iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001802

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01112577

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000012941.1	ENSAMET00000014244.1	ENSAMEP00000013673.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-12	47.5	1087	1120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++ +t++   d t+ l+sG+ Dg i +WD+ tg
   Q: 1087 GHSGAITAVYI-DqTMvLASGGQDGAICLWDVLTG 1120
           8********88.446648*************9887 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MTLTERLREK ISQAFYNHGL LCASYPIPII LFTGLCILAC CCPLLKLPLP GTGPVEFTTP 60
VKDYSPPPAA PDHKPGEPSE RPEWYVGAPV AYIQQIFVKS SVSPWHRNLL AVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTGA CTGAAAGGCT GCGCGAGAAG ATATCTCAGG CCTTCTACAA CCATGGGCTG 60
CTCTGCGCAT CCTACCCCAT CCCTATCATC CTCTTCACGG GGCTCTGCAT CTTAGCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR027295--Quinoprotein_ADH-like_fam
IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003294	Anas platyrhynchos	83.90	0.00e+00	942.00
IUUC-Aca-004424	Anolis carolinensis	76.50	0.00e+00	870.00
IUUC-Bta-013478	Bos taurus	95.67	0.00e+00	1122.00
IUUC-Cel-018160	Caenorhabditis elegans	30.12	4.00e-65	243.00
IUUC-Cja-019123	Callithrix jacchus	91.02	0.00e+00	1044.00
IUUC-Cfa-021082	Canis familiaris	98.92	0.00e+00	1134.00
IUUC-Cpo-022477	Cavia porcellus	93.19	0.00e+00	1048.00
IUUC-Csa-023176	Chlorocebus sabaeus	89.32	0.00e+00	1025.00
IUUC-Cin-025490	Ciona intestinalis	41.79	8.00e-76	278.00
IUUC-Csv-026115	Ciona savignyi	39.16	2.00e-119	424.00
IUUC-Dre-028008	Danio rerio	73.19	0.00e+00	858.00
IUUC-Dno-028887	Dasypus novemcinctus	92.41	0.00e+00	1103.00
IUUC-Dor-030467	Dipodomys ordii	93.28	0.00e+00	877.00
IUUC-Dme-032087	Drosophila melanogaster	36.44	3.00e-96	347.00
IUUC-Ete-032372	Echinops telfairi	69.65	0.00e+00	733.00
IUUC-Eca-033896	Equus caballus	96.28	0.00e+00	1135.00
IUUC-Eeu-035099	Erinaceus europaeus	85.91	0.00e+00	942.00
IUUC-Fca-035616	Felis catus	87.22	0.00e+00	1135.00
IUUC-Fal-037231	Ficedula albicollis	80.79	0.00e+00	915.00
IUUC-Gmo-039439	Gadus morhua	65.90	0.00e+00	720.00
IUUC-Gac-041516	Gasterosteus aculeatus	72.96	0.00e+00	828.00
IUUC-Hsa-046674	Homo sapiens	94.43	0.00e+00	1110.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	95.82	0.00e+00	1128.00
IUUC-Lch-049689	Latimeria chalumnae	75.46	0.00e+00	871.00
IUUC-Loc-051906	Lepisosteus oculatus	88.59	4.00e-76	276.00
IUUC-Laf-053795	Loxodonta africana	94.74	0.00e+00	1122.00
IUUC-Mcc-055502	Macaca mulatta	95.20	0.00e+00	1122.00
IUUC-Mga-059805	Meleagris gallopavo	84.98	0.00e+00	960.00
IUUC-Mmr-060997	Microcebus murinus	95.67	0.00e+00	1122.00
IUUC-Mdo-062940	Monodelphis domestica	86.41	0.00e+00	1011.00
IUUC-Mmu-063255	Mus musculus	95.36	0.00e+00	1119.00
IUUC-Mpu-066158	Mustela putorius furo	97.83	0.00e+00	1148.00
IUUC-Mlu-067201	Myotis lucifugus	89.52	0.00e+00	1028.00
IUUC-Nle-069145	Nomascus leucogenys	94.89	0.00e+00	1113.00
IUUC-Opr-070797	Ochotona princeps	84.98	0.00e+00	944.00
IUUC-Ont-071553	Oreochromis niloticus	72.70	0.00e+00	845.00
IUUC-Ocu-074598	Oryctolagus cuniculus	95.20	0.00e+00	1089.00
IUUC-Ola-086650	Oryzias latipes	84.68	1.00e-113	401.00
IUUC-Oar-089287	Ovis aries	87.63	0.00e+00	1006.00
IUUC-Pan-092004	Papio anubis	95.20	0.00e+00	1122.00
IUUC-Psi-093028	Pelodiscus sinensis	81.06	0.00e+00	972.00
IUUC-Pma-094145	Petromyzon marinus	61.69	0.00e+00	744.00
IUUC-Pfo-096320	Poecilia formosa	72.77	0.00e+00	842.00
IUUC-Pab-097862	Pongo abelii	94.74	0.00e+00	1115.00
IUUC-Pca-100862	Procavia capensis	74.93	0.00e+00	907.00
IUUC-Pva-103050	Pteropus vampyrus	94.58	0.00e+00	1075.00
IUUC-Rno-105852	Rattus norvegicus	95.20	0.00e+00	1120.00
IUUC-Sha-107312	Sarcophilus harrisii	85.65	0.00e+00	1025.00
IUUC-Sar-113311	Sorex araneus	88.94	0.00e+00	740.00
IUUC-Ssc-116356	Sus scrofa	96.90	0.00e+00	1168.00
IUUC-Tgu-116896	Taeniopygia guttata	77.37	9.00e-88	318.00
IUUC-Tru-118197	Takifugu rubripes	74.35	0.00e+00	843.00
IUUC-Tni-119823	Tetraodon nigroviridis	70.14	0.00e+00	838.00
IUUC-Ttr-129164	Tursiops truncatus	95.36	0.00e+00	1118.00
IUUC-Xtr-132819	Xenopus tropicalis	74.48	0.00e+00	871.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence