iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045171

UUCD1 version

UUC-GoG-01091

Ensembl Protein ID

ENSGGOP00000006281.2

UniProt Accession

G3QU84; G3QU84_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000006417.2	ENSGGOT00000006449.2	ENSGGOP00000006281.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.00e-92	308.8	81	690

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+gNtC+mN+v+QcLsn+  l+e+l     ++ +        +e++++l+ l+++lw+++ +     e+++a++k+ ++f+g++q
   Q: 81   QGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPG------RAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQ 163
           6****************************9955555555......479***************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +Da Efl +lld+++e+l+ +++ p++e+   + +++s++  +++ +   ++s+++  Fq q++s+++c++c ++s++++pfl +slp+
   Q: 164  HDALEFLLWLLDRVHEDLEGSSRGPVSEKLPPEATKTSENclSPSAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPI 252
           ******************999999999998888888888777889999999************************************** PP
   S: 177  pgkeetkke................................................................................ 185
           p ++++ ++                                                                                
   Q: 253  PLRQTRFLSvtlvfpsksqrflrvglavpilstvaalrkmvaeeggvpadevilvelypsgfqrsffdeedlntiaegdnvyafqvpps 341
           ****98888******************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 342  psqgtlsahplglsasprlaaregqrfslslhseskvlilfcnlvgsgqqasrfgppfliredravswaqlqqsilskvrhlmkseapv 430
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 431  qnlgslfsirvvglsvacsylspkdsrplchwavdrvlhlrrpggpphvklavewdssvkerlfgslqeeraqdadsvwqqqqahqqhs 519
           ***************************************************************************************** PP
   S: 186  .slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekq 272
            +l++c++ +tkee+l ++++++c++c+ +q+   kl+l++lP++Li+hLkRf   + +++r+k+++ v+fpl+ L+++p++++++++ 
   Q: 520  cTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRF--CQVGERRNKLSTLVKFPLSgLNMAPHVAQRSTSP 606
           *****************************************************..88899************************77777 PP
   S: 273  ke....................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           +                     +  Y+L+av++H+G+l++GHY+ay++n  +g+W+ +dDs+V++++e+ev++   + aY+lfY++r
   Q: 607  EAglgpwpswkqpdclptsyplDFLYDLYAVCNHHGNLQGGHYTAYCRNsLDGQWYSYDDSTVEPLREDEVNT---RGAYILFYQKR 690
           66999999999999999**999***************************55788*******************...********985 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

RPRRSLRRLF SRFLLALGSR SRPGDSPPRP QPGHCDGDGE GGFACAPGPV PAAPGSPGEE 60
RPPGPQPQLP AGDGARPPGA QGLKNHGNTC FMNAVVQCLS NTDLLAEFLA LGRYRAAPGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGCCCCCG CCGCTCCCTG CGCCGCCTGT TCAGCCGCTT CCTGCTGGCG CTGGGCAGCC 60
GCTCACGCCC CGGGGACTCA CCGCCCCGGC CCCAGCCGGG ACACTGTGAT GGCGACGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	78.15	0.00e+00	1447.00
IUUC-Apl-003186	Anas platyrhynchos	50.68	2.00e-154	540.00
IUUC-Aca-004436	Anolis carolinensis	53.81	0.00e+00	802.00
IUUC-Ame-011153	Astyanax mexicanus	50.50	0.00e+00	887.00
IUUC-Bta-013560	Bos taurus	80.23	0.00e+00	1585.00
IUUC-Cja-018737	Callithrix jacchus	92.78	0.00e+00	1872.00
IUUC-Cfa-020347	Canis familiaris	77.29	0.00e+00	1469.00
IUUC-Csa-023656	Chlorocebus sabaeus	98.25	0.00e+00	1954.00
IUUC-Cho-024864	Choloepus hoffmanni	72.01	0.00e+00	914.00
IUUC-Csv-026086	Ciona savignyi	39.50	2.00e-119	423.00
IUUC-Dre-028066	Danio rerio	50.18	0.00e+00	914.00
IUUC-Dno-028855	Dasypus novemcinctus	73.01	0.00e+00	1368.00
IUUC-Dor-030475	Dipodomys ordii	88.30	0.00e+00	722.00
IUUC-Dme-032088	Drosophila melanogaster	36.54	1.00e-110	394.00
IUUC-Eca-034147	Equus caballus	85.90	0.00e+00	1480.00
IUUC-Eeu-034703	Erinaceus europaeus	62.02	0.00e+00	751.00
IUUC-Fca-036550	Felis catus	74.59	0.00e+00	1254.00
IUUC-Fal-036874	Ficedula albicollis	51.03	2.00e-155	543.00
IUUC-Gmo-039479	Gadus morhua	50.60	0.00e+00	645.00
IUUC-Gga-041092	Gallus gallus	52.10	0.00e+00	636.00
IUUC-Gac-042087	Gasterosteus aculeatus	51.74	0.00e+00	898.00
IUUC-Hsa-045961	Homo sapiens	99.81	0.00e+00	1988.00
IUUC-Itr-048673	Ictidomys tridecemlineatus	74.95	0.00e+00	679.00
IUUC-Lch-050332	Latimeria chalumnae	50.00	2.00e-175	610.00
IUUC-Loc-052852	Lepisosteus oculatus	62.81	0.00e+00	928.00
IUUC-Laf-054033	Loxodonta africana	78.80	0.00e+00	1555.00
IUUC-Mcc-055431	Macaca mulatta	97.57	0.00e+00	1959.00
IUUC-Mga-060115	Meleagris gallopavo	50.34	5.00e-154	538.00
IUUC-Mmr-061035	Microcebus murinus	86.99	0.00e+00	1680.00
IUUC-Mdo-062172	Monodelphis domestica	66.92	0.00e+00	971.00
IUUC-Mmu-063966	Mus musculus	80.42	0.00e+00	1572.00
IUUC-Mpu-066307	Mustela putorius furo	78.75	0.00e+00	1420.00
IUUC-Nle-070172	Nomascus leucogenys	98.45	0.00e+00	1966.00
IUUC-Opr-070499	Ochotona princeps	74.52	0.00e+00	1399.00
IUUC-Ont-071920	Oreochromis niloticus	52.56	0.00e+00	945.00
IUUC-Oan-073052	Ornithorhynchus anatinus	46.52	6.00e-168	584.00
IUUC-Ocu-074014	Oryctolagus cuniculus	83.69	0.00e+00	1214.00
IUUC-Ola-086360	Oryzias latipes	52.76	0.00e+00	944.00
IUUC-Oga-088202	Otolemur garnettii	84.53	0.00e+00	1700.00
IUUC-Oar-089819	Ovis aries	78.08	0.00e+00	1487.00
IUUC-Ptr-091076	Pan troglodytes	99.42	0.00e+00	1979.00
IUUC-Pan-092248	Papio anubis	97.86	0.00e+00	1941.00
IUUC-Pfo-096534	Poecilia formosa	60.15	0.00e+00	820.00
IUUC-Pab-098453	Pongo abelii	96.61	0.00e+00	1903.00
IUUC-Pca-100290	Procavia capensis	63.39	0.00e+00	726.00
IUUC-Pva-102317	Pteropus vampyrus	74.33	0.00e+00	1410.00
IUUC-Rno-104948	Rattus norvegicus	78.42	0.00e+00	1411.00
IUUC-Sha-106558	Sarcophilus harrisii	56.91	0.00e+00	1141.00
IUUC-Sar-113105	Sorex araneus	64.20	0.00e+00	1064.00
IUUC-Ssc-115312	Sus scrofa	80.27	0.00e+00	1564.00
IUUC-Tgu-116889	Taeniopygia guttata	50.68	4.00e-154	539.00
IUUC-Tru-117995	Takifugu rubripes	62.95	0.00e+00	906.00
IUUC-Tsy-119325	Tarsius syrichta	77.98	0.00e+00	771.00
IUUC-Tni-120517	Tetraodon nigroviridis	57.85	0.00e+00	858.00
IUUC-Tbe-127439	Tupaia belangeri	71.68	5.00e-143	501.00
IUUC-Ttr-128829	Tursiops truncatus	73.15	0.00e+00	1395.00
IUUC-Vpa-130306	Vicugna pacos	81.86	0.00e+00	635.00
IUUC-Xtr-132509	Xenopus tropicalis	52.33	0.00e+00	632.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence