iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074014

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02049485

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015475.3	ENSOCUT00000015477.3	ENSOCUP00000013297.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-72	243.7	10	555

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 71   rellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikcl 157
           +++ +a++k+ ++f+g++q+Da Efl +lld+++e+l  +++ p +++   + s+++++  +++     ++s+++  Fq q++s+++c+
   Q: 10   SSFQNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLGGSSRGPASQKLPPEASKAPENilSPSARLPPGQSFVQSHFQAQYRSSLTCP 98
           6799*********************************8877788877777777777777778888999999****************** PP
   S: 158  ecdnvssreepfldlslpvpgkeetkke............................................................. 185
           +c ++s++++pfl +slp+p ++++ ++                                                             
   Q: 99   HCLKQSNTFDPFLCVSLPIPLRQTRFLSvtlvflsksqrflrvglavpilstvaalrkmvaeeggipvdevilvelypsgfqrsffdee 187
           ***********************98888************************************************************* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 188  dlnsiaegdnvyafqaclapgqgtlavhppglsisprlaaregqrpglplhsenkvlilfcnlvgsgqqasrfgppfliredrsiswaq 276
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 277  lqqcilskvrclmrseapvqnlgslfsirvvglslacsylspqddrplsqwavdralhlrkpggpphvklavewdssakerlfgslqee 365
           ***************************************************************************************** PP
   S: 186  ....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkve 254
                               +l++c++ +tkee+l ++++++c++c+ +q+ + kl+l++lP++Li+hLkRf   + +++r+k+++ v+
   Q: 366  rvqdadsvrrqqqahqqhscTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGTVKLSLWTLPDILIIHLKRF--CQVGERRNKLSTLVK 452
           ************************************************************************..88899********** PP
   S: 255  fple.Ldlspfctspeekqke....................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeee 321
           fpl+ L+++p+++ + ++ ++                    +  Y+L+av++H+Gsl++GHY+ay++n  +g+W+ +dDs+V++++e+e
   Q: 453  FPLSgLNMAPHMAPRGSSATTgpgpwpswqqpaclpttyplDFLYDLYAVCNHHGSLQGGHYTAYCRNsLDGHWYSYDDSTVEPLQEDE 541
           **************777766699999999999999999999***************************44556**************** PP
   S: 322  vleetgstaYvlfYkrr 338
           + +   + aY+lfY++r
   Q: 542  IST---RGAYILFYQKR 555
           ***...********985 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

RQRAPRRPLS SFQNAVSKYG SQFQGNSQHD ALEFLLWLLD RVHEDLGGSS RGPASQKLPP 60
EASKAPENIL SPSARLPPGQ SFVQSHFQAQ YRSSLTCPHC LKQSNTFDPF LCVSLPIPLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACAGCGTG CGCCACGCCG ACCTCTGTCT TCCTTTCAGA ACGCTGTTTC CAAGTACGGC 60
TCTCAGTTCC AAGGGAATTC CCAGCACGAC GCCCTGGAGT TCCTGCTCTG GCTGCTGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	77.45	0.00e+00	1054.00
IUUC-Apl-003186	Anas platyrhynchos	49.66	9.00e-151	528.00
IUUC-Aca-004436	Anolis carolinensis	64.38	0.00e+00	739.00
IUUC-Ame-011153	Astyanax mexicanus	57.68	0.00e+00	739.00
IUUC-Bta-013560	Bos taurus	80.00	0.00e+00	1159.00
IUUC-Cja-018737	Callithrix jacchus	81.91	0.00e+00	1199.00
IUUC-Cfa-020347	Canis familiaris	77.09	0.00e+00	1061.00
IUUC-Csa-023656	Chlorocebus sabaeus	83.29	0.00e+00	1214.00
IUUC-Cho-024864	Choloepus hoffmanni	66.83	0.00e+00	734.00
IUUC-Csv-026086	Ciona savignyi	38.25	9.00e-104	370.00
IUUC-Dre-028066	Danio rerio	55.91	0.00e+00	725.00
IUUC-Dno-028855	Dasypus novemcinctus	75.00	0.00e+00	1046.00
IUUC-Dor-030475	Dipodomys ordii	72.27	0.00e+00	829.00
IUUC-Dme-032088	Drosophila melanogaster	35.99	4.00e-88	320.00
IUUC-Ete-032975	Echinops telfairi	41.27	9.00e-96	345.00
IUUC-Eca-034147	Equus caballus	81.56	0.00e+00	1167.00
IUUC-Eeu-034703	Erinaceus europaeus	71.01	6.00e-137	481.00
IUUC-Fca-036550	Felis catus	75.25	0.00e+00	988.00
IUUC-Fal-036874	Ficedula albicollis	50.43	1.00e-150	527.00
IUUC-Gmo-038903	Gadus morhua	49.93	1.00e-159	556.00
IUUC-Gga-041092	Gallus gallus	49.42	5.00e-150	525.00
IUUC-Gac-042087	Gasterosteus aculeatus	58.35	0.00e+00	721.00
IUUC-Ggo-045171	Gorilla gorilla	83.69	0.00e+00	1216.00
IUUC-Hsa-045961	Homo sapiens	83.82	0.00e+00	1218.00
IUUC-Itr-048158	Ictidomys tridecemlineatus	51.19	2.00e-150	526.00
IUUC-Lch-050332	Latimeria chalumnae	47.73	3.00e-142	499.00
IUUC-Loc-052852	Lepisosteus oculatus	62.36	0.00e+00	793.00
IUUC-Laf-054033	Loxodonta africana	78.65	0.00e+00	1056.00
IUUC-Mcc-055431	Macaca mulatta	82.89	0.00e+00	1207.00
IUUC-Meu-056822	Macropus eugenii	41.46	2.00e-105	377.00
IUUC-Mga-060115	Meleagris gallopavo	49.25	2.00e-149	523.00
IUUC-Mmr-061035	Microcebus murinus	83.55	0.00e+00	1150.00
IUUC-Mdo-062172	Monodelphis domestica	65.49	0.00e+00	821.00
IUUC-Mmu-063966	Mus musculus	82.53	0.00e+00	1155.00
IUUC-Mpu-066307	Mustela putorius furo	80.17	0.00e+00	1061.00
IUUC-Mlu-067870	Myotis lucifugus	50.34	2.00e-148	520.00
IUUC-Nle-070172	Nomascus leucogenys	83.82	0.00e+00	1214.00
IUUC-Opr-070499	Ochotona princeps	78.24	0.00e+00	1105.00
IUUC-Ont-071920	Oreochromis niloticus	60.39	0.00e+00	767.00
IUUC-Oan-073175	Ornithorhynchus anatinus	50.17	6.00e-149	521.00
IUUC-Ola-086360	Oryzias latipes	58.23	0.00e+00	760.00
IUUC-Oga-088202	Otolemur garnettii	79.60	0.00e+00	1105.00
IUUC-Oar-089819	Ovis aries	79.60	0.00e+00	1152.00
IUUC-Ptr-091076	Pan troglodytes	83.82	0.00e+00	1219.00
IUUC-Pan-092248	Papio anubis	82.89	0.00e+00	1207.00
IUUC-Psi-093881	Pelodiscus sinensis	48.98	8.00e-148	518.00
IUUC-Pfo-096332	Poecilia formosa	56.39	0.00e+00	707.00
IUUC-Pab-098453	Pongo abelii	84.31	0.00e+00	1219.00
IUUC-Pca-100290	Procavia capensis	63.49	4.00e-154	538.00
IUUC-Pva-102317	Pteropus vampyrus	71.05	0.00e+00	961.00
IUUC-Rno-104948	Rattus norvegicus	81.79	0.00e+00	1145.00
IUUC-Sha-106558	Sarcophilus harrisii	64.76	0.00e+00	888.00
IUUC-Sar-113105	Sorex araneus	67.22	0.00e+00	906.00
IUUC-Ssc-115312	Sus scrofa	81.14	0.00e+00	1169.00
IUUC-Tgu-116889	Taeniopygia guttata	50.08	1.00e-149	523.00
IUUC-Tru-117995	Takifugu rubripes	60.76	0.00e+00	767.00
IUUC-Tsy-119325	Tarsius syrichta	74.01	0.00e+00	722.00
IUUC-Tni-120517	Tetraodon nigroviridis	56.65	0.00e+00	714.00
IUUC-Tbe-127439	Tupaia belangeri	73.03	7.00e-78	285.00
IUUC-Ttr-128829	Tursiops truncatus	71.08	0.00e+00	974.00
IUUC-Vpa-130306	Vicugna pacos	74.61	2.00e-129	456.00
IUUC-Xtr-132509	Xenopus tropicalis	49.49	6.00e-148	518.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence