iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048040

Ensembl Protein ID

ENSSTOP00000012034.2

UniProt Accession

I3MKZ9; I3MKZ9_ICTTR

Genbank Protein ID

ENSSTOP00000012034

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01081271

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000013429.2	ENSSTOT00000013429.2	ENSSTOP00000012034.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-21	75.8	633	671

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 633  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 671
           8***********999*********************998 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MFPQSRHPTP HQAAGQPFKF TIPESLDRIK EEFQFLQAQY HSLKLECEKL ASEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTICA QVIPFLSQEH QQQVAQAVER AKQVTMAELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTAATTTT CCTCGGCGGG ATTAAAGTTG GAAATTGAGC GGAGAATTGA GTTGTCCGGG 60
AACCGAGCCG CGGCAGCCGC CAGAGCGATG TTCCCGCAGA GCCGGCACCC GGTGAGCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003594	Anas platyrhynchos	91.98	0.00e+00	1219.00
IUUC-Aca-005053	Anolis carolinensis	94.81	0.00e+00	1276.00
IUUC-Ame-011935	Astyanax mexicanus	78.81	0.00e+00	1105.00
IUUC-Cfa-020611	Canis familiaris	98.78	0.00e+00	1063.00
IUUC-Cin-025767	Ciona intestinalis	57.76	7.00e-170	590.00
IUUC-Dre-028326	Danio rerio	78.63	0.00e+00	1098.00
IUUC-Dno-029011	Dasypus novemcinctus	98.61	0.00e+00	1063.00
IUUC-Eeu-034666	Erinaceus europaeus	98.78	0.00e+00	1066.00
IUUC-Fal-036696	Ficedula albicollis	93.87	0.00e+00	1222.00
IUUC-Gmo-038805	Gadus morhua	80.86	0.00e+00	1182.00
IUUC-Gga-041113	Gallus gallus	94.43	0.00e+00	1330.00
IUUC-Lch-050437	Latimeria chalumnae	90.67	0.00e+00	1097.00
IUUC-Loc-052819	Lepisosteus oculatus	92.16	0.00e+00	1220.00
IUUC-Laf-053862	Loxodonta africana	98.08	0.00e+00	1067.00
IUUC-Mmr-061207	Microcebus murinus	98.43	0.00e+00	1057.00
IUUC-Mdo-062493	Monodelphis domestica	95.19	0.00e+00	1325.00
IUUC-Mmu-063795	Mus musculus	95.33	0.00e+00	1260.00
IUUC-Ont-072102	Oreochromis niloticus	80.48	0.00e+00	1187.00
IUUC-Ocu-074592	Oryctolagus cuniculus	92.53	0.00e+00	1293.00
IUUC-Oga-088629	Otolemur garnettii	98.43	0.00e+00	1063.00
IUUC-Psi-093594	Pelodiscus sinensis	96.04	0.00e+00	1264.00
IUUC-Pca-100675	Procavia capensis	98.08	0.00e+00	1051.00
IUUC-Pva-102355	Pteropus vampyrus	93.55	0.00e+00	974.00
IUUC-Rno-106027	Rattus norvegicus	93.94	0.00e+00	1294.00
IUUC-Sha-107419	Sarcophilus harrisii	91.09	0.00e+00	1251.00
IUUC-Sar-113585	Sorex araneus	85.54	0.00e+00	708.00
IUUC-Tgu-117387	Taeniopygia guttata	94.43	0.00e+00	1312.00
IUUC-Tsy-119342	Tarsius syrichta	94.25	0.00e+00	976.00
IUUC-Xtr-131792	Xenopus tropicalis	88.04	0.00e+00	1215.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence