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Tag Content
UUCD2 ID IUUC-Bta-013270
UUCD1 version UUC-BoT-00614
Ensembl Protein ID ENSBTAP00000042668.3
UniProt Accession F1MYE6; F1MYE6_BOVIN
Genbank Protein ID ENSBTAP00000042668
Protein Name Uncharacterized protein
Genbank Nucleotide ID DAAA02013251
Gene Name MDM2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000010422.5 ENSBTAT00000045265.3 ENSBTAP00000042668.3
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 93.90 0.00e+00 792.00 IUUC-Hsa-046376
E3 activity/RING/RING 79.07 0.00e+00 645.00 IUUC-Mmu-063207
E3 activity/RING/RING 82.69 0.00e+00 676.00 IUUC-Rno-105641
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Bos taurus
Protein Sequence
(Fasta)
MCNTNMSVST DGAVSTSQIP ASEQETLVRP KPLLLKLLKS VGAQKDTFTM KEVIFYLGQY 60
IMTKRLYDEK QQHIVYCSND LLGDLFGVPS FSVKEHRKIY TMIYRNLVVV SQQAEPSDSG 120
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Protein Fasta Sequence



>IUUC-Bta-013270|E3,RING|Bos taurus
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Nucleotide Sequence
(Fasta)
GCATCCGGCG CACCTCGGCC AGCTCGGCAG GTTTAGGGGC CTATGCGGCC CGGTGTGACT 60
GAAAGGAAAA TGGAGCAAGA AGCCTAGTCT GAGGGGTAGC CCTCACCCCT CTGACCGAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Bta-013270|E3,RING|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR028340--Mdm2
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005730--C:nucleolus
GO:0043234--C:protein complex
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0003283--P:atrial septum development
GO:0003181--P:atrioventricular valve morphogenesis
GO:0001568--P:blood vessel development
GO:0001974--P:blood vessel remodeling
GO:0060411--P:cardiac septum morphogenesis
GO:0071456--P:cellular response to hypoxia
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0003203--P:endocardial cushion morphogenesis
GO:0045184--P:establishment of protein localization
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0018205--P:peptidyl-lysine modification
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0006461--P:protein complex assembly
GO:0031648--P:protein destabilization
GO:0034504--P:protein localization to nucleus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0002027--P:regulation of heart rate
GO:0046677--P:response to antibiotic
GO:0007089--P:traversing start control point of mitotic cell cycle
GO:0003281--P:ventricular septum development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002039 Ailuropoda melanoleuca 93.50 0.00e+00 832.00
IUUC-Apl-003193 Anas platyrhynchos 64.36 2.00e-156 545.00
IUUC-Aca-004305 Anolis carolinensis 58.55 2.00e-122 432.00
IUUC-Ame-010675 Astyanax mexicanus 44.25 3.00e-85 309.00
IUUC-Cja-019744 Callithrix jacchus 91.30 0.00e+00 795.00
IUUC-Cfa-020807 Canis familiaris 92.03 0.00e+00 773.00
IUUC-Cpo-022182 Cavia porcellus 88.59 0.00e+00 744.00
IUUC-Cre-022828 Chlamydomonas reinhardtii 35.42 7.00e-06 41.60
IUUC-Csa-023541 Chlorocebus sabaeus 93.50 0.00e+00 806.00
IUUC-Cho-024831 Choloepus hoffmanni 75.09 1.00e-86 312.00
IUUC-Cin-025448 Ciona intestinalis 29.22 9.00e-23 100.00
IUUC-Csv-026151 Ciona savignyi 30.56 1.00e-10 60.50
IUUC-Dre-028419 Danio rerio 42.96 2.00e-50 192.00
IUUC-Dno-028950 Dasypus novemcinctus 91.26 0.00e+00 799.00
IUUC-Dor-031048 Dipodomys ordii 71.60 1.00e-170 592.00
IUUC-Ete-032264 Echinops telfairi 68.22 8.00e-171 593.00
IUUC-Eca-033301 Equus caballus 81.91 0.00e+00 719.00
IUUC-Eeu-035005 Erinaceus europaeus 80.08 0.00e+00 657.00
IUUC-Fca-035454 Felis catus 93.90 0.00e+00 827.00
IUUC-Fal-036720 Ficedula albicollis 61.24 5.00e-73 267.00
IUUC-Gmo-039296 Gadus morhua 41.04 9.00e-46 177.00
IUUC-Gga-040251 Gallus gallus 65.59 4.00e-153 534.00
IUUC-Ggo-044948 Gorilla gorilla 86.18 0.00e+00 737.00
IUUC-Hsa-046376 Homo sapiens 93.90 0.00e+00 811.00
IUUC-Itr-048328 Ictidomys tridecemlineatus 91.68 0.00e+00 766.00
IUUC-Lch-050037 Latimeria chalumnae 56.91 4.00e-117 414.00
IUUC-Loc-051837 Lepisosteus oculatus 50.30 2.00e-113 402.00
IUUC-Laf-053483 Loxodonta africana 84.18 0.00e+00 728.00
IUUC-Mcc-055294 Macaca mulatta 93.70 0.00e+00 810.00
IUUC-Mga-060007 Meleagris gallopavo 65.12 2.00e-150 525.00
IUUC-Mmr-060673 Microcebus murinus 93.09 0.00e+00 830.00
IUUC-Mdo-063057 Monodelphis domestica 75.05 0.00e+00 676.00
IUUC-Mmu-063207 Mus musculus 79.48 0.00e+00 638.00
IUUC-Mpu-065836 Mustela putorius furo 92.68 0.00e+00 833.00
IUUC-Mlu-068193 Myotis lucifugus 88.26 0.00e+00 789.00
IUUC-Nle-069927 Nomascus leucogenys 93.90 0.00e+00 812.00
IUUC-Opr-070590 Ochotona princeps 84.52 0.00e+00 709.00
IUUC-Ont-071984 Oreochromis niloticus 40.20 1.00e-72 267.00
IUUC-Oan-072744 Ornithorhynchus anatinus 72.01 6.00e-167 580.00
IUUC-Ocu-074071 Oryctolagus cuniculus 91.68 0.00e+00 788.00
IUUC-Ola-087329 Oryzias latipes 39.94 4.00e-50 192.00
IUUC-Oga-088135 Otolemur garnettii 83.27 0.00e+00 742.00
IUUC-Oar-090078 Ovis aries 98.37 0.00e+00 887.00
IUUC-Ptr-091399 Pan troglodytes 94.31 0.00e+00 815.00
IUUC-Pan-092720 Papio anubis 93.70 0.00e+00 810.00
IUUC-Psi-093591 Pelodiscus sinensis 66.16 1.00e-131 462.00
IUUC-Pma-094500 Petromyzon marinus 33.18 3.00e-24 104.00
IUUC-Pfo-096316 Poecilia formosa 38.28 8.00e-73 267.00
IUUC-Pab-097696 Pongo abelii 93.50 0.00e+00 802.00
IUUC-Pca-100974 Procavia capensis 82.15 0.00e+00 749.00
IUUC-Pva-102488 Pteropus vampyrus 88.01 0.00e+00 721.00
IUUC-Rno-105641 Rattus norvegicus 83.10 0.00e+00 684.00
IUUC-Sha-107314 Sarcophilus harrisii 73.33 0.00e+00 689.00
IUUC-Sar-112938 Sorex araneus 86.35 0.00e+00 769.00
IUUC-Ssc-115495 Sus scrofa 94.31 0.00e+00 807.00
IUUC-Tgu-116623 Taeniopygia guttata 64.25 8.00e-153 533.00
IUUC-Tru-117820 Takifugu rubripes 38.34 3.00e-69 255.00
IUUC-Tsy-119162 Tarsius syrichta 66.58 2.00e-90 325.00
IUUC-Tbe-127816 Tupaia belangeri 89.43 2.00e-121 429.00
IUUC-Ttr-129194 Tursiops truncatus 84.09 0.00e+00 676.00
IUUC-Vpa-130326 Vicugna pacos 88.82 0.00e+00 751.00
IUUC-Xtr-132216 Xenopus tropicalis 55.69 1.00e-122 432.00
Created Date 25-Jun-2017

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