iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID	iRefIndex	HINT
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	8.50e-18	64.8	32	138
E2/UEV	1.80e-64	216.3	4	145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E2/UBC

   S: 16   gisakpvdesd..ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsvesv 101
           ++s +++d++d  lt+w  +i+Gp++t+Ye+++++l+ie+ ++YP  PP+v+f+t++    v+++ G v         kW+  +s++ +
   Q: 32   TVSWGLEDDEDmtLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTRVNMSGVSSSnGVVDPRATAVLAKWQNSHSIKVI 120
           456667777776689******************************************999999887999766665568*********** PP
   S: 102  llsiqsll.aepnpespl 118
           l ++ +l+ ++ n++ p+
   Q: 121  LQELRRLMmSKENMKLPQ 138
           ******996667777665 PP

E2/UEV

   S: 4    eselkvvvprnfrlleeleegekglgdgtvsygldDgddilllsltgtIigpertayegrIyqlklfvgkkYPekPPtvrfsskinmae 92
           ++++ v+vprnfrlleeleeg+kg+gdgtvs+gl+D++d++l+++tg+Iigp+rt ye+rIy+lk+++g+kYPe+PP vrf++++nm++
   Q: 4    TTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTRVNMSG 92
           67899************************************************************************************ PP
   S: 93   vndsnGvvdpralpvLanWkreysievvlvqlkkellskenrklqqPpeGnlf 145
           v +snGvvdpra +vLa+W+++ si+v+l++l++ ++sken+kl+qPpeG+++
   Q: 93   VSSSNGVVDPRATAVLAKWQNSHSIKVILQELRRLMMSKENMKLPQPPEGQCY 145
           ***************************************************98 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAATTGSGVK VPRNFRLLEE LEEGQKGVGD GTVSWGLEDD EDMTLTRWTG MIIGPPRTIY 60
ENRIYSLKIE CGPKYPEAPP SVRFVTRVNM SGVSSSNGVV DPRATAVLAK WQNSHSIKVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGTGAAGA AGGGGCCGGC CTTCGAGCGA CAGCGACGCA AGATGGCAGC CACCACAGGC 60
TCGGGTGAGC GGGGGCGCCG GGCGTGCTGG CAGACGGAGC GCGGGCTGCT TGGGCTGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination

KEGG

rno:100912618; rno:296390; rno:679539

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000910	Aegilops tauschii	52.11	1.00e-39	154.00
IUUC-Aml-001242	Ailuropoda melanoleuca	92.91	4.00e-71	261.00
IUUC-Atr-003005	Amborella trichopoda	51.75	2.00e-38	150.00
IUUC-Apl-003600	Anas platyrhynchos	93.57	4.00e-71	259.00
IUUC-Aca-005104	Anolis carolinensis	92.14	8.00e-75	271.00
IUUC-Aly-005402	Arabidopsis lyrata	55.32	5.00e-40	156.00
IUUC-Ath-007596	Arabidopsis thaliana	52.05	2.00e-38	150.00
IUUC-Ago-007810	Ashbya gossypii	52.21	2.00e-34	137.00
IUUC-Acl-008375	Aspergillus clavatus	50.72	6.00e-33	132.00
IUUC-Afl-008598	Aspergillus flavus	51.49	6.00e-34	135.00
IUUC-Afu-008838	Aspergillus fumigatus	51.11	2.00e-34	137.00
IUUC-Ani-009325	Aspergillus nidulans	50.00	1.00e-35	141.00
IUUC-Ang-009631	Aspergillus niger	52.17	5.00e-35	139.00
IUUC-Aor-010051	Aspergillus oryzae	51.49	6.00e-34	135.00
IUUC-Ame-010710	Astyanax mexicanus	84.35	5.00e-73	266.00
IUUC-Bta-013403	Bos taurus	93.88	3.00e-75	273.00
IUUC-Bci-013649	Botrytis cinerea	50.72	2.00e-33	134.00
IUUC-Bdi-014636	Brachypodium distachyon	52.24	1.00e-37	148.00
IUUC-Bol-015323	Brassica oleracea	53.85	8.00e-41	159.00
IUUC-Bra-018041	Brassica rapa	53.85	8.00e-41	159.00
IUUC-Cja-019316	Callithrix jacchus	93.88	3.00e-75	273.00
IUUC-Cfa-021118	Canis familiaris	93.57	3.00e-71	260.00
IUUC-Cre-022629	Chlamydomonas reinhardtii	50.36	8.00e-38	149.00
IUUC-Csa-024275	Chlorocebus sabaeus	92.91	5.00e-71	261.00
IUUC-Cin-025219	Ciona intestinalis	49.04	6.00e-26	109.00
IUUC-Cgl-026596	Colletotrichum gloeosporioides	54.35	3.00e-37	147.00
IUUC-Cme-027257	Cyanidioschyzon merolae	55.47	7.00e-29	119.00
IUUC-Dre-028019	Danio rerio	83.67	7.00e-73	265.00
IUUC-Dno-029762	Dasypus novemcinctus	93.62	1.00e-71	261.00
IUUC-Dme-031635	Drosophila melanogaster	64.83	4.00e-58	216.00
IUUC-Ete-033017	Echinops telfairi	85.82	2.00e-67	249.00
IUUC-Eca-034422	Equus caballus	93.53	2.00e-70	257.00
IUUC-Eeu-035327	Erinaceus europaeus	92.91	2.00e-71	262.00
IUUC-Fal-037350	Ficedula albicollis	90.48	5.00e-72	262.00
IUUC-Fox-037803	Fusarium oxysporum	52.17	3.00e-37	147.00
IUUC-Fso-038147	Fusarium solani	54.68	2.00e-38	150.00
IUUC-Gmo-039237	Gadus morhua	76.87	9.00e-68	248.00
IUUC-Gma-043736	Glycine max	54.29	7.00e-44	169.00
IUUC-Hsa-045659	Homo sapiens	93.88	3.00e-75	273.00
IUUC-Hvu-047368	Hordeum vulgare	52.24	1.00e-37	148.00
IUUC-Itr-048139	Ictidomys tridecemlineatus	93.57	4.00e-71	259.00
IUUC-Lch-050494	Latimeria chalumnae	82.14	4.00e-69	253.00
IUUC-Laf-054176	Loxodonta africana	93.88	3.00e-75	273.00
IUUC-Mcc-055326	Macaca mulatta	89.80	1.00e-71	261.00
IUUC-Meu-056842	Macropus eugenii	80.00	4.00e-34	139.00
IUUC-Mtr-058655	Medicago truncatula	54.48	1.00e-39	155.00
IUUC-Mga-059951	Meleagris gallopavo	92.91	3.00e-71	260.00
IUUC-Mmr-061374	Microcebus murinus	89.12	5.00e-63	232.00
IUUC-Mmu-063234	Mus musculus	99.29	5.00e-72	264.00
IUUC-Mac-065220	Musa acuminata	51.72	8.00e-40	155.00
IUUC-Mpu-065775	Mustela putorius furo	93.88	3.00e-75	273.00
IUUC-Mlu-067269	Myotis lucifugus	89.04	9.00e-69	252.00
IUUC-Nfi-068400	Neosartorya fischeri	46.32	1.00e-26	111.00
IUUC-Nle-069245	Nomascus leucogenys	93.88	3.00e-75	273.00
IUUC-Opr-070859	Ochotona princeps	80.85	2.00e-59	222.00
IUUC-Ocu-074447	Oryctolagus cuniculus	91.43	3.00e-70	256.00
IUUC-Oba-075005	Oryza barthii	53.73	8.00e-38	149.00
IUUC-Obr-076191	Oryza brachyantha	53.47	2.00e-40	157.00
IUUC-Ogl-077233	Oryza glaberrima	53.73	8.00e-38	149.00
IUUC-Ogu-078374	Oryza glumaepatula	53.73	8.00e-38	149.00
IUUC-Oin-079721	Oryza indica	53.73	8.00e-38	149.00
IUUC-Ome-081761	Oryza meridionalis	53.73	5.00e-38	150.00
IUUC-Oni-082346	Oryza nivara	53.73	8.00e-38	149.00
IUUC-Opu-083148	Oryza punctata	53.73	8.00e-38	149.00
IUUC-Oru-084359	Oryza rufipogon	53.73	8.00e-38	149.00
IUUC-Osa-085664	Oryza sativa	53.73	8.00e-38	149.00
IUUC-Oga-087972	Otolemur garnettii	93.57	4.00e-71	259.00
IUUC-Oar-090166	Ovis aries	92.91	2.00e-71	262.00
IUUC-Ptr-090866	Pan troglodytes	93.88	3.00e-75	273.00
IUUC-Pan-092804	Papio anubis	91.16	1.00e-72	265.00
IUUC-Pma-094142	Petromyzon marinus	85.71	1.00e-21	94.00
IUUC-Ppa-095500	Physcomitrella patens	53.90	7.00e-41	159.00
IUUC-Pab-098403	Pongo abelii	92.91	2.00e-71	262.00
IUUC-Pop-099786	Populus trichocarpa	53.15	5.00e-40	156.00
IUUC-Pca-100723	Procavia capensis	92.91	2.00e-71	262.00
IUUC-Ppe-101725	Prunus persica	55.00	7.00e-40	156.00
IUUC-Pva-102393	Pteropus vampyrus	91.49	2.00e-75	275.00
IUUC-Sha-107363	Sarcophilus harrisii	89.80	1.00e-71	261.00
IUUC-Ssl-108493	Sclerotinia sclerotiorum	50.70	1.00e-34	138.00
IUUC-Smo-109006	Selaginella moellendorffii	46.72	6.00e-30	122.00
IUUC-Sit-110302	Setaria italica	54.17	2.00e-41	160.00
IUUC-Sly-111205	Solanum lycopersicum	54.55	6.00e-41	159.00
IUUC-Stu-112459	Solanum tuberosum	53.85	2.00e-40	157.00
IUUC-Sbi-114210	Sorghum bicolor	53.47	7.00e-41	159.00
IUUC-Sre-114909	Sporisorium reilianum	51.09	1.00e-33	135.00
IUUC-Ssc-115939	Sus scrofa	93.88	3.00e-75	273.00
IUUC-Tgu-117289	Taeniopygia guttata	92.91	1.00e-71	261.00
IUUC-Tsy-119103	Tarsius syrichta	93.55	1.00e-48	185.00
IUUC-Tca-121025	Theobroma cacao	56.43	1.00e-40	159.00
IUUC-Tvi-122622	Trichoderma virens	55.07	1.00e-37	148.00
IUUC-Tae-123220	Triticum aestivum	52.24	1.00e-37	148.00
IUUC-Tur-126236	Triticum urartu	51.82	3.00e-38	150.00
IUUC-Tbe-128105	Tupaia belangeri	91.37	2.00e-73	269.00
IUUC-Ttr-128790	Tursiops truncatus	92.91	3.00e-71	262.00
IUUC-Uma-129419	Ustilago maydis	52.55	2.00e-34	137.00
IUUC-Vda-129776	Verticillium dahliae	52.86	4.00e-37	146.00
IUUC-Vpa-130575	Vicugna pacos	92.81	3.00e-69	254.00
IUUC-Vvi-130831	Vitis vinifera	56.43	6.00e-42	162.00
IUUC-Xtr-132359	Xenopus tropicalis	90.48	7.00e-72	262.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence