iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004348

Ensembl Protein ID

ENSACAP00000005524.3

UniProt Accession

G1KEG4; G1KEG4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000005460.3	ENSACAT00000005645.3	ENSACAP00000005524.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-31	106.4	46	83
UBD/Beta-Prp	1.10e-50	172.5	31	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  +  ++ +GsdD+ +k+W+++ g+ll
   Q: 46   GHLSAVYCVAFdRTgQRIFTGSDDCLVKIWSTHNGRLL 83
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 77   kvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWd 165
            v+ ++  k+ + + gh + v++++f+++g+++ +Gs+d  +++w +++g  l  tl+gh++ ++ ++v+ ++ ++++Gs D+++r+W+
   Q: 31   PVNMYQHIKMHRRILGHLSAVYCVAFDRTGQRIFTGSDDCLVKIWSTHNGRLLA-TLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWC 118
           577788888889999**************************************9.********************************** PP
   S: 166  lktgkllrtltgghtdsvyslsfdsng....kelvsgsldgtvklwdlqt 211
           l+t   l  l+g ht+s++sl+f++      +++vs + dgtv +w+  t
   Q: 119  LRTCAPLAVLQG-HTGSITSLQFSPLVkdttRYMVSTGVDGTVCFWQWNT 167
           ***********9.*********666556666***************9764 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSVNSATLPN LVEINYATQL TGCTRSSSSL PVNMYQHIKM HRRILGHLSA VYCVAFDRTG 60
QRIFTGSDDC LVKIWSTHNG RLLATLRGHS AEISDMAVNY ENTMIAAGSC DKIIRVWCLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGTTA ACTCTGCTAC ATTACCAAAT CTGGGTAAGT GTACTTTAGA TTTCGCTATA 60
TACTCTATCC CTCTATTACA TATTGATACG AATGACACAA TATTAATATA TGCAGTAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004083	Anas platyrhynchos	60.70	0.00e+00	1962.00
IUUC-Cpo-021934	Cavia porcellus	72.19	0.00e+00	1964.00
IUUC-Csa-023352	Chlorocebus sabaeus	61.37	0.00e+00	2027.00
IUUC-Cho-024690	Choloepus hoffmanni	84.00	0.00e+00	671.00
IUUC-Fal-037307	Ficedula albicollis	68.84	0.00e+00	2159.00
IUUC-Gga-040865	Gallus gallus	76.87	0.00e+00	2088.00
IUUC-Ggo-045500	Gorilla gorilla	61.51	0.00e+00	2031.00
IUUC-Hsa-046350	Homo sapiens	61.49	0.00e+00	2035.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	68.73	0.00e+00	848.00
IUUC-Laf-053848	Loxodonta africana	72.23	0.00e+00	1932.00
IUUC-Mcc-054638	Macaca mulatta	61.33	0.00e+00	2033.00
IUUC-Meu-056739	Macropus eugenii	72.36	0.00e+00	893.00
IUUC-Mga-060165	Meleagris gallopavo	76.19	0.00e+00	2062.00
IUUC-Mmr-061227	Microcebus murinus	71.01	0.00e+00	1968.00
IUUC-Mdo-062074	Monodelphis domestica	72.00	0.00e+00	1931.00
IUUC-Mmu-064075	Mus musculus	59.86	0.00e+00	1977.00
IUUC-Nle-069402	Nomascus leucogenys	67.62	0.00e+00	2008.00
IUUC-Ont-072298	Oreochromis niloticus	61.20	0.00e+00	1648.00
IUUC-Oan-072954	Ornithorhynchus anatinus	62.57	0.00e+00	2039.00
IUUC-Ocu-074456	Oryctolagus cuniculus	61.38	0.00e+00	2051.00
IUUC-Ogl-077493	Oryza glaberrima	41.40	1.00e-28	122.00
IUUC-Olu-087745	Ostreococcus lucimarinus	27.50	7.00e-53	202.00
IUUC-Oga-087938	Otolemur garnettii	56.37	0.00e+00	1778.00
IUUC-Ptr-091213	Pan troglodytes	61.46	0.00e+00	2026.00
IUUC-Pan-092444	Papio anubis	61.12	0.00e+00	2021.00
IUUC-Psi-093271	Pelodiscus sinensis	73.68	0.00e+00	2164.00
IUUC-Pfo-097318	Poecilia formosa	61.67	0.00e+00	1586.00
IUUC-Pab-097573	Pongo abelii	71.33	0.00e+00	1913.00
IUUC-Rno-105687	Rattus norvegicus	68.51	0.00e+00	1885.00
IUUC-Sha-106680	Sarcophilus harrisii	61.45	0.00e+00	2005.00
IUUC-Sar-113519	Sorex araneus	61.67	0.00e+00	1349.00
IUUC-Tgu-116513	Taeniopygia guttata	76.52	0.00e+00	2085.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence