iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
iRefIndex	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/ULP	7.30e-51	172.8	1328	1635

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/ULP

   S: 2    svtnedlkcLeegeflnDviidfylkylvleklkkekverihifssffykklkqkerr.............rvktwtrkvdlfekdlifvpineaa 84
           ++++ed+ cL+++++lnD iidfyl +l +  + + + er+hifs+ffyk+l++  r              rv++wt+ vd+f+kd+i+vpine++
   Q: 1328 CIRMEDFVCLTKESYLNDIIIDFYLLWLRNTLIPEPQRERTHIFSTFFYKRLTTLTRPadmkqtaaqkrhaRVQKWTKGVDIFDKDFIIVPINEQS 1423
           799***********************9999999********************9776677999********************************* PP
   S: 85   HWslavvcf....................................................................................... 93
           HW+la++c                                                                                        
   Q: 1424 HWFLAIICYpnlkgpvtfdtnqpvepqqlkrprgkkvalqignttitpltkraeggqlpaaltaenvcriaddeserdeaegdesdmasedsensn 1519
           ************************************************************************************************ PP
   S: 94   .........................................kkksilllDSlrgasksnvvkklreylev..evkkk..skrefskeklkgsnpkv 144
                                                    k++ il++DSl gas+s+vv +lr+yl+    vkk   + + f+k+++ g+++kv
   Q: 1520 sakepaatptsttastpslsssqptatgparniasddvpavKQPLILIFDSLAGASRSRVVATLRDYLTCeyRVKKPdaQAHVFNKDNMPGHCVKV 1615
           ********************************************************************9954455431145679************ PP
   S: 145  pqQkNssDCGvyvlqyvesl 164
           pqQ+N+ DCG+y+lqyve++
   Q: 1616 PQQNNFTDCGLYLLQYVEQF 1635
           *****************987 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MEQYIVPLEE PVYSDLQVVQ VPQDEVGSLV LQDDQQLVFN DQQQVVYQTT APAQYQQPQQ 60
SAAPTYHIIG GDDLAHQQQQ HQQQQQQQQQ QQQQQQQPQQ QHQQQQQQVV MHHQQHQVQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTCTTCTT CTTCTTCTTC TTCCTCACCC AATTCGCCAG AGCGCGCAGC AAACAACAAA 60
ACACATAGTG CTCAAAACCG CGATATCAAC GGTCGCTAAA AATCGTTATC AATCGCCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR003653--Peptidase_C48_C
IPR008917--TF_DNA-bd
IPR015943--WD40/YVTN_repeat-like_dom

PROSITE

PS50600--ULP_PROTEASE

Pfam

PF02902--Peptidase_C48

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0005634--C:nucleus
GO:0004872--F:receptor activity
GO:0016929--F:SUMO-specific protease activity
GO:0007411--P:axon guidance
GO:0021952--P:central nervous system projection neuron axonogenesis
GO:0060997--P:dendritic spine morphogenesis
GO:0060548--P:negative regulation of cell death
GO:0016926--P:protein desumoylation
GO:0002224--P:toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003445	Anas platyrhynchos	29.60	3.00e-34	140.00
IUUC-Acl-008018	Aspergillus clavatus	38.10	2.00e-18	87.80
IUUC-Afl-008482	Aspergillus flavus	36.29	2.00e-18	87.40
IUUC-Afu-008974	Aspergillus fumigatus	33.93	5.00e-19	88.60
IUUC-Ani-009366	Aspergillus nidulans	38.40	3.00e-18	87.00
IUUC-Ame-011446	Astyanax mexicanus	33.61	5.00e-51	194.00
IUUC-Bci-013906	Botrytis cinerea	36.84	2.00e-18	87.80
IUUC-Cho-024942	Choloepus hoffmanni	47.37	8.00e-23	102.00
IUUC-Cin-025522	Ciona intestinalis	37.20	2.00e-61	228.00
IUUC-Csv-025934	Ciona savignyi	49.66	1.00e-35	142.00
IUUC-Dse-031477	Dothistroma septosporum	30.43	5.00e-11	63.20
IUUC-Fal-037063	Ficedula albicollis	30.43	2.00e-34	141.00
IUUC-Fox-038045	Fusarium oxysporum	28.45	9.00e-24	105.00
IUUC-Ggr-039780	Gaeumannomyces graminis	39.25	4.00e-17	83.20
IUUC-Gga-040954	Gallus gallus	30.26	4.00e-34	139.00
IUUC-Lch-050229	Latimeria chalumnae	35.39	4.00e-44	172.00
IUUC-Loc-052810	Lepisosteus oculatus	33.90	2.00e-48	187.00
IUUC-Lma-053172	Leptosphaeria maculans	41.38	5.00e-22	100.00
IUUC-Mor-057033	Magnaporthe oryzae	25.22	2.00e-23	103.00
IUUC-Mpo-057440	Magnaporthe poae	42.06	3.00e-18	86.70
IUUC-Mvi-060469	Microbotryum violaceum	35.51	5.00e-17	83.60
IUUC-Mdo-062682	Monodelphis domestica	29.24	4.00e-36	146.00
IUUC-Nfi-068345	Neosartorya fischeri	38.89	3.00e-19	90.50
IUUC-Ncr-068866	Neurospora crassa	25.90	2.00e-21	97.80
IUUC-Oan-073177	Ornithorhynchus anatinus	28.99	1.00e-32	135.00
IUUC-Ola-086425	Oryzias latipes	49.63	9.00e-32	130.00
IUUC-Psi-093754	Pelodiscus sinensis	29.24	4.00e-33	136.00
IUUC-Pno-094801	Phaeosphaeria nodorum	28.32	6.00e-32	132.00
IUUC-Pfo-096310	Poecilia formosa	28.77	6.00e-34	138.00
IUUC-Pgr-103328	Puccinia graminis	25.75	2.00e-25	110.00
IUUC-Pte-104039	Pyrenophora teres	26.39	5.00e-31	129.00
IUUC-Pyt-104790	Pyrenophora triticirepentis	37.50	2.00e-18	86.70
IUUC-Sha-106934	Sarcophilus harrisii	29.53	2.00e-36	147.00
IUUC-Ssl-108654	Sclerotinia sclerotiorum	42.35	4.00e-14	72.40
IUUC-Sre-115211	Sporisorium reilianum	33.06	2.00e-18	87.80
IUUC-Tgu-116654	Taeniopygia guttata	29.74	4.00e-36	145.00
IUUC-Tvi-122488	Trichoderma virens	36.22	3.00e-19	90.10
IUUC-Uma-129452	Ustilago maydis	32.35	1.00e-18	88.20
IUUC-Vda-129950	Verticillium dahliae	36.97	2.00e-17	84.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence