.00
IUUC-Ont-071719	Oreochromis niloticus	77.25	0.00e+00	926.00
IUUC-Oan-072877	Ornithorhynchus anatinus	89.75	0.00e+00	988.00
IUUC-Ocu-074080	Oryctolagus cuniculus	96.97	0.00e+00	1151.00
IUUC-Oba-075936	Oryza barthii	38.27	3.00e-96	346.00
IUUC-Obr-076841	Oryza brachyantha	38.85	4.00e-98	352.00
IUUC-Ogl-077686	Oryza glaberrima	38.46	2.00e-96	347.00
IUUC-Ogu-078597	Oryza glumaepatula	37.20	3.00e-93	335.00
IUUC-Oin-079791	Oryza indica	38.27	3.00e-96	346.00
IUUC-Olo-081009	Oryza longistaminata	38.27	2.00e-96	346.00
IUUC-Ome-081327	Oryza meridionalis	38.46	7.00e-97	348.00
IUUC-Oni-082334	Oryza nivara	37.41	9.00e-94	337.00
IUUC-Opu-083447	Oryza punctata	38.46	2.00e-97	349.00
IUUC-Oru-084977	Oryza rufipogon	38.27	3.00e-96	345.00
IUUC-Osa-086160	Oryza sativa	41.73	8.00e-84	303.00
IUUC-Ola-087415	Oryzias latipes	76.66	0.00e+00	885.00
IUUC-Olu-087850	Ostreococcus lucimarinus	39.88	4.00e-89	322.00
IUUC-Oga-088434	Otolemur garnettii	96.81	0.00e+00	1154.00
IUUC-Ptr-091212	Pan troglodytes	97.48	0.00e+00	1124.00
IUUC-Pan-092708	Papio anubis	97.65	2.00e-117	415.00
IUUC-Psi-093703	Pelodiscus sinensis	90.25	0.00e+00	1044.00
IUUC-Pno-094953	Phaeosphaeria nodorum	44.47	5.00e-92	331.00
IUUC-Ppa-095963	Physcomitrella patens	42.02	1.00e-92	333.00
IUUC-Pfo-097515	Poecilia formosa	76.27	0.00e+00	874.00
IUUC-Pab-097951	Pongo abelii	97.25	0.00e+00	1018.00
IUUC-Pop-099703	Populus trichocarpa	35.37	2.00e-83	303.00
IUUC-Pca-100426	Procavia capensis	94.79	0.00e+00	1162.00
IUUC-Ppe-101152	Prunus persica	37.92	3.00e-98	352.00
IUUC-Pva-102792	Pteropus vampyrus	93.45	0.00e+00	1136.00
IUUC-Pgr-103592	Puccinia graminis	42.89	6.00e-88	318.00
IUUC-Ptt-103805	Puccinia triticina	39.67	8.00e-71	261.00
IUUC-Pte-104215	Pyrenophora teres	37.80	1.00e-98	353.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	37.29	3.00e-96	345.00
IUUC-Rno-105986	Rattus norvegicus	93.62	0.00e+00	1110.00
IUUC-Sce-106177	Saccharomyces cerevisiae	32.79	2.00e-65	243.00
IUUC-Sha-107006	Sarcophilus harrisii	92.28	0.00e+00	1093.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	41.85	1.00e-80	294.00
IUUC-Spo-108020	Schizosaccharomyces pombe	43.95	1.00e-84	306.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	41.94	8.00e-89	321.00
IUUC-Smo-109264	Selaginella moellendorffii	39.65	1.00e-93	337.00
IUUC-Sit-110581	Setaria italica	39.23	1.00e-96	347.00
IUUC-Sly-111870	Solanum lycopersicum	38.64	2.00e-98	352.00
IUUC-Stu-112283	Solanum tuberosum	38.74	2.00e-96	346.00
IUUC-Sar-113432	Sorex araneus	71.64	0.00e+00	772.00
IUUC-Sbi-114075	Sorghum bicolor	38.22	7.00e-96	344.00
IUUC-Sre-114926	Sporisorium reilianum	40.77	1.00e-89	323.00
IUUC-Ssc-116281	Sus scrofa	99.42	2.00e-103	368.00
IUUC-Tgu-117247	Taeniopygia guttata	85.40	0.00e+00	1011.00
IUUC-Tru-118075	Takifugu rubripes	72.28	0.00e+00	842.00
IUUC-Tsy-119398	Tarsius syrichta	79.66	0.00e+00	872.00
IUUC-Tni-120771	Tetraodon nigroviridis	66.78	0.00e+00	751.00
IUUC-Tca-121651	Theobroma cacao	38.45	8.00e-95	341.00
IUUC-Tre-122224	Trichoderma reesei	41.45	2.00e-81	296.00
IUUC-Tvi-122634	Trichoderma virens	41.30	3.00e-81	296.00
IUUC-Tae-125665	Triticum aestivum	38.90	2.00e-93	336.00
IUUC-Tur-126417	Triticum urartu	38.24	3.00e-93	335.00
IUUC-Tme-127016	Tuber melanosporum	42.44	8.00e-83	301.00
IUUC-Tbe-127678	Tupaia belangeri	82.29	2.00e-178	619.00
IUUC-Ttr-128598	Tursiops truncatus	93.28	0.00e+00	1137.00
IUUC-Uma-129612	Ustilago maydis	39.25	5.00e-82	298.00
IUUC-Vda-129811	Verticillium dahliae	38.47	2.00e-89	323.00
IUUC-Vpa-130732	Vicugna pacos	86.42	0.00e+00	986.00
IUUC-Vvi-130832	Vitis vinifera	38.62	2.00e-95	343.00
IUUC-Xtr-132823	Xenopus tropicalis	75.83	0.00e+00	913.00
IUUC-Xma-133552	Xiphophorus maculatus	76.10	0.00e+00	873.00
IUUC-Yli-134666	Yarrowia lipolytica	35.68	3.00e-60	226.00
IUUC-Zma-135547	Zea mays	38.54	1.00e-94	340.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence