iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089646

Ensembl Protein ID

ENSOARP00000000153.1

UniProt Accession

W5NPR3; W5NPR3_SHEEP

Genbank Protein ID

ENSOARP00000000153

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01019203

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000000175.1	ENSOART00000000179.1	ENSOARP00000000153.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	90.39	4.00e-102	368.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MVTHSKFPAA GMSRPLDASL RLKTFSSKSE YQLVVNAVRK LQESGFYWST VTGGEANLLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120

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Nucleotide Sequence
(Fasta)

ATGGTCACCC ACAGCAAGTT CCCCGCCGCC GGGATGAGCC GCCCCCTGGA CGCCAGCCTG 60
CGCCTCAAGA CCTTCAGCTC CAAGAGCGAG TACCAGCTGG TGGTGAACGC AGTGCGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2

SMART

SM00252--SH2
SM00253--SOCS

Gene Ontology

GO:0005622--C:intracellular
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0060674--P:placenta blood vessel development
GO:0045597--P:positive regulation of cell differentiation
GO:0060708--P:spongiotrophoblast differentiation
GO:0060707--P:trophoblast giant cell differentiation

KEGG

oas:100294595

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	86.46	2.00e-101	361.00
IUUC-Apl-003607	Anas platyrhynchos	79.04	1.00e-92	332.00
IUUC-Aca-005063	Anolis carolinensis	77.92	5.00e-98	350.00
IUUC-Ath-006990	Arabidopsis thaliana	32.94	8.00e-03	36.20
IUUC-Ame-010859	Astyanax mexicanus	54.27	3.00e-66	244.00
IUUC-Bta-012817	Bos taurus	96.51	1.00e-110	392.00
IUUC-Cja-019605	Callithrix jacchus	89.52	5.00e-109	386.00
IUUC-Cfa-021231	Canis familiaris	89.08	3.00e-103	367.00
IUUC-Cpo-022003	Cavia porcellus	87.77	4.00e-103	366.00
IUUC-Csa-023511	Chlorocebus sabaeus	90.39	3.00e-107	380.00
IUUC-Dre-028536	Danio rerio	58.12	1.00e-71	261.00
IUUC-Dno-029003	Dasypus novemcinctus	85.59	9.00e-105	372.00
IUUC-Eca-034205	Equus caballus	87.15	3.00e-66	243.00
IUUC-Fca-036317	Felis catus	88.99	9.00e-103	365.00
IUUC-Gmo-038777	Gadus morhua	62.96	3.00e-35	140.00
IUUC-Gga-041258	Gallus gallus	79.04	1.00e-92	332.00
IUUC-Gac-041837	Gasterosteus aculeatus	52.79	4.00e-61	227.00
IUUC-Ggo-045620	Gorilla gorilla	90.39	3.00e-107	380.00
IUUC-Hsa-046909	Homo sapiens	90.39	3.00e-107	380.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	91.88	9.00e-109	385.00
IUUC-Lch-049510	Latimeria chalumnae	64.38	6.00e-80	289.00
IUUC-Loc-052863	Lepisosteus oculatus	61.11	7.00e-77	279.00
IUUC-Laf-054136	Loxodonta africana	89.96	6.00e-105	373.00
IUUC-Mcc-055383	Macaca mulatta	90.39	3.00e-107	380.00
IUUC-Meu-056153	Macropus eugenii	84.72	1.00e-105	375.00
IUUC-Mmr-061185	Microcebus murinus	88.21	1.00e-103	368.00
IUUC-Mdo-061819	Monodelphis domestica	85.15	7.00e-107	379.00
IUUC-Mmu-064231	Mus musculus	89.52	1.00e-109	389.00
IUUC-Mpu-066691	Mustela putorius furo	88.65	3.00e-103	367.00
IUUC-Mlu-067673	Myotis lucifugus	88.65	7.00e-110	389.00
IUUC-Ont-072406	Oreochromis niloticus	52.79	4.00e-65	240.00
IUUC-Oan-073249	Ornithorhynchus anatinus	72.93	1.00e-90	325.00
IUUC-Ocu-074935	Oryctolagus cuniculus	82.61	2.00e-29	119.00
IUUC-Ola-087373	Oryzias latipes	44.76	3.00e-44	171.00
IUUC-Oga-088041	Otolemur garnettii	87.77	4.00e-105	373.00
IUUC-Ptr-091502	Pan troglodytes	90.39	3.00e-107	380.00
IUUC-Pan-091934	Papio anubis	90.39	3.00e-107	380.00
IUUC-Pfo-096412	Poecilia formosa	39.91	1.00e-44	172.00
IUUC-Pab-098554	Pongo abelii	90.39	3.00e-107	380.00
IUUC-Rno-105874	Rattus norvegicus	88.65	1.00e-109	388.00
IUUC-Sha-107151	Sarcophilus harrisii	84.72	3.00e-106	377.00
IUUC-Ssc-115722	Sus scrofa	79.55	2.00e-61	227.00
IUUC-Tgu-117151	Taeniopygia guttata	78.60	5.00e-92	329.00
IUUC-Tru-118428	Takifugu rubripes	51.50	1.00e-63	235.00
IUUC-Tni-120590	Tetraodon nigroviridis	51.93	6.00e-63	233.00
IUUC-Ttr-129065	Tursiops truncatus	95.63	2.00e-108	384.00
IUUC-Xtr-132167	Xenopus tropicalis	64.19	7.00e-80	289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence