iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005059

Ensembl Protein ID

ENSACAP00000000312.2

UniProt Accession

G1K8F8; G1K8F8_ANOCA

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

DCUN1D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000000309.2	ENSACAT00000000323.2	ENSACAP00000000312.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.10e-85	286.4	61	246

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselk 89
           ++kkle+l++rYkdpq++ +igi+g+++fc+dl++dp++i+vLv+awk++aat+cefs++ef+dg+t+lgcd+++kl++ l++le+elk
   Q: 61   DRKKLEQLYNRYKDPQDEnKIGIDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSKKEFIDGMTELGCDTTDKLKALLPRLEQELK 149
           78**************999********************************************************************** PP
   S: 90   deqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWP 178
           d  kfkd+Y+f+fnfak++gqk+ldl++aia+w+L+l++r fk+ld+w+kfL e++k+si+kDtWnllL+f ++ia+d+snYdeegaWP
   Q: 150  DPMKFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLSGR-FKFLDLWNKFLLEHHKRSIPKDTWNLLLDFGNMIADDMSNYDEEGAWP 237
           ***************************************9.************************************************ PP
   S: 179  vliDefvey 187
           +l   ++ey
   Q: 238  YLHYLYIEY 246
           **9888888 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

KHKLKSSQKD KVRQFMAVTQ AGERTAIYCL MQNEWKLEVA TDNYFQNPDL YYKESMKISI 60
DRKKLEQLYN RYKDPQDENK IGIDGIQQFC DDLSLDPASI SVLVIAWKFR AATQCEFSKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGCATAAAC TTAAATCGTC TCAGAAGGAC AAGGTCCGCC AGTTTATGGC AGTTACTCAG 60
GCTGGTGAAA GGACTGCTAT ATACTGCTTA ATGCAAAATG AATGGAAACT AGAAGTGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR011992--EF-hand-dom_pair
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002697	Amborella trichopoda	42.73	1.00e-23	101.00
IUUC-Apl-003933	Anas platyrhynchos	91.54	2.00e-140	491.00
IUUC-Ame-011553	Astyanax mexicanus	84.71	7.00e-125	439.00
IUUC-Cja-018854	Callithrix jacchus	83.27	1.00e-128	451.00
IUUC-Cpo-021832	Cavia porcellus	83.78	1.00e-127	448.00
IUUC-Csa-023108	Chlorocebus sabaeus	83.66	5.00e-129	452.00
IUUC-Dre-028410	Danio rerio	90.31	1.00e-124	438.00
IUUC-Dno-029524	Dasypus novemcinctus	87.19	1.00e-125	441.00
IUUC-Dor-030143	Dipodomys ordii	83.20	2.00e-127	447.00
IUUC-Eca-033375	Equus caballus	87.55	1.00e-124	438.00
IUUC-Fal-036715	Ficedula albicollis	92.49	9.00e-139	485.00
IUUC-Gmo-038750	Gadus morhua	84.82	4.00e-131	459.00
IUUC-Gga-040224	Gallus gallus	91.44	4.00e-139	486.00
IUUC-Gac-041478	Gasterosteus aculeatus	85.60	4.00e-132	463.00
IUUC-Gma-043516	Glycine max	41.94	8.00e-57	213.00
IUUC-Ggo-044972	Gorilla gorilla	83.20	1.00e-127	448.00
IUUC-Hsa-046994	Homo sapiens	82.42	2.00e-127	447.00
IUUC-Itr-047902	Ictidomys tridecemlineatus	79.37	2.00e-122	431.00
IUUC-Lch-049751	Latimeria chalumnae	87.89	5.00e-135	473.00
IUUC-Loc-051976	Lepisosteus oculatus	86.72	6.00e-134	469.00
IUUC-Laf-053972	Loxodonta africana	87.55	1.00e-134	471.00
IUUC-Mcc-054700	Macaca mulatta	83.59	1.00e-128	451.00
IUUC-Meu-056791	Macropus eugenii	75.39	2.00e-107	381.00
IUUC-Mga-060072	Meleagris gallopavo	90.77	2.00e-139	487.00
IUUC-Mdo-062241	Monodelphis domestica	88.84	1.00e-127	448.00
IUUC-Mmu-063816	Mus musculus	83.59	8.00e-129	452.00
IUUC-Nle-069475	Nomascus leucogenys	84.13	1.00e-127	448.00
IUUC-Ont-071813	Oreochromis niloticus	86.38	5.00e-133	466.00
IUUC-Ola-086371	Oryzias latipes	85.60	1.00e-132	465.00
IUUC-Oga-088621	Otolemur garnettii	84.05	2.00e-129	454.00
IUUC-Ptr-091595	Pan troglodytes	82.81	5.00e-127	446.00
IUUC-Pan-092825	Papio anubis	83.59	1.00e-128	451.00
IUUC-Psi-093029	Pelodiscus sinensis	91.43	6.00e-131	459.00
IUUC-Pab-098197	Pongo abelii	82.23	1.00e-119	422.00
IUUC-Pca-100195	Procavia capensis	86.72	2.00e-131	460.00
IUUC-Pva-102691	Pteropus vampyrus	86.90	2.00e-131	461.00
IUUC-Rno-105016	Rattus norvegicus	82.42	2.00e-127	447.00
IUUC-Sha-106542	Sarcophilus harrisii	88.67	2.00e-135	474.00
IUUC-Tgu-117196	Taeniopygia guttata	92.46	4.00e-138	483.00
IUUC-Tru-118119	Takifugu rubripes	82.63	6.00e-131	459.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence