iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088960

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03029819

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000009149.2	ENSOGAT00000009160.2	ENSOGAP00000008212.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.50e-78	262.8	48	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++k++       +  +lq+lf++l+  +++a s+ +l+++++++++e  +
   Q: 48   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGLFEDKDKPDakvrVIPLQLQRLFAQLLLLDQEAASTADLTDSFGWTSNE--E 134
           9*****************************88888876554332223455899*******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+nvs+++e+fldl+++
   Q: 135  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTTVNQIICKECKNVSEKQEDFLDLTVA 197
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L +++++ee ++++n y+c +c+++++a k+ kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+p
   Q: 198  VKNVS-----GLEDALwNMYVEEEVFDCDNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKP 281
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++e ++  +++Y+L++v++H+G++ +GHY++y+k+                                                   
   Q: 282  FCEQSELDDL-EYIYDLFSVIIHKGGCYGGHYHVYIKDvdhlgnwqfqeenckpdvnlkdlqnegeiddplvilkaillqeennlitvd 369
           ****999987.9***************************************************************************** PP
   S: 302  ...............................................................................ekgk....Wl 307
                                                                                          +       W+
   Q: 370  qlgqkllkrigiswnkkyrkqhgplrkflqlhsqifllssdestvsllkncslqaesdfqrndqqifktltsetlglndS--AscphWF 456
           *********************************************************99999999999998888887541..24577** PP
   S: 308  lfdDskVtevkeeevleetg..staYvlfYkr 337
            ++DskV+++ke++++++ +  ++aY+lfY++
   Q: 457  DINDSKVQPIKEKDIEQQFQgkESAYMLFYRK 488
           *****************9889*********98 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

VEFSFTMFGD LFEEDYSNVS NNQYGKGKKL KTKVLEPPAP REFTNLSGIR NQGGTCYLNS 60
LLQTLHFTPE FREALFSLGP EELGLFEDKD KPDAKVRVIP LQLQRLFAQL LLLDQEAAST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACATTCCGAA GACCCGCCCT TGCCAACATG GCGGCGCCCA GTTGGGGCGG GTTCATCAGC 60
TGCGCGTTTT GGCCGGGGCC GGGGTCTGGG CTCTAGGCAG TAAGTGGGGC TGGCCGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	83.46	0.00e+00	1927.00
IUUC-Apl-004105	Anas platyrhynchos	64.22	0.00e+00	1544.00
IUUC-Aca-004715	Anolis carolinensis	62.19	0.00e+00	1478.00
IUUC-Ame-011073	Astyanax mexicanus	47.68	0.00e+00	1026.00
IUUC-Bta-012487	Bos taurus	82.30	0.00e+00	1995.00
IUUC-Cja-018937	Callithrix jacchus	86.35	0.00e+00	2108.00
IUUC-Cfa-020645	Canis familiaris	78.43	0.00e+00	1238.00
IUUC-Cpo-022160	Cavia porcellus	81.02	0.00e+00	1983.00
IUUC-Csa-023078	Chlorocebus sabaeus	85.93	0.00e+00	2133.00
IUUC-Cho-025013	Choloepus hoffmanni	64.98	0.00e+00	803.00
IUUC-Csv-026193	Ciona savignyi	56.03	2.00e-58	218.00
IUUC-Dre-027416	Danio rerio	49.42	0.00e+00	1140.00
IUUC-Dno-029639	Dasypus novemcinctus	80.73	0.00e+00	1675.00
IUUC-Dor-030624	Dipodomys ordii	90.03	3.00e-153	536.00
IUUC-Ete-032626	Echinops telfairi	63.79	0.00e+00	736.00
IUUC-Eca-034208	Equus caballus	83.83	0.00e+00	2060.00
IUUC-Eeu-035340	Erinaceus europaeus	45.68	5.00e-91	329.00
IUUC-Fca-035886	Felis catus	70.57	0.00e+00	760.00
IUUC-Fal-036925	Ficedula albicollis	64.13	0.00e+00	1452.00
IUUC-Gmo-038597	Gadus morhua	49.42	0.00e+00	827.00
IUUC-Gga-041171	Gallus gallus	64.16	0.00e+00	1537.00
IUUC-Gac-041362	Gasterosteus aculeatus	44.28	0.00e+00	949.00
IUUC-Ggo-045069	Gorilla gorilla	84.64	0.00e+00	1920.00
IUUC-Hsa-046715	Homo sapiens	86.81	0.00e+00	2130.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	81.45	0.00e+00	1961.00
IUUC-Lch-050182	Latimeria chalumnae	51.22	0.00e+00	1129.00
IUUC-Loc-052705	Lepisosteus oculatus	53.91	0.00e+00	1262.00
IUUC-Laf-054132	Loxodonta africana	82.05	0.00e+00	2044.00
IUUC-Mcc-055734	Macaca mulatta	86.24	0.00e+00	2145.00
IUUC-Meu-056135	Macropus eugenii	84.98	6.00e-114	405.00
IUUC-Mga-060092	Meleagris gallopavo	63.61	0.00e+00	1510.00
IUUC-Mmr-061546	Microcebus murinus	84.81	0.00e+00	2085.00
IUUC-Mdo-061935	Monodelphis domestica	62.04	0.00e+00	1492.00
IUUC-Mmu-063630	Mus musculus	79.06	0.00e+00	1964.00
IUUC-Mpu-066579	Mustela putorius furo	80.82	0.00e+00	2024.00
IUUC-Mlu-068034	Myotis lucifugus	83.51	0.00e+00	1992.00
IUUC-Nle-069082	Nomascus leucogenys	84.41	0.00e+00	1747.00
IUUC-Opr-070953	Ochotona princeps	71.51	0.00e+00	968.00
IUUC-Ont-072435	Oreochromis niloticus	46.77	0.00e+00	1092.00
IUUC-Oan-073339	Ornithorhynchus anatinus	67.09	0.00e+00	1570.00
IUUC-Ocu-073760	Oryctolagus cuniculus	81.57	0.00e+00	2004.00
IUUC-Ola-087015	Oryzias latipes	46.08	0.00e+00	929.00
IUUC-Oar-089853	Ovis aries	82.81	0.00e+00	2025.00
IUUC-Ptr-091093	Pan troglodytes	86.48	0.00e+00	2123.00
IUUC-Pan-091962	Papio anubis	85.30	0.00e+00	2116.00
IUUC-Psi-093691	Pelodiscus sinensis	66.16	0.00e+00	1599.00
IUUC-Pma-094428	Petromyzon marinus	65.47	3.00e-91	328.00
IUUC-Pfo-096983	Poecilia formosa	47.82	0.00e+00	1025.00
IUUC-Pab-097860	Pongo abelii	85.62	0.00e+00	1955.00
IUUC-Pca-100514	Procavia capensis	78.88	0.00e+00	657.00
IUUC-Pva-102771	Pteropus vampyrus	82.42	0.00e+00	1885.00
IUUC-Rno-105405	Rattus norvegicus	78.09	0.00e+00	1902.00
IUUC-Sha-107376	Sarcophilus harrisii	64.18	0.00e+00	1483.00
IUUC-Ssc-115819	Sus scrofa	78.17	0.00e+00	1363.00
IUUC-Tgu-117262	Taeniopygia guttata	62.74	0.00e+00	1509.00
IUUC-Tru-117601	Takifugu rubripes	47.22	0.00e+00	1077.00
IUUC-Tsy-118996	Tarsius syrichta	75.36	0.00e+00	1627.00
IUUC-Tni-120682	Tetraodon nigroviridis	43.37	0.00e+00	868.00
IUUC-Tbe-127616	Tupaia belangeri	63.67	0.00e+00	1244.00
IUUC-Ttr-129075	Tursiops truncatus	80.58	0.00e+00	1883.00
IUUC-Vpa-130108	Vicugna pacos	83.47	0.00e+00	1818.00
IUUC-Xtr-132623	Xenopus tropicalis	52.49	0.00e+00	1206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence