iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026115

UUCD1 version

UUC-CiS-00276

Ensembl Protein ID

ENSCSAVP00000012866.1

UniProt Accession

H2Z5K4; H2Z5K4_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000007555.1	ENSCSAVT00000013015.1	ENSCSAVP00000012866.1
ENSCSAVG00000007555.1	ENSCSAVT00000013016.1	ENSCSAVP00000012867.1
ENSCSAVG00000007555.1	ENSCSAVT00000013017.1	ENSCSAVP00000012868.1
ENSCSAVG00000007555.1	ENSCSAVT00000013018.1	ENSCSAVP00000012869.1
ENSCSAVG00000007555.1	ENSCSAVT00000013019.1	ENSCSAVP00000012870.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-15	56.5	1052	1089

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgvllk 37
           gHt+++t l+    s    vsGs Dgt+++WDl tg +l+
   Q: 1052 GHTGPITVLHVdkvS--GAVSGSSDGTVRLWDLLTGLCLH 1089
           8*********94332..27******************997 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

YTMKTHQENI ERAFYGYGIF ASRHPVIMIL FSAAMVLLCC YPLLNLPLPG SEPTKFDTLT 60
KDLKQCYGDG SCGNFLNDGV TIKVPDWLDS TYHAAFVQQF LVKSIVTPWP PQGMYKSDAY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAATACACAA TGAAAACTCA CCAGGAAAAC ATTGAACGTG CATTTTATGG TTACGGTATC 60
TTTGCGTCCA GACACCCTGT GATTATGATT CTTTTTTCTG CTGCTATGGT GTTACTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	39.16	1.00e-111	396.00
IUUC-Apl-003294	Anas platyrhynchos	38.42	5.00e-138	484.00
IUUC-Aca-004424	Anolis carolinensis	37.48	3.00e-125	441.00
IUUC-Bta-013478	Bos taurus	37.28	3.00e-132	465.00
IUUC-Cel-018160	Caenorhabditis elegans	26.28	2.00e-66	246.00
IUUC-Cja-019123	Callithrix jacchus	36.10	3.00e-118	418.00
IUUC-Cfa-021082	Canis familiaris	36.99	7.00e-126	443.00
IUUC-Cpo-022477	Cavia porcellus	40.20	4.00e-123	434.00
IUUC-Csa-023176	Chlorocebus sabaeus	38.30	3.00e-134	471.00
IUUC-Cin-025490	Ciona intestinalis	71.24	0.00e+00	1303.00
IUUC-Dre-028008	Danio rerio	38.96	4.00e-140	491.00
IUUC-Dno-028887	Dasypus novemcinctus	40.00	5.00e-127	447.00
IUUC-Dor-030467	Dipodomys ordii	41.28	5.00e-95	341.00
IUUC-Dme-032087	Drosophila melanogaster	30.14	5.00e-106	377.00
IUUC-Ete-032372	Echinops telfairi	39.30	3.00e-59	222.00
IUUC-Eca-033896	Equus caballus	36.99	2.00e-130	458.00
IUUC-Eeu-035099	Erinaceus europaeus	38.15	1.00e-87	317.00
IUUC-Fca-035616	Felis catus	39.10	3.00e-112	398.00
IUUC-Fal-037231	Ficedula albicollis	37.33	3.00e-130	458.00
IUUC-Gmo-039439	Gadus morhua	42.53	1.00e-99	356.00
IUUC-Gac-041516	Gasterosteus aculeatus	38.10	1.00e-132	466.00
IUUC-Hsa-046674	Homo sapiens	37.68	3.00e-133	468.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	37.42	2.00e-134	472.00
IUUC-Lch-049689	Latimeria chalumnae	37.18	1.00e-130	459.00
IUUC-Loc-052417	Lepisosteus oculatus	29.90	9.00e-27	113.00
IUUC-Laf-053795	Loxodonta africana	37.81	1.00e-132	466.00
IUUC-Mcc-055502	Macaca mulatta	37.44	1.00e-133	469.00
IUUC-Mga-059805	Meleagris gallopavo	38.44	8.00e-134	470.00
IUUC-Mmr-060997	Microcebus murinus	37.38	6.00e-133	467.00
IUUC-Mdo-062940	Monodelphis domestica	37.91	2.00e-130	459.00
IUUC-Mmu-063255	Mus musculus	36.57	7.00e-132	463.00
IUUC-Mpu-066158	Mustela putorius furo	36.85	9.00e-130	456.00
IUUC-Mlu-067201	Myotis lucifugus	37.32	3.00e-122	431.00
IUUC-Nle-069145	Nomascus leucogenys	37.55	8.00e-127	446.00
IUUC-Opr-070797	Ochotona princeps	37.21	2.00e-77	283.00
IUUC-Ont-071553	Oreochromis niloticus	38.99	2.00e-138	485.00
IUUC-Ocu-074598	Oryctolagus cuniculus	36.41	4.00e-129	454.00
IUUC-Ola-086650	Oryzias latipes	39.46	2.00e-43	167.00
IUUC-Oar-089287	Ovis aries	40.24	9.00e-121	426.00
IUUC-Pan-092004	Papio anubis	37.44	2.00e-133	469.00
IUUC-Psi-093028	Pelodiscus sinensis	38.17	3.00e-136	478.00
IUUC-Pma-094145	Petromyzon marinus	35.31	1.00e-123	436.00
IUUC-Pfo-096320	Poecilia formosa	38.88	2.00e-138	485.00
IUUC-Pab-097862	Pongo abelii	37.56	4.00e-134	471.00
IUUC-Pca-100862	Procavia capensis	40.08	9.00e-75	273.00
IUUC-Pva-103050	Pteropus vampyrus	37.11	4.00e-124	437.00
IUUC-Rno-105852	Rattus norvegicus	36.62	1.00e-131	462.00
IUUC-Sha-107312	Sarcophilus harrisii	37.87	1.00e-130	459.00
IUUC-Sar-113311	Sorex araneus	39.62	1.00e-60	227.00
IUUC-Ssc-116356	Sus scrofa	37.01	8.00e-134	470.00
IUUC-Tgu-116896	Taeniopygia guttata	39.15	5.00e-27	115.00
IUUC-Tru-118197	Takifugu rubripes	38.70	5.00e-137	480.00
IUUC-Tni-119823	Tetraodon nigroviridis	38.39	4.00e-139	488.00
IUUC-Ttr-129164	Tursiops truncatus	37.35	2.00e-130	459.00
IUUC-Xtr-132819	Xenopus tropicalis	36.19	5.00e-130	457.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence