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Tag Content
UUCD2 ID IUUC-Mcc-054676
UUCD1 version UUC-MaM-00126
Ensembl Protein ID ENSMMUP00000059041.1
UniProt Accession A0A1D5RFE7; A0A1D5RFE7_MACMU
Genbank Protein ID AFH34431.1; AFH34432.1
Protein Name E3 ubiquitin-protein ligase CBL
Genbank Nucleotide ID JSUE03013536; JU477628
Gene Name CBL
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000004761.3 ENSMMUT00000078411.1 ENSMMUP00000059041.1
ENSMMUG00000004761.3 ENSMMUT00000066609.1 ENSMMUP00000055380.1
ENSMMUG00000004761.3 ENSMMUT00000006725.3 ENSMMUP00000006328.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 3.60e-07 31.7 382 421
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl  w    + +s  + CP Cr
   Q: 382  CKICAENDKD-VKIEPCGHLMCTSCLTSW----Q-ESEGQGCPFCR 421
           99********.******************....5.555555****8 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MAGNVKKSSG AGGGGGSGGS GSGGLIGLMK DAFQPHHHHH HHHLSPHPPG TVDKKMVEKC 60
WKLMDKVVRL CQNPKLALKN SPPYILDLLP DTYQHLRTIL SRYEGKMETL GENEYFRVFM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-054676|E3,RING|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGCGGCCGG GAGAGGCCCC TCCTTCAAGC CCTGCTTCTC TCCCTCGCTC GCAGTCCAGC 60
CGAGCCGGCG GACCCGCCTG GGCTCCGACC CTGCCCAGGC CATGGCCGGC AACGTGAAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-054676|E3,RING|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3
PF00627--UBA
SMART

SM00184--RING
SM00165--UBA
Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0016874--F:ligase activity
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling
KEGG mcc:704311
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002357 Ailuropoda melanoleuca 91.30 0.00e+00 1474.00
IUUC-Apl-004041 Anas platyrhynchos 84.25 0.00e+00 1372.00
IUUC-Aca-004899 Anolis carolinensis 81.18 0.00e+00 1251.00
IUUC-Ame-010746 Astyanax mexicanus 59.03 2.00e-180 625.00
IUUC-Bta-012759 Bos taurus 91.47 0.00e+00 1522.00
IUUC-Cja-019207 Callithrix jacchus 97.36 0.00e+00 1620.00
IUUC-Cfa-020897 Canis familiaris 92.27 0.00e+00 1524.00
IUUC-Cpo-021453 Cavia porcellus 90.96 0.00e+00 1506.00
IUUC-Csa-023136 Chlorocebus sabaeus 99.89 0.00e+00 1637.00
IUUC-Cho-024282 Choloepus hoffmanni 85.24 0.00e+00 1254.00
IUUC-Cin-025574 Ciona intestinalis 71.54 1.00e-177 615.00
IUUC-Csv-025938 Ciona savignyi 69.87 7.00e-173 599.00
IUUC-Dre-027644 Danio rerio 68.76 0.00e+00 1038.00
IUUC-Dno-030025 Dasypus novemcinctus 92.50 0.00e+00 1475.00
IUUC-Dme-032213 Drosophila melanogaster 74.81 0.00e+00 644.00
IUUC-Ete-033118 Echinops telfairi 79.24 0.00e+00 811.00
IUUC-Eca-033900 Equus caballus 94.01 0.00e+00 1506.00
IUUC-Eeu-035142 Erinaceus europaeus 85.91 0.00e+00 958.00
IUUC-Fca-035455 Felis catus 91.40 0.00e+00 1502.00
IUUC-Fal-037182 Ficedula albicollis 96.75 0.00e+00 902.00
IUUC-Gmo-038698 Gadus morhua 87.30 0.00e+00 869.00
IUUC-Gga-040438 Gallus gallus 83.72 0.00e+00 1389.00
IUUC-Gac-042166 Gasterosteus aculeatus 76.28 0.00e+00 885.00
IUUC-Ggo-045618 Gorilla gorilla 98.24 0.00e+00 1635.00
IUUC-Hsa-046177 Homo sapiens 98.35 0.00e+00 1626.00
IUUC-Itr-048795 Ictidomys tridecemlineatus 96.47 0.00e+00 1013.00
IUUC-Lch-050095 Latimeria chalumnae 73.73 0.00e+00 1168.00
IUUC-Loc-052570 Lepisosteus oculatus 71.83 0.00e+00 1128.00
IUUC-Laf-054008 Loxodonta africana 90.27 0.00e+00 1525.00
IUUC-Mga-059239 Meleagris gallopavo 82.74 0.00e+00 1398.00
IUUC-Mmr-060907 Microcebus murinus 92.11 0.00e+00 1519.00
IUUC-Mdo-062595 Monodelphis domestica 87.95 0.00e+00 1405.00
IUUC-Mmu-063725 Mus musculus 90.84 0.00e+00 1568.00
IUUC-Mpu-066771 Mustela putorius furo 91.38 0.00e+00 1527.00
IUUC-Mlu-067206 Myotis lucifugus 76.55 0.00e+00 1089.00
IUUC-Nle-069285 Nomascus leucogenys 95.27 0.00e+00 1522.00
IUUC-Opr-071026 Ochotona princeps 92.65 0.00e+00 1489.00
IUUC-Ont-071954 Oreochromis niloticus 70.45 0.00e+00 1036.00
IUUC-Ocu-074657 Oryctolagus cuniculus 91.76 0.00e+00 1455.00
IUUC-Ola-087165 Oryzias latipes 67.08 0.00e+00 1058.00
IUUC-Oga-088198 Otolemur garnettii 83.12 0.00e+00 1333.00
IUUC-Oar-090258 Ovis aries 91.44 0.00e+00 1459.00
IUUC-Ptr-090710 Pan troglodytes 98.35 0.00e+00 1626.00
IUUC-Pan-092785 Papio anubis 99.78 0.00e+00 1635.00
IUUC-Pfo-096990 Poecilia formosa 90.16 0.00e+00 818.00
IUUC-Pab-098526 Pongo abelii 98.13 0.00e+00 1622.00
IUUC-Pca-100984 Procavia capensis 78.52 1.00e-169 590.00
IUUC-Pva-102352 Pteropus vampyrus 98.54 0.00e+00 902.00
IUUC-Rno-105876 Rattus norvegicus 90.19 0.00e+00 1544.00
IUUC-Sha-107588 Sarcophilus harrisii 85.84 0.00e+00 1217.00
IUUC-Sar-112959 Sorex araneus 88.24 0.00e+00 1419.00
IUUC-Ssc-115261 Sus scrofa 92.37 0.00e+00 1532.00
IUUC-Tgu-116580 Taeniopygia guttata 81.47 0.00e+00 1308.00
IUUC-Tru-118731 Takifugu rubripes 68.45 0.00e+00 1042.00
IUUC-Tsy-118982 Tarsius syrichta 87.41 0.00e+00 1061.00
IUUC-Tni-120725 Tetraodon nigroviridis 68.71 0.00e+00 1031.00
IUUC-Tbe-128018 Tupaia belangeri 95.60 0.00e+00 1164.00
IUUC-Ttr-128927 Tursiops truncatus 93.45 0.00e+00 1576.00
IUUC-Vpa-130369 Vicugna pacos 92.76 0.00e+00 1441.00
IUUC-Xtr-132474 Xenopus tropicalis 74.00 0.00e+00 1141.00
Created Date 25-Jun-2017

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