iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034319

Ensembl Protein ID

ENSECAP00000020917.1

UniProt Accession

F6USF3; F6USF3_HORSE

Protein Name

Uncharacterized protein

Gene Name

ZNF106

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000023311.1	ENSECAT00000025152.1	ENSECAP00000020917.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.70e-18	63.8	1583	1623
UBD/Beta-Prp	9.90e-47	159.7	1538	1723

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtl...lvsGsdDgtikvWDlrtgvll 36
           gHt++v+cl     s+     l +Gs D+ti++++++t  ++
   Q: 1583 GHTSKVNCLLVtqtSG-KnaaLYTGSSDHTIRCYNVKTRECV 1623
           8*******95587533.24579**************998886 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqc 128
             s++gh+a+v+a+++  +  +l t+s D+t++ ++l ++kc+ +++gh+++v +l + +   ++  l +Gs+d tir+++++t++c
   Q: 1538 EGSFEGHQAAVNAIQIFGN--LLYTCSADKTVRAYNLVSRKCIGVFEGHTSKVNCLLVTQtsgKNAALYTGSSDHTIRCYNVKTREC 1622
           5789*************99..9*********************************99999755558899****************** PP
   S: 129  leetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwdlqtge 213
           +e  l+ +d   +++++h+  ++l +G +++tv  +++k++k l+ ++    ++v +l+  ++g  k lv gs+d t+ + d ++g 
   Q: 1623 VE-QLQLED---RVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGarKLLVVGSYDCTISVRDARNGL 1705
           *9.777777...566677767**************************9977899999**99999999******************** PP
   S: 214  cvrtlnghtdnvksvrfs 231
            +rtl+gh+++++++++s
   Q: 1706 LLRTLEGHSKTILCMKAS 1723
           **************9876 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MVRERKCILC HIVYSSKKEM DEHMRSMLHH RELENLKGRD SSHECRVCGV TEVGLSAYAK 60
HISGQLHKDN VDAQEREDDG KGEEEEEDYF DKELVQLIKQ RKEQSRQDEP SNSSQEINSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTACGAG AACGAAAATG CATATTGTGC CACATTGTGT ACAGCTCAAA AAAGGTAATA 60
ATAGTAGAAG GAGAATCTGA GGCTTAATGA CTGATCATTT TTTCAGAGAC ATCATATGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR018391--PQQ_beta_propeller_repeat
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013087--Znf_C2H2_type

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00028--ZINC_FINGER_C2H2_1

Pfam

PF00400--WD40

SMART

SM00564--PQQ
SM00320--WD40
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0016020--C:membrane
GO:0046872--F:metal ion binding
GO:0003723--F:RNA binding
GO:0017124--F:SH3 domain binding
GO:0008286--P:insulin receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001928	Ailuropoda melanoleuca	90.06	0.00e+00	3216.00
IUUC-Apl-003674	Anas platyrhynchos	58.70	0.00e+00	1822.00
IUUC-Aca-005018	Anolis carolinensis	54.28	0.00e+00	1719.00
IUUC-Ame-011431	Astyanax mexicanus	68.30	0.00e+00	677.00
IUUC-Bta-013436	Bos taurus	89.09	0.00e+00	3209.00
IUUC-Cfa-020278	Canis familiaris	89.55	0.00e+00	2759.00
IUUC-Cpo-022278	Cavia porcellus	79.37	0.00e+00	2811.00
IUUC-Csa-023115	Chlorocebus sabaeus	86.31	0.00e+00	1914.00
IUUC-Cho-024829	Choloepus hoffmanni	81.19	0.00e+00	2162.00
IUUC-Dre-028112	Danio rerio	59.63	0.00e+00	667.00
IUUC-Dno-029127	Dasypus novemcinctus	85.51	0.00e+00	3039.00
IUUC-Dor-030367	Dipodomys ordii	80.21	0.00e+00	1190.00
IUUC-Ete-032500	Echinops telfairi	73.81	0.00e+00	1243.00
IUUC-Eeu-034754	Erinaceus europaeus	77.99	0.00e+00	2386.00
IUUC-Fca-036181	Felis catus	90.20	0.00e+00	3140.00
IUUC-Fal-036865	Ficedula albicollis	56.50	0.00e+00	1671.00
IUUC-Gmo-039227	Gadus morhua	63.79	3.00e-174	605.00
IUUC-Gga-041178	Gallus gallus	57.91	0.00e+00	1838.00
IUUC-Gac-042209	Gasterosteus aculeatus	64.34	1.00e-166	580.00
IUUC-Ggo-044636	Gorilla gorilla	88.08	0.00e+00	3212.00
IUUC-Hsa-045949	Homo sapiens	89.42	0.00e+00	3142.00
IUUC-Itr-048628	Ictidomys tridecemlineatus	87.71	0.00e+00	3066.00
IUUC-Lch-049753	Latimeria chalumnae	50.10	0.00e+00	1528.00
IUUC-Loc-052333	Lepisosteus oculatus	68.99	0.00e+00	723.00
IUUC-Laf-053530	Loxodonta africana	84.61	0.00e+00	3095.00
IUUC-Mcc-054664	Macaca mulatta	88.89	0.00e+00	3079.00
IUUC-Meu-056609	Macropus eugenii	66.85	0.00e+00	1223.00
IUUC-Mga-059632	Meleagris gallopavo	58.64	0.00e+00	1826.00
IUUC-Mmr-060742	Microcebus murinus	88.24	0.00e+00	3079.00
IUUC-Mdo-061831	Monodelphis domestica	82.27	0.00e+00	1323.00
IUUC-Mmu-064055	Mus musculus	77.46	0.00e+00	2611.00
IUUC-Mpu-066458	Mustela putorius furo	92.50	0.00e+00	1573.00
IUUC-Mlu-067767	Myotis lucifugus	86.78	0.00e+00	3089.00
IUUC-Nle-069728	Nomascus leucogenys	88.94	0.00e+00	3106.00
IUUC-Opr-070914	Ochotona princeps	79.25	0.00e+00	2713.00
IUUC-Ont-072353	Oreochromis niloticus	67.95	0.00e+00	642.00
IUUC-Ocu-073827	Oryctolagus cuniculus	86.43	0.00e+00	2939.00
IUUC-Ola-087573	Oryzias latipes	67.40	6.00e-161	560.00
IUUC-Oga-088664	Otolemur garnettii	88.74	0.00e+00	1834.00
IUUC-Oar-090256	Ovis aries	86.62	0.00e+00	2518.00
IUUC-Ptr-090884	Pan troglodytes	87.73	0.00e+00	2648.00
IUUC-Pan-091779	Papio anubis	86.31	0.00e+00	1912.00
IUUC-Psi-093267	Pelodiscus sinensis	91.73	6.00e-163	565.00
IUUC-Pma-094414	Petromyzon marinus	43.39	4.00e-58	219.00
IUUC-Pfo-097009	Poecilia formosa	63.77	3.00e-158	553.00
IUUC-Pca-100820	Procavia capensis	79.38	0.00e+00	2185.00
IUUC-Pva-103044	Pteropus vampyrus	83.52	0.00e+00	1250.00
IUUC-Rno-105960	Rattus norvegicus	71.44	0.00e+00	2382.00
IUUC-Sar-113018	Sorex araneus	76.76	0.00e+00	1334.00
IUUC-Ssc-115278	Sus scrofa	89.00	0.00e+00	3218.00
IUUC-Tgu-117231	Taeniopygia guttata	56.17	0.00e+00	1718.00
IUUC-Tru-118472	Takifugu rubripes	55.94	2.00e-165	577.00
IUUC-Tsy-118877	Tarsius syrichta	82.98	0.00e+00	2009.00
IUUC-Tni-119881	Tetraodon nigroviridis	57.31	1.00e-177	618.00
IUUC-Tbe-127499	Tupaia belangeri	80.09	0.00e+00	1604.00
IUUC-Ttr-128962	Tursiops truncatus	90.17	0.00e+00	3103.00
IUUC-Vpa-130089	Vicugna pacos	83.41	0.00e+00	1373.00
IUUC-Xtr-132940	Xenopus tropicalis	47.74	0.00e+00	1394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence