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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018674
UUCD1 version UUC-CaE-00362
Ensembl Protein ID M02A10.3a
UniProt Accession Q19019; Q19019_CAEEL
Genbank Protein ID CAA61507.1; CCD62721.1
Protein Name Sli-1 protein; Suppressor of LIneage defect
Genbank Nucleotide ID X89223; BX284606
Gene Name sli-1; CELE_M02A10.3; M02A10.3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00004829 M02A10.3a M02A10.3a
WBGene00004829 M02A10.3b M02A10.3b
WBGene00004829 M02A10.3c M02A10.3c
Annotation
mRNA Expression
GEO
DNA & RNA Element
microRNAmiRNAMapRAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 23271977
Classification
Family E-value Score Start End
E3 activity/RING/RING 9.90e-07 29.5 390 431
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC +  k+  ++ pCgH+ +a+Cl +w   ++s  +  +CP Cr
   Q: 390  CKICDDNEKN-IKIEPCGHLLCAKCLANW---QDSDGGGNTCPFCR 431
           99**776677.******************...77799********8 PP
   
Organism Caenorhabditis elegans
Protein Sequence
(Fasta)
MGSINTIFHR IHRFVNGTGN NARFVPSTNN STEALTLSPR AVPSTVSLFE IPSASEMPGF 60
CSEEDRRFLL KACKFMDQVV KSCHSPRLNL KNSPPFILDI LPDTYTHLML IFTQNNDILQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018674|E3,RING|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTATGATCAT TACATCCTAA TTAATTGCCA CTGGACTTCA CATCATATCA CCGTTTCACC 60
GGGAATGGGT TCAATAAACA CAATTTTTCA CCGGATACAT CGGTTTGTCA ATGGCACAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018674|E3,RING|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3
SMART

SM00184--RING
Gene Ontology

GO:0045121--C:membrane raft
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0040027--P:negative regulation of vulval development
GO:0006508--P:proteolysis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001412 Ailuropoda melanoleuca 56.92 8.00e-134 470.00
IUUC-Atr-003107 Amborella trichopoda 37.25 6.00e-07 46.20
IUUC-Apl-004148 Anas platyrhynchos 56.17 6.00e-134 470.00
IUUC-Aca-005204 Anolis carolinensis 56.92 3.00e-134 471.00
IUUC-Aly-006538 Arabidopsis lyrata 30.77 5.00e-06 43.10
IUUC-Ath-007365 Arabidopsis thaliana 37.29 4.00e-06 48.10
IUUC-Ame-011919 Astyanax mexicanus 56.20 7.00e-124 437.00
IUUC-Bta-013044 Bos taurus 56.92 8.00e-134 470.00
IUUC-Bol-015478 Brassica oleracea 38.98 3.00e-06 48.90
IUUC-Bra-017001 Brassica rapa 40.68 1.00e-06 49.70
IUUC-Cja-019207 Callithrix jacchus 54.90 1.00e-133 469.00
IUUC-Cfa-021054 Canis familiaris 56.92 3.00e-134 471.00
IUUC-Cpo-022514 Cavia porcellus 56.92 2.00e-134 471.00
IUUC-Csa-024110 Chlorocebus sabaeus 56.92 8.00e-134 470.00
IUUC-Cho-024282 Choloepus hoffmanni 45.62 2.00e-101 362.00
IUUC-Cin-025574 Ciona intestinalis 55.56 4.00e-128 449.00
IUUC-Csv-025938 Ciona savignyi 53.81 6.00e-126 442.00
IUUC-Dre-027480 Danio rerio 57.18 5.00e-134 470.00
IUUC-Dno-028923 Dasypus novemcinctus 56.67 4.00e-133 467.00
IUUC-Dor-031040 Dipodomys ordii 48.72 5.00e-104 370.00
IUUC-Dme-032213 Drosophila melanogaster 53.63 1.00e-137 483.00
IUUC-Ete-032406 Echinops telfairi 57.33 4.00e-129 454.00
IUUC-Eca-033849 Equus caballus 56.92 9.00e-134 469.00
IUUC-Eeu-035142 Erinaceus europaeus 47.59 2.00e-105 375.00
IUUC-Fca-036224 Felis catus 56.92 5.00e-134 470.00
IUUC-Fal-036860 Ficedula albicollis 56.67 1.00e-133 469.00
IUUC-Gmo-038698 Gadus morhua 54.90 4.00e-133 468.00
IUUC-Gga-040159 Gallus gallus 56.67 2.00e-133 469.00
IUUC-Gac-042166 Gasterosteus aculeatus 55.15 7.00e-134 470.00
IUUC-Gma-043487 Glycine max 33.90 5.00e-06 48.10
IUUC-Ggo-045618 Gorilla gorilla 54.90 2.00e-133 469.00
IUUC-Hsa-046306 Homo sapiens 56.92 8.00e-134 470.00
IUUC-Itr-048795 Ictidomys tridecemlineatus 58.33 3.00e-110 390.00
IUUC-Lch-050552 Latimeria chalumnae 48.46 2.00e-137 481.00
IUUC-Loc-052570 Lepisosteus oculatus 55.41 7.00e-134 470.00
IUUC-Lma-053133 Leptosphaeria maculans 29.58 2.00e-07 48.10
IUUC-Laf-054008 Loxodonta africana 55.50 2.00e-132 465.00
IUUC-Mcc-055536 Macaca mulatta 56.92 7.00e-134 470.00
IUUC-Meu-056045 Macropus eugenii 46.67 1.00e-99 356.00
IUUC-Mtr-058211 Medicago truncatula 36.21 3.00e-06 48.90
IUUC-Mga-059239 Meleagris gallopavo 54.90 2.00e-133 468.00
IUUC-Mmr-061088 Microcebus murinus 56.92 6.00e-134 470.00
IUUC-Mdo-062020 Monodelphis domestica 56.92 7.00e-134 470.00
IUUC-Mmu-063114 Mus musculus 56.92 6.00e-134 470.00
IUUC-Mpu-066632 Mustela putorius furo 56.92 5.00e-134 471.00
IUUC-Mlu-067145 Myotis lucifugus 56.92 9.00e-134 469.00
IUUC-Nle-069285 Nomascus leucogenys 54.90 2.00e-133 468.00
IUUC-Opr-071026 Ochotona princeps 55.61 2.00e-130 458.00
IUUC-Ont-071954 Oreochromis niloticus 53.85 2.00e-134 471.00
IUUC-Oan-073165 Ornithorhynchus anatinus 56.92 3.00e-134 471.00
IUUC-Ocu-074723 Oryctolagus cuniculus 56.92 6.00e-134 470.00
IUUC-Ola-087165 Oryzias latipes 55.15 2.00e-134 472.00
IUUC-Oga-088021 Otolemur garnettii 56.92 8.00e-134 470.00
IUUC-Oar-089809 Ovis aries 56.92 1.00e-133 469.00
IUUC-Ptr-090834 Pan troglodytes 56.92 7.00e-134 470.00
IUUC-Pan-092225 Papio anubis 56.92 5.00e-134 470.00
IUUC-Psi-093317 Pelodiscus sinensis 56.67 3.00e-134 471.00
IUUC-Pma-094249 Petromyzon marinus 49.38 2.00e-69 254.00
IUUC-Ppa-095308 Physcomitrella patens 23.62 8.00e-08 49.30
IUUC-Pfo-096990 Poecilia formosa 54.90 3.00e-133 468.00
IUUC-Pab-097595 Pongo abelii 56.92 8.00e-134 470.00
IUUC-Pop-099439 Populus trichocarpa 27.56 3.00e-07 52.00
IUUC-Pca-100844 Procavia capensis 44.62 2.00e-88 319.00
IUUC-Ppe-101533 Prunus persica 37.29 9.00e-07 50.40
IUUC-Pva-103216 Pteropus vampyrus 56.92 7.00e-134 470.00
IUUC-Rno-105381 Rattus norvegicus 56.92 4.00e-134 471.00
IUUC-Sha-107574 Sarcophilus harrisii 56.92 6.00e-134 470.00
IUUC-Smo-108709 Selaginella moellendorffii 39.29 3.00e-07 44.70
IUUC-Sly-111502 Solanum lycopersicum 35.59 1.00e-07 50.10
IUUC-Sar-112959 Sorex araneus 55.61 2.00e-130 458.00
IUUC-Ssc-115261 Sus scrofa 54.90 1.00e-133 469.00
IUUC-Tgu-116866 Taeniopygia guttata 56.67 2.00e-133 468.00
IUUC-Tru-118300 Takifugu rubripes 55.41 3.00e-134 471.00
IUUC-Tsy-119167 Tarsius syrichta 59.26 2.00e-104 372.00
IUUC-Tni-119861 Tetraodon nigroviridis 55.41 4.00e-134 471.00
IUUC-Tca-120945 Theobroma cacao 36.54 9.00e-07 50.40
IUUC-Tbe-128018 Tupaia belangeri 55.61 3.00e-130 457.00
IUUC-Ttr-128631 Tursiops truncatus 56.92 7.00e-134 470.00
IUUC-Vpa-130713 Vicugna pacos 56.92 1.00e-133 469.00
IUUC-Vvi-131667 Vitis vinifera 34.62 6.00e-06 47.80
IUUC-Xtr-131926 Xenopus tropicalis 53.92 2.00e-134 472.00
Created Date 25-Jun-2017

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