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Tag Content
iUUCD ID IUUC-Sha-106845
Ensembl Protein ID ENSSHAP00000012136.1
UniProt Accession G3W9N1; G3W9N1_SARHA
Genbank Protein ID ENSSHAP00000012136
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEFK01128615
Gene Name ARHGEF7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000010398.1 ENSSHAT00000012233.1 ENSSHAP00000012135.1
ENSSHAG00000010398.1 ENSSHAT00000012234.1 ENSSHAP00000012136.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 6.50e-15 55.0 87 141
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
    +v++ ++++ +n+deL++ kGd+++v +++gW++g + +gk G fP+n+v++++
   Q: 87 VVRAKFNFQQTNEDELSFAKGDIIHVT--RVEEGGWWEG--THNGKTGWFPSNYVREIK 141
    68999*********************7..999*******..8**************997 PP
   

Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
MGIKTFDAND LYQGQNFNKV LSSLVTLNKV TADIGLGSDS VCARPSSHRI KSFDSLGSQS 60
LLNRTSKLFQ GQYRSLDMTD NSNHQLVVRA KFNFQQTNED ELSFAKGDII HVTRVEEGGW 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Sha-106845|UBD,SH3|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTTATGTGTA CAACACAAAA ATCTTTATGT TGTTAATAGT GAAATATTTG TTATAACTGC 60
TTTCTTTAGT CATGTATGTT GTGCAAGGAC CTGGGGAAGA AAATTCTACA GCCTTAGATG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Sha-106845|UBD,SH3|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000322--C:storage vacuole
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0048041--P:focal adhesion assembly
GO:0007030--P:Golgi organization
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0030032--P:lamellipodium assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0010763--P:positive regulation of fibroblast migration
GO:0060124--P:positive regulation of growth hormone secretion
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0032092--P:positive regulation of protein binding
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:1904424--P:regulation of GTP binding
GO:0035023--P:regulation of Rho protein signal transduction

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001259 Ailuropoda melanoleuca 92.41 0.00e+00 1120.00
IUUC-Apl-003960 Anas platyrhynchos 61.64 0.00e+00 831.00
IUUC-Aca-004591 Anolis carolinensis 92.70 0.00e+00 1081.00
IUUC-Ame-010759 Astyanax mexicanus 74.65 0.00e+00 914.00
IUUC-Bta-013328 Bos taurus 91.10 0.00e+00 1100.00
IUUC-Bci-013864 Botrytis cinerea 41.54 3.00e-11 64.30
IUUC-Cja-018742 Callithrix jacchus 92.41 0.00e+00 1116.00
IUUC-Cfa-020756 Canis familiaris 93.50 0.00e+00 1305.00
IUUC-Cpo-021284 Cavia porcellus 90.98 0.00e+00 1079.00
IUUC-Csa-023162 Chlorocebus sabaeus 92.56 0.00e+00 1123.00
IUUC-Cho-024736 Choloepus hoffmanni 74.82 1.00e-175 609.00
IUUC-Cin-025535 Ciona intestinalis 40.31 1.00e-93 336.00
IUUC-Cgl-026676 Colletotrichum gloeosporioides 42.86 2.00e-11 65.50
IUUC-Cne-026866 Cryptococcus neoformans 49.21 2.00e-12 68.90
IUUC-Dre-028646 Danio rerio 64.58 0.00e+00 925.00
IUUC-Dno-029461 Dasypus novemcinctus 94.78 0.00e+00 1148.00
IUUC-Dor-030623 Dipodomys ordii 81.69 0.00e+00 951.00
IUUC-Dme-032219 Drosophila melanogaster 44.33 5.00e-101 362.00
IUUC-Ete-032236 Echinops telfairi 81.06 0.00e+00 808.00
IUUC-Eca-034137 Equus caballus 94.28 0.00e+00 1135.00
IUUC-Eeu-035269 Erinaceus europaeus 57.92 6.00e-81 295.00
IUUC-Fca-035742 Felis catus 93.77 0.00e+00 1276.00
IUUC-Fal-037205 Ficedula albicollis 95.14 0.00e+00 1003.00
IUUC-Fso-038433 Fusarium solani 41.67 4.00e-12 67.40
IUUC-Gmo-039475 Gadus morhua 74.93 0.00e+00 1003.00
IUUC-Gga-040539 Gallus gallus 95.67 0.00e+00 1175.00
IUUC-Gac-042615 Gasterosteus aculeatus 71.47 0.00e+00 927.00
IUUC-Ggo-044470 Gorilla gorilla 92.41 0.00e+00 1120.00
IUUC-Hsa-046398 Homo sapiens 92.41 0.00e+00 1116.00
IUUC-Kpa-049278 Komagataella pastoris 27.20 7.00e-17 82.80
IUUC-Lch-049517 Latimeria chalumnae 62.18 0.00e+00 848.00
IUUC-Loc-052146 Lepisosteus oculatus 85.42 0.00e+00 1043.00
IUUC-Laf-053891 Loxodonta africana 93.65 0.00e+00 1167.00
IUUC-Mcc-055483 Macaca mulatta 92.83 0.00e+00 1115.00
IUUC-Meu-056285 Macropus eugenii 53.18 6.00e-117 414.00
IUUC-Mtr-058576 Medicago truncatula 56.82 2.00e-10 59.70
IUUC-Mla-059044 Melampsora laricipopulina 26.16 2.00e-19 91.30
IUUC-Mga-059410 Meleagris gallopavo 94.15 0.00e+00 1140.00
IUUC-Mmr-060758 Microcebus murinus 92.72 0.00e+00 1079.00
IUUC-Mdo-061900 Monodelphis domestica 98.76 0.00e+00 1367.00
IUUC-Mmu-063849 Mus musculus 90.66 0.00e+00 1071.00
IUUC-Mpu-065876 Mustela putorius furo 93.06 0.00e+00 1291.00
IUUC-Mlu-067970 Myotis lucifugus 93.48 0.00e+00 1126.00
IUUC-Nle-069685 Nomascus leucogenys 90.71 0.00e+00 1190.00
IUUC-Opr-071132 Ochotona princeps 58.28 6.00e-178 617.00
IUUC-Ont-071815 Oreochromis niloticus 67.39 0.00e+00 976.00
IUUC-Oan-073057 Ornithorhynchus anatinus 95.86 0.00e+00 1019.00
IUUC-Ocu-074852 Oryctolagus cuniculus 58.86 0.00e+00 784.00
IUUC-Ola-086663 Oryzias latipes 65.86 0.00e+00 919.00
IUUC-Oga-088103 Otolemur garnettii 91.30 0.00e+00 1067.00
IUUC-Oar-089339 Ovis aries 59.00 0.00e+00 811.00
IUUC-Ptr-091162 Pan troglodytes 92.25 0.00e+00 1114.00
IUUC-Pan-092093 Papio anubis 79.88 0.00e+00 977.00
IUUC-Psi-093116 Pelodiscus sinensis 62.05 0.00e+00 859.00
IUUC-Pma-094261 Petromyzon marinus 64.98 1.00e-124 439.00
IUUC-Pfo-096736 Poecilia formosa 74.10 0.00e+00 1021.00
IUUC-Pab-097641 Pongo abelii 93.64 0.00e+00 1302.00
IUUC-Pca-100997 Procavia capensis 54.52 0.00e+00 642.00
IUUC-Pva-102819 Pteropus vampyrus 89.68 0.00e+00 1061.00
IUUC-Rno-106099 Rattus norvegicus 90.66 0.00e+00 1075.00
IUUC-Sar-113420 Sorex araneus 58.02 0.00e+00 754.00
IUUC-Ssc-116036 Sus scrofa 91.84 0.00e+00 1267.00
IUUC-Tgu-117498 Taeniopygia guttata 94.30 0.00e+00 1141.00
IUUC-Tru-118278 Takifugu rubripes 73.10 0.00e+00 863.00
IUUC-Tsy-118990 Tarsius syrichta 90.84 0.00e+00 947.00
IUUC-Tni-120852 Tetraodon nigroviridis 73.19 0.00e+00 1004.00
IUUC-Tbe-127994 Tupaia belangeri 46.79 7.00e-174 603.00
IUUC-Ttr-128922 Tursiops truncatus 88.06 0.00e+00 1029.00
IUUC-Vpa-130144 Vicugna pacos 53.24 0.00e+00 672.00
IUUC-Xtr-132012 Xenopus tropicalis 84.04 0.00e+00 925.00
Created Date 25-Jun-2017

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