iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052531

Ensembl Protein ID

ENSLOCP00000020997.1

UniProt Accession

W5NK38; W5NK38_LEPOC

Genbank Protein ID

ENSLOCP00000020997

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AHAT01012025

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000016987.1	ENSLOCT00000021033.1	ENSLOCP00000020997.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.00e-15	55.1	88	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L+++kG++ +++  ++++++W+++ +  +g  G +P+n+v+ ++
   Q: 88   FVALYDYEARTEDDLNFRKGEKFQIL--NSTEGDWWEARSLSTGLTGYIPSNYVAPVD 143
           789***********************..8999**********************9987 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

RMGCVQCKDK GAAKLTDERD ASISQNAGYR YGADPTPQHY PNFGVTAIPN FNNFHAPGGQ 60
GMTVFGGVNS SSQTGTLRSR GGAGVTLFVA LYDYEARTED DLNFRKGEKF QILNSTEGDW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAATGGGCT GTGTGCAATG CAAGGATAAG GGAGCAGCAA AACTTACGGA CGAGCGGGAC 60
GCCAGTATAA GCCAGAACGC GGGTTATCGC TATGGGGCAG ATCCCACACC ACAGCACTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0060027--P:convergent extension involved in gastrulation
GO:0031101--P:fin regeneration
GO:0045859--P:regulation of protein kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002009	Ailuropoda melanoleuca	91.43	0.00e+00	1015.00
IUUC-Apl-003716	Anas platyrhynchos	85.90	0.00e+00	941.00
IUUC-Aca-005065	Anolis carolinensis	91.25	0.00e+00	1011.00
IUUC-Ame-011533	Astyanax mexicanus	95.82	0.00e+00	915.00
IUUC-Bta-012645	Bos taurus	91.25	0.00e+00	1014.00
IUUC-Cja-019027	Callithrix jacchus	91.43	0.00e+00	1015.00
IUUC-Cfa-021163	Canis familiaris	91.43	0.00e+00	1015.00
IUUC-Cpo-022315	Cavia porcellus	91.43	0.00e+00	1015.00
IUUC-Csa-023721	Chlorocebus sabaeus	91.43	0.00e+00	1016.00
IUUC-Cho-025014	Choloepus hoffmanni	91.43	0.00e+00	1016.00
IUUC-Dre-027985	Danio rerio	93.11	0.00e+00	1060.00
IUUC-Dno-030043	Dasypus novemcinctus	76.86	0.00e+00	897.00
IUUC-Dor-031035	Dipodomys ordii	90.13	0.00e+00	995.00
IUUC-Eca-033928	Equus caballus	81.91	0.00e+00	763.00
IUUC-Eeu-034582	Erinaceus europaeus	89.63	0.00e+00	633.00
IUUC-Fca-035582	Felis catus	91.43	0.00e+00	1015.00
IUUC-Fal-037320	Ficedula albicollis	86.22	0.00e+00	946.00
IUUC-Gmo-038992	Gadus morhua	92.76	0.00e+00	1045.00
IUUC-Gga-041262	Gallus gallus	86.22	0.00e+00	946.00
IUUC-Gac-042461	Gasterosteus aculeatus	91.81	0.00e+00	1047.00
IUUC-Ggo-044469	Gorilla gorilla	90.52	0.00e+00	1011.00
IUUC-Hsa-045723	Homo sapiens	91.43	0.00e+00	1016.00
IUUC-Itr-048519	Ictidomys tridecemlineatus	91.43	0.00e+00	1015.00
IUUC-Lch-049825	Latimeria chalumnae	90.88	0.00e+00	998.00
IUUC-Laf-053659	Loxodonta africana	91.43	0.00e+00	1014.00
IUUC-Mcc-055039	Macaca mulatta	85.61	0.00e+00	943.00
IUUC-Mga-060067	Meleagris gallopavo	91.64	0.00e+00	1014.00
IUUC-Mmr-061194	Microcebus murinus	91.43	0.00e+00	1015.00
IUUC-Mdo-062628	Monodelphis domestica	91.62	0.00e+00	1017.00
IUUC-Mmu-063896	Mus musculus	91.62	0.00e+00	1017.00
IUUC-Mpu-066333	Mustela putorius furo	91.25	0.00e+00	1014.00
IUUC-Mlu-067315	Myotis lucifugus	91.43	0.00e+00	1015.00
IUUC-Nle-068978	Nomascus leucogenys	86.03	0.00e+00	945.00
IUUC-Ont-071783	Oreochromis niloticus	93.67	0.00e+00	1031.00
IUUC-Oan-073714	Ornithorhynchus anatinus	93.63	0.00e+00	897.00
IUUC-Ocu-074284	Oryctolagus cuniculus	91.43	0.00e+00	1016.00
IUUC-Ola-087431	Oryzias latipes	92.18	0.00e+00	1049.00
IUUC-Oga-088789	Otolemur garnettii	85.85	0.00e+00	942.00
IUUC-Oar-089408	Ovis aries	91.25	0.00e+00	1014.00
IUUC-Ptr-091068	Pan troglodytes	91.43	0.00e+00	1016.00
IUUC-Pan-092217	Papio anubis	91.43	0.00e+00	1016.00
IUUC-Psi-093602	Pelodiscus sinensis	91.99	0.00e+00	1021.00
IUUC-Pfo-097519	Poecilia formosa	93.37	0.00e+00	1063.00
IUUC-Pab-097673	Pongo abelii	91.06	0.00e+00	1012.00
IUUC-Pca-100245	Procavia capensis	91.15	0.00e+00	917.00
IUUC-Pva-102645	Pteropus vampyrus	90.49	0.00e+00	984.00
IUUC-Rno-105372	Rattus norvegicus	91.62	0.00e+00	1017.00
IUUC-Sha-107637	Sarcophilus harrisii	91.25	0.00e+00	1005.00
IUUC-Sar-113016	Sorex araneus	80.82	0.00e+00	874.00
IUUC-Ssc-116389	Sus scrofa	91.06	0.00e+00	1011.00
IUUC-Tgu-117206	Taeniopygia guttata	86.22	0.00e+00	946.00
IUUC-Tru-118241	Takifugu rubripes	91.87	0.00e+00	1050.00
IUUC-Tni-120031	Tetraodon nigroviridis	92.36	0.00e+00	1048.00
IUUC-Tbe-127707	Tupaia belangeri	90.24	0.00e+00	916.00
IUUC-Ttr-129145	Tursiops truncatus	91.43	0.00e+00	1015.00
IUUC-Vpa-130815	Vicugna pacos	88.95	0.00e+00	961.00
IUUC-Xtr-132293	Xenopus tropicalis	84.92	0.00e+00	933.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence