iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-44	146.8	623	661
UBD/Beta-Prp	6.60e-88	295.1	471	792

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH ++v+c +f ++ +++++Gs D t+++WD+  g++++
   Q: 623  GHLADVNCTRFhPNsNYVATGSADRTVRLWDVLNGNCVR 661
           89**********777*****************9999986 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl...............................lrslsgheaevtavkfspdgkilvtg 70
           +t+v++++d+sl+a g++d+t++vw+vt++kl                               l+ l+gh+++v+  +fspd+++l+++
   Q: 471  LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLrsvkqasdlslidkesddvlerimdektaseLKILYGHSGPVYGASFSPDRNYLLSS 559
           799************************************************************************************** PP
   S: 71   seDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDr 159
           seD+t+++w+l+t++c++ +kgh++ v++++fsp+g+++vsG+hdr++r+w ++++q l+ +++gh + vnc+++hp++n++++Gs+Dr
   Q: 560  SEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLR-IFAGHLADVNCTRFHPNSNYVATGSADR 647
           ************************************************************.**************************** PP
   S: 160  tvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiri 248
           tvrlWd+ +g+++r +tg h+++++sl+f++ng++l++g++dg+v lwd+ +g +v +l+ghtd+v+s+rfs+++e+l+sgs+D+++r+
   Q: 648  TVRLWDVLNGNCVRIFTG-HKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRL 735
           *****************9.********************************************************************** PP
   S: 249  W.......dlrsgdllktlqlhn..............ssvisvavlsfgdnvlvlgs 284
           W       dl+++d+++++ + n              +++++v +l+f++++lvl++
   Q: 736  WdaikafeDLETDDFTTATGHINlpensqelllgtymTKSTPVVHLHFTRRNLVLAA 792
           ****************************************************99986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAALAEEQTE VAVKLESEGP PTLLPPQAGD GAGEGSGGTP NNGPNGGGGN VAAAAGGDGG 60
TPKPVVAVSA AAPAGAAPVP AAPAEAGAPH DRQTLLAVLQ FLRQSNLREA EEALRREARL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGAGGTGG CTCAGCCGCA AGATGGCGGC GCTGGCGGAG GAGCAGACGG AGGTGGCGGT 60
CAAGCTAGAG TCTGAGGGAC CGCCAACGCT GCTACCTCCG CAGGCTGGCG ACGGCGCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0000790--C:nuclear chromatin
GO:0005669--C:transcription factor TFIID complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0044212--F:transcription regulatory region DNA binding
GO:0006367--P:transcription initiation from RNA polymerase II promoter

KEGG

rno:294018

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000851	Aegilops tauschii	51.93	9.00e-69	254.00
IUUC-Aml-001607	Ailuropoda melanoleuca	96.50	0.00e+00	1281.00
IUUC-Atr-003136	Amborella trichopoda	46.48	3.00e-95	342.00
IUUC-Apl-004193	Anas platyrhynchos	92.67	0.00e+00	1133.00
IUUC-Aca-004522	Anolis carolinensis	85.31	0.00e+00	1205.00
IUUC-Aly-006476	Arabidopsis lyrata	38.24	6.00e-115	408.00
IUUC-Ath-006587	Arabidopsis thaliana	47.19	4.00e-88	319.00
IUUC-Ago-007736	Ashbya gossypii	42.82	2.00e-93	336.00
IUUC-Acl-008092	Aspergillus clavatus	36.34	2.00e-78	287.00
IUUC-Afl-008659	Aspergillus flavus	36.60	7.00e-80	291.00
IUUC-Afu-008902	Aspergillus fumigatus	37.96	4.00e-80	292.00
IUUC-Ani-009462	Aspergillus nidulans	38.39	3.00e-81	296.00
IUUC-Aor-010083	Aspergillus oryzae	36.60	8.00e-80	291.00
IUUC-Ate-010271	Aspergillus terreus	37.76	5.00e-80	292.00
IUUC-Ame-010721	Astyanax mexicanus	80.48	0.00e+00	1114.00
IUUC-Bgr-012257	Blumeria graminis	29.65	1.00e-74	274.00
IUUC-Bta-013539	Bos taurus	96.47	0.00e+00	1281.00
IUUC-Bci-013737	Botrytis cinerea	28.98	1.00e-79	291.00
IUUC-Bdi-015041	Brachypodium distachyon	48.94	7.00e-84	305.00
IUUC-Bol-016198	Brassica oleracea	37.52	2.00e-112	399.00
IUUC-Bra-017660	Brassica rapa	37.15	9.00e-112	397.00
IUUC-Cel-018451	Caenorhabditis elegans	33.73	4.00e-87	315.00
IUUC-Cja-018881	Callithrix jacchus	98.17	0.00e+00	1258.00
IUUC-Cfa-020056	Canis familiaris	97.32	0.00e+00	1295.00
IUUC-Cpo-021454	Cavia porcellus	88.31	0.00e+00	1251.00
IUUC-Cre-022736	Chlamydomonas reinhardtii	40.07	4.00e-52	199.00
IUUC-Csa-023045	Chlorocebus sabaeus	99.83	0.00e+00	1166.00
IUUC-Cho-024284	Choloepus hoffmanni	85.83	0.00e+00	969.00
IUUC-Cin-025457	Ciona intestinalis	60.29	3.00e-100	357.00
IUUC-Csv-025882	Ciona savignyi	51.88	4.00e-180	624.00
IUUC-Cgl-026392	Colletotrichum gloeosporioides	28.74	5.00e-77	282.00
IUUC-Cne-026876	Cryptococcus neoformans	39.39	3.00e-73	270.00
IUUC-Cme-027302	Cyanidioschyzon merolae	34.41	1.00e-101	363.00
IUUC-Dre-027980	Danio rerio	79.69	0.00e+00	1084.00
IUUC-Dno-028863	Dasypus novemcinctus	97.74	0.00e+00	1241.00
IUUC-Dor-030561	Dipodomys ordii	98.03	0.00e+00	1242.00
IUUC-Dse-031547	Dothistroma septosporum	30.71	1.00e-78	288.00
IUUC-Dme-031917	Drosophila melanogaster	41.01	9.00e-148	517.00
IUUC-Ete-032319	Echinops telfairi	80.10	0.00e+00	919.00
IUUC-Eca-033927	Equus caballus	91.69	0.00e+00	1252.00
IUUC-Eeu-034449	Erinaceus europaeus	99.19	0.00e+00	964.00
IUUC-Fca-036325	Felis catus	97.32	0.00e+00	1261.00
IUUC-Fal-036604	Ficedula albicollis	94.92	0.00e+00	1164.00
IUUC-Fox-038049	Fusarium oxysporum	33.05	2.00e-49	191.00
IUUC-Gmo-038832	Gadus morhua	74.82	0.00e+00	1018.00
IUUC-Ggr-039878	Gaeumannomyces graminis	29.03	1.00e-71	264.00
IUUC-Gga-041147	Gallus gallus	94.90	0.00e+00	1186.00
IUUC-Gac-041373	Gasterosteus aculeatus	79.07	0.00e+00	1069.00
IUUC-Gma-043230	Glycine max	38.40	7.00e-119	421.00
IUUC-Ggo-045526	Gorilla gorilla	96.91	0.00e+00	851.00
IUUC-Hsa-045971	Homo sapiens	97.74	0.00e+00	1257.00
IUUC-Hvu-047695	Hordeum vulgare	49.71	4.00e-87	315.00
IUUC-Itr-048400	Ictidomys tridecemlineatus	97.32	0.00e+00	1295.00
IUUC-Kpa-049402	Komagataella pastoris	43.80	5.00e-95	342.00
IUUC-Lch-049526	Latimeria chalumnae	88.11	0.00e+00	1064.00
IUUC-Lpe-050793	Leersia perrieri	36.72	1.00e-87	317.00
IUUC-Loc-052882	Lepisosteus oculatus	81.88	0.00e+00	1140.00
IUUC-Lma-053212	Leptosphaeria maculans	31.64	3.00e-80	293.00
IUUC-Laf-053859	Loxodonta africana	97.60	0.00e+00	1282.00
IUUC-Mcc-054957	Macaca mulatta	100.00	0.00e+00	999.00
IUUC-Meu-056766	Macropus eugenii	98.07	0.00e+00	673.00
IUUC-Mor-057024	Magnaporthe oryzae	29.01	9.00e-68	251.00
IUUC-Mpo-057520	Magnaporthe poae	29.52	9.00e-72	264.00
IUUC-Mtr-058754	Medicago truncatula	39.02	6.00e-122	431.00
IUUC-Mla-058881	Melampsora laricipopulina	38.21	3.00e-80	293.00
IUUC-Mga-059776	Meleagris gallopavo	94.93	0.00e+00	1189.00
IUUC-Mvi-060208	Microbotryum violaceum	41.75	2.00e-83	304.00
IUUC-Mmr-061783	Microcebus murinus	100.00	0.00e+00	999.00
IUUC-Mdo-062856	Monodelphis domestica	90.48	0.00e+00	1211.00
IUUC-Mmu-064218	Mus musculus	99.29	0.00e+00	1316.00
IUUC-Mac-064886	Musa acuminata	53.05	3.00e-72	266.00
IUUC-Mpu-065735	Mustela putorius furo	97.04	0.00e+00	1276.00
IUUC-Mlu-067544	Myotis lucifugus	99.19	0.00e+00	1211.00
IUUC-Nfi-068502	Neosartorya fischeri	37.96	2.00e-80	293.00
IUUC-Ncr-068891	Neurospora crassa	30.00	6.00e-76	278.00
IUUC-Nle-069389	Nomascus leucogenys	98.17	0.00e+00	1273.00
IUUC-Opr-071042	Ochotona princeps	87.94	0.00e+00	677.00
IUUC-Ont-071455	Oreochromis niloticus	80.76	0.00e+00	1096.00
IUUC-Oan-073181	Ornithorhynchus anatinus	95.28	0.00e+00	1177.00
IUUC-Ocu-073758	Oryctolagus cuniculus	94.50	0.00e+00	1293.00
IUUC-Oba-075739	Oryza barthii	44.89	1.00e-81	297.00
IUUC-Obr-076111	Oryza brachyantha	38.40	5.00e-113	401.00
IUUC-Ogl-077914	Oryza glaberrima	37.03	4.00e-100	358.00
IUUC-Ogu-078190	Oryza glumaepatula	35.12	1.00e-89	323.00
IUUC-Oin-079249	Oryza indica	37.58	1.00e-100	360.00
IUUC-Olo-080645	Oryza longistaminata	52.47	2.00e-69	256.00
IUUC-Ome-081831	Oryza meridionalis	42.20	8.00e-72	264.00
IUUC-Oni-082431	Oryza nivara	36.26	2.00e-98	353.00
IUUC-Opu-083325	Oryza punctata	35.44	2.00e-91	329.00
IUUC-Oru-085154	Oryza rufipogon	52.19	5.00e-81	295.00
IUUC-Osa-086189	Oryza sativa	38.16	5.00e-104	371.00
IUUC-Ola-086574	Oryzias latipes	82.01	0.00e+00	1122.00
IUUC-Olu-087616	Ostreococcus lucimarinus	33.23	1.00e-100	360.00
IUUC-Oga-088827	Otolemur garnettii	95.50	0.00e+00	1276.00
IUUC-Oar-089648	Ovis aries	96.61	0.00e+00	1281.00
IUUC-Ptr-091195	Pan troglodytes	97.74	0.00e+00	1291.00
IUUC-Pan-091978	Papio anubis	97.74	0.00e+00	1271.00
IUUC-Psi-093598	Pelodiscus sinensis	94.77	0.00e+00	1070.00
IUUC-Pno-094823	Phaeosphaeria nodorum	30.53	6.00e-84	305.00
IUUC-Ppa-095455	Physcomitrella patens	45.92	1.00e-95	343.00
IUUC-Pfo-097120	Poecilia formosa	80.93	0.00e+00	1081.00
IUUC-Pab-098771	Pongo abelii	98.03	0.00e+00	1271.00
IUUC-Pop-099542	Populus trichocarpa	37.60	1.00e-116	413.00
IUUC-Pca-100804	Procavia capensis	88.89	0.00e+00	934.00
IUUC-Ppe-101686	Prunus persica	38.63	6.00e-111	394.00
IUUC-Pva-102414	Pteropus vampyrus	92.81	0.00e+00	1199.00
IUUC-Pgr-103603	Puccinia graminis	37.24	1.00e-73	271.00
IUUC-Pte-104359	Pyrenophora teres	30.02	7.00e-83	301.00
IUUC-Pyt-104523	Pyrenophora triticirepentis	29.71	9.00e-84	304.00
IUUC-Sce-106186	Saccharomyces cerevisiae	42.75	3.00e-91	329.00
IUUC-Sha-106582	Sarcophilus harrisii	98.05	0.00e+00	1199.00
IUUC-Sja-107683	Schizosaccharomyces japonicus	38.09	1.00e-109	390.00
IUUC-Spo-108142	Schizosaccharomyces pombe	36.12	7.00e-107	381.00
IUUC-Ssl-108456	Sclerotinia sclerotiorum	28.29	7.00e-79	288.00
IUUC-Smo-109111	Selaginella moellendorffii	36.90	5.00e-107	381.00
IUUC-Sit-109804	Setaria italica	38.33	1.00e-106	380.00
IUUC-Sly-111693	Solanum lycopersicum	37.38	6.00e-110	391.00
IUUC-Sar-113412	Sorex araneus	93.82	0.00e+00	802.00
IUUC-Sbi-114849	Sorghum bicolor	37.50	7.00e-105	374.00
IUUC-Sre-114945	Sporisorium reilianum	35.37	1.00e-77	284.00
IUUC-Ssc-115582	Sus scrofa	77.74	0.00e+00	920.00
IUUC-Tgu-116899	Taeniopygia guttata	88.05	0.00e+00	1184.00
IUUC-Tru-118011	Takifugu rubripes	79.38	0.00e+00	1096.00
IUUC-Tni-120598	Tetraodon nigroviridis	79.89	0.00e+00	1087.00
IUUC-Tca-121247	Theobroma cacao	44.73	7.00e-95	341.00
IUUC-Tre-121949	Trichoderma reesei	36.41	7.00e-63	235.00
IUUC-Tvi-122626	Trichoderma virens	32.89	2.00e-64	240.00
IUUC-Tae-123335	Triticum aestivum	50.29	4.00e-89	322.00
IUUC-Tur-126005	Triticum urartu	45.17	1.00e-82	301.00
IUUC-Tme-126904	Tuber melanosporum	42.38	2.00e-91	330.00
IUUC-Tbe-127254	Tupaia belangeri	92.10	0.00e+00	1228.00
IUUC-Ttr-128544	Tursiops truncatus	97.46	0.00e+00	1254.00
IUUC-Uma-129379	Ustilago maydis	34.31	2.00e-77	284.00
IUUC-Vda-129761	Verticillium dahliae	33.67	1.00e-58	221.00
IUUC-Vpa-130485	Vicugna pacos	97.18	0.00e+00	1258.00
IUUC-Vvi-131171	Vitis vinifera	37.48	2.00e-116	413.00
IUUC-Xtr-132762	Xenopus tropicalis	73.04	0.00e+00	978.00
IUUC-Xma-133583	Xiphophorus maculatus	80.48	0.00e+00	1083.00
IUUC-Yli-134446	Yarrowia lipolytica	37.90	1.00e-117	417.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence