iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062171

Ensembl Protein ID

ENSMODP00000003405.3

UniProt Accession

F7EJJ9; F7EJJ9_MONDO

Protein Name

Uncharacterized protein

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000002800.3	ENSMODT00000003476.3	ENSMODP00000003405.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	5.20e-51	172.3	15	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           ats+l+ ++dwe+il+icd+i++ +++ak+a+ +++k++n+knphval+aL++++s+v+nCg+++h+eva+k+++eel+ellk+++e++
   Q: 15   ATSQLLLETDWESILQICDMIRQGDTQAKYAVSSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKELLKRQVEVN 103
           799************************************************************************************** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v++K+++li++Wa++++nep++++++++++ +k eG++fp
   Q: 104  VRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 143
           ***************************************8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGRGSGTFER LLDKATSQLL LETDWESILQ ICDMIRQGDT QAKYAVSSIK KKVNDKNPHV 60
ALYALEVMES VVKNCGQTVH DEVANKQTME ELKELLKRQV EVNVRNKILY LIQAWAHAFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAGAG GTAGCGGCAC CTTCGAGCGT CTCCTAGGTA ACGTGCCCCC AGACGGACAG 60
CTTCCCCCAC CCCCCTCCTC TCCAGCGTGG CTCTGGGGCA GCCCGGGCCT GCCTCATACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	85.35	0.00e+00	1006.00
IUUC-Apl-003662	Anas platyrhynchos	84.85	0.00e+00	1014.00
IUUC-Aca-004940	Anolis carolinensis	85.60	0.00e+00	1192.00
IUUC-Ago-007931	Ashbya gossypii	30.58	8.00e-27	115.00
IUUC-Acl-008274	Aspergillus clavatus	30.32	6.00e-39	155.00
IUUC-Afl-008521	Aspergillus flavus	32.50	3.00e-40	160.00
IUUC-Afu-008774	Aspergillus fumigatus	32.59	7.00e-41	162.00
IUUC-Ani-009445	Aspergillus nidulans	32.22	8.00e-41	162.00
IUUC-Ang-009863	Aspergillus niger	32.85	4.00e-42	166.00
IUUC-Ate-010444	Aspergillus terreus	34.80	2.00e-42	166.00
IUUC-Ame-011111	Astyanax mexicanus	81.12	0.00e+00	971.00
IUUC-Bgr-012087	Blumeria graminis	33.21	3.00e-42	167.00
IUUC-Bta-012506	Bos taurus	90.00	0.00e+00	1161.00
IUUC-Bci-013782	Botrytis cinerea	31.38	8.00e-42	165.00
IUUC-Cel-018493	Caenorhabditis elegans	53.33	4.00e-68	252.00
IUUC-Cja-019998	Callithrix jacchus	85.26	0.00e+00	1060.00
IUUC-Cfa-020615	Canis familiaris	86.72	0.00e+00	1096.00
IUUC-Cpo-022019	Cavia porcellus	88.63	0.00e+00	1204.00
IUUC-Csa-023596	Chlorocebus sabaeus	87.16	0.00e+00	1053.00
IUUC-Cin-025488	Ciona intestinalis	47.76	3.00e-128	452.00
IUUC-Csv-025802	Ciona savignyi	49.45	1.00e-114	406.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	33.33	6.00e-40	159.00
IUUC-Cne-026847	Cryptococcus neoformans	32.23	6.00e-38	152.00
IUUC-Dre-028353	Danio rerio	78.37	0.00e+00	944.00
IUUC-Dno-029005	Dasypus novemcinctus	87.28	0.00e+00	1133.00
IUUC-Dor-030280	Dipodomys ordii	86.49	0.00e+00	1130.00
IUUC-Dse-031238	Dothistroma septosporum	38.71	2.00e-42	167.00
IUUC-Dme-031952	Drosophila melanogaster	47.21	8.00e-79	288.00
IUUC-Ete-032235	Echinops telfairi	96.36	3.00e-131	462.00
IUUC-Eca-033873	Equus caballus	89.86	0.00e+00	1145.00
IUUC-Eeu-034652	Erinaceus europaeus	96.09	5.00e-105	375.00
IUUC-Fca-036563	Felis catus	88.33	0.00e+00	1136.00
IUUC-Fal-036649	Ficedula albicollis	86.09	0.00e+00	1065.00
IUUC-Fox-037962	Fusarium oxysporum	33.46	1.00e-39	158.00
IUUC-Fso-038396	Fusarium solani	33.70	7.00e-40	159.00
IUUC-Gmo-039510	Gadus morhua	77.48	0.00e+00	978.00
IUUC-Ggr-039938	Gaeumannomyces graminis	31.90	2.00e-37	150.00
IUUC-Gga-040201	Gallus gallus	84.38	0.00e+00	1143.00
IUUC-Gac-041459	Gasterosteus aculeatus	76.60	0.00e+00	981.00
IUUC-Ggo-044573	Gorilla gorilla	88.70	0.00e+00	1153.00
IUUC-Hsa-046009	Homo sapiens	88.83	0.00e+00	1198.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	87.20	0.00e+00	1197.00
IUUC-Kpa-049327	Komagataella pastoris	29.71	2.00e-32	134.00
IUUC-Lch-049944	Latimeria chalumnae	82.74	7.00e-172	596.00
IUUC-Loc-051850	Lepisosteus oculatus	82.54	0.00e+00	1053.00
IUUC-Lma-053252	Leptosphaeria maculans	35.65	6.00e-41	162.00
IUUC-Laf-053346	Loxodonta africana	81.82	0.00e+00	1039.00
IUUC-Mcc-055789	Macaca mulatta	87.97	0.00e+00	1122.00
IUUC-Meu-056329	Macropus eugenii	85.02	0.00e+00	656.00
IUUC-Mor-057205	Magnaporthe oryzae	33.22	3.00e-38	153.00
IUUC-Mpo-057295	Magnaporthe poae	33.01	5.00e-39	156.00
IUUC-Mla-058849	Melampsora laricipopulina	31.74	7.00e-32	132.00
IUUC-Mga-059361	Meleagris gallopavo	84.03	0.00e+00	1073.00
IUUC-Mvi-060561	Microbotryum violaceum	32.66	9.00e-40	158.00
IUUC-Mmr-061122	Microcebus murinus	90.58	0.00e+00	995.00
IUUC-Mmu-063952	Mus musculus	88.17	0.00e+00	1239.00
IUUC-Mpu-065852	Mustela putorius furo	87.20	0.00e+00	1098.00
IUUC-Mlu-066996	Myotis lucifugus	79.77	2.00e-144	505.00
IUUC-Nfi-068539	Neosartorya fischeri	32.59	3.00e-41	163.00
IUUC-Ncr-068726	Neurospora crassa	39.91	2.00e-39	157.00
IUUC-Nle-070148	Nomascus leucogenys	84.34	0.00e+00	1044.00
IUUC-Opr-070833	Ochotona princeps	69.40	0.00e+00	755.00
IUUC-Ont-071261	Oreochromis niloticus	79.08	0.00e+00	983.00
IUUC-Oan-073684	Ornithorhynchus anatinus	72.69	5.00e-163	567.00
IUUC-Ola-087570	Oryzias latipes	77.04	0.00e+00	991.00
IUUC-Oga-089087	Otolemur garnettii	85.56	0.00e+00	1050.00
IUUC-Oar-089534	Ovis aries	90.14	0.00e+00	1164.00
IUUC-Ptr-091654	Pan troglodytes	83.18	0.00e+00	1043.00
IUUC-Pan-092652	Papio anubis	87.29	0.00e+00	1123.00
IUUC-Pno-095125	Phaeosphaeria nodorum	37.39	5.00e-42	165.00
IUUC-Pfo-096757	Poecilia formosa	78.92	0.00e+00	951.00
IUUC-Pab-097788	Pongo abelii	92.08	0.00e+00	814.00
IUUC-Pca-100145	Procavia capensis	76.22	0.00e+00	889.00
IUUC-Pva-102965	Pteropus vampyrus	86.14	0.00e+00	1090.00
IUUC-Pgr-103609	Puccinia graminis	30.86	2.00e-33	136.00
IUUC-Ptt-103865	Puccinia triticina	35.20	7.00e-34	139.00
IUUC-Pte-104095	Pyrenophora teres	35.24	2.00e-41	164.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	35.87	4.00e-41	163.00
IUUC-Rno-105125	Rattus norvegicus	89.07	0.00e+00	1159.00
IUUC-Sce-106192	Saccharomyces cerevisiae	29.28	5.00e-27	115.00
IUUC-Sha-107066	Sarcophilus harrisii	98.32	0.00e+00	1248.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	34.46	6.00e-42	165.00
IUUC-Spo-108220	Schizosaccharomyces pombe	29.97	5.00e-39	155.00
IUUC-Smo-109345	Selaginella moellendorffii	37.76	8.00e-21	94.40
IUUC-Stu-112464	Solanum tuberosum	45.31	3.00e-13	70.90
IUUC-Sar-113393	Sorex araneus	91.05	3.00e-105	375.00
IUUC-Sre-114986	Sporisorium reilianum	38.12	2.00e-42	167.00
IUUC-Tgu-117505	Taeniopygia guttata	84.39	0.00e+00	1055.00
IUUC-Tru-118494	Takifugu rubripes	79.26	0.00e+00	1022.00
IUUC-Tsy-119626	Tarsius syrichta	96.91	1.00e-52	201.00
IUUC-Tni-120174	Tetraodon nigroviridis	74.56	0.00e+00	1023.00
IUUC-Tre-122191	Trichoderma reesei	33.45	9.00e-40	158.00
IUUC-Tvi-122318	Trichoderma virens	32.98	1.00e-40	161.00
IUUC-Tme-126914	Tuber melanosporum	34.40	1.00e-43	171.00
IUUC-Ttr-129095	Tursiops truncatus	90.55	0.00e+00	1193.00
IUUC-Uma-129475	Ustilago maydis	36.61	3.00e-39	157.00
IUUC-Vda-129908	Verticillium dahliae	32.87	4.00e-35	143.00
IUUC-Xtr-131900	Xenopus tropicalis	80.77	0.00e+00	1056.00
IUUC-Xma-133124	Xiphophorus maculatus	78.48	0.00e+00	1004.00
IUUC-Yli-134682	Yarrowia lipolytica	32.37	1.00e-31	130.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence