iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089710

Ensembl Protein ID

ENSOARP00000005875.1

UniProt Accession

W5P621; W5P621_SHEEP

Genbank Protein ID

ENSOARP00000005875

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01068290

Gene Name

USP7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000005469.1	ENSOART00000005965.1	ENSOARP00000005875.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-68	231.8	222	528

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+g+tCYmNS+LQ+L+++++lr+++    + +      +++++++  +lq++f el ++++k v +++l+k++++e   +++++q
   Q: 222  VGLKNQGATCYMNSLLQTLFFTNQLRKAVYM-MPTEG-----DDSSKSVPLALQRVFYEL-QHSDKPVGTKKLTKSFGWET--LDSFMQ 301
           6******************************.44433.....466889************.88889************887..67**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++lld++e+++                          k +  + +i +lF+g++ s i+c+e d +s r+e+ +d++l+++g
   Q: 302  HDVQELCRVLLDNVENKM--------------------------KGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKG 364
           ******************..........................789****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           k+     ++ +++ ++++ e+l+g+nky   +  ++qeaek +k+ +lP+vL+l+L+Rf ++ ++++++kin+++efp++L l++f+++
   Q: 365  KK-----NIFESFVDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQK 447
           **.....9*********************9996.7****************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg............staYvlfYkr 337
           ++ k+  + +Y L+av+vHsG  ++GHYv+y +   +gkW++fdD+ V+ +++ee  e +             ++aY+l+Y r
   Q: 448  TDPKD--PANYILHAVLVHSGDNHGGHYVVYLNPkGDGKWCKFDDDVVSRCTKEEAIEHNYgghdddlsvrhcTNAYMLVYIR 528
           88777..*************************9834566************86666664446*******************87 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

CSHSDVAERT LPSPPPILLQ SHADMAGNCA LGPQAGDTDD PPRITQNPVI NGNVAMSDGH 60
SNTEEDMEDD TSWRSEATFQ FTVERFSRLS ESVLSPPCFV RNLPWKIMVM PRFYPDRPHQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCAGTCACT CTGATGTGGC TGAGAGAACC CTGCCCTCCC CTCCCCCCAC CCCTAGCAGA 60
TTCTGCTGCA GAGCCATGCA GACATGGCGG GGAACTGCGC ACTTGGACCA CAAGGTGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0010216--P:maintenance of DNA methylation
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0050821--P:protein stabilization
GO:0006283--P:transcription-coupled nucleotide-excision repair
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	33.30	1.00e-143	504.00
IUUC-Aml-002408	Ailuropoda melanoleuca	98.02	0.00e+00	2245.00
IUUC-Atr-003067	Amborella trichopoda	37.06	5.00e-124	439.00
IUUC-Apl-003558	Anas platyrhynchos	96.85	0.00e+00	2196.00
IUUC-Aca-004518	Anolis carolinensis	90.59	0.00e+00	2058.00
IUUC-Aly-006453	Arabidopsis lyrata	37.10	2.00e-161	563.00
IUUC-Ath-007610	Arabidopsis thaliana	35.81	1.00e-157	550.00
IUUC-Ago-007849	Ashbya gossypii	32.69	7.00e-139	488.00
IUUC-Acl-008327	Aspergillus clavatus	34.01	2.00e-170	593.00
IUUC-Afl-008491	Aspergillus flavus	34.75	5.00e-165	575.00
IUUC-Afu-008804	Aspergillus fumigatus	35.04	6.00e-162	565.00
IUUC-Ang-009776	Aspergillus niger	34.64	7.00e-162	565.00
IUUC-Aor-009998	Aspergillus oryzae	34.01	1.00e-156	547.00
IUUC-Ate-010428	Aspergillus terreus	34.60	4.00e-164	572.00
IUUC-Ame-010903	Astyanax mexicanus	93.36	0.00e+00	2127.00
IUUC-Bgr-012132	Blumeria graminis	31.71	1.00e-143	504.00
IUUC-Bta-013192	Bos taurus	99.91	0.00e+00	2221.00
IUUC-Bci-013924	Botrytis cinerea	34.04	2.00e-150	526.00
IUUC-Bdi-014920	Brachypodium distachyon	35.82	1.00e-157	551.00
IUUC-Bol-015224	Brassica oleracea	36.86	2.00e-158	553.00
IUUC-Bra-017448	Brassica rapa	36.64	1.00e-157	550.00
IUUC-Cel-018219	Caenorhabditis elegans	33.95	2.00e-155	543.00
IUUC-Cja-019006	Callithrix jacchus	97.03	0.00e+00	2221.00
IUUC-Cfa-020361	Canis familiaris	99.08	0.00e+00	2225.00
IUUC-Cpo-022320	Cavia porcellus	99.16	0.00e+00	2207.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	43.84	2.00e-91	329.00
IUUC-Csa-024050	Chlorocebus sabaeus	99.16	0.00e+00	2211.00
IUUC-Cho-024434	Choloepus hoffmanni	90.04	0.00e+00	1429.00
IUUC-Cin-025689	Ciona intestinalis	54.59	0.00e+00	1216.00
IUUC-Csv-025963	Ciona savignyi	52.41	0.00e+00	1166.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	33.33	7.00e-151	528.00
IUUC-Cne-026968	Cryptococcus neoformans	36.48	0.00e+00	628.00
IUUC-Cme-027103	Cyanidioschyzon merolae	35.69	2.00e-115	410.00
IUUC-Dre-028510	Danio rerio	93.54	0.00e+00	2128.00
IUUC-Dno-029696	Dasypus novemcinctus	97.91	0.00e+00	2223.00
IUUC-Dor-030611	Dipodomys ordii	82.29	0.00e+00	984.00
IUUC-Dse-031433	Dothistroma septosporum	34.09	5.00e-147	515.00
IUUC-Dme-031583	Drosophila melanogaster	48.77	0.00e+00	1046.00
IUUC-Ete-033191	Echinops telfairi	96.31	0.00e+00	2201.00
IUUC-Eca-034122	Equus caballus	98.71	0.00e+00	2221.00
IUUC-Eeu-035292	Erinaceus europaeus	76.05	0.00e+00	682.00
IUUC-Fca-036377	Felis catus	98.54	0.00e+00	2231.00
IUUC-Fal-036964	Ficedula albicollis	96.97	0.00e+00	2156.00
IUUC-Fox-037695	Fusarium oxysporum	33.39	1.00e-158	554.00
IUUC-Fso-038084	Fusarium solani	33.55	2.00e-158	553.00
IUUC-Gmo-038644	Gadus morhua	93.13	0.00e+00	2124.00
IUUC-Ggr-040029	Gaeumannomyces graminis	33.67	5.00e-157	548.00
IUUC-Gga-040944	Gallus gallus	97.10	0.00e+00	2188.00
IUUC-Gac-041740	Gasterosteus aculeatus	93.87	0.00e+00	2134.00
IUUC-Gma-043300	Glycine max	36.48	7.00e-169	588.00
IUUC-Ggo-044947	Gorilla gorilla	98.11	0.00e+00	2250.00
IUUC-Hsa-046278	Homo sapiens	98.98	0.00e+00	2207.00
IUUC-Hvu-047749	Hordeum vulgare	37.01	8.00e-143	501.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	98.93	0.00e+00	1898.00
IUUC-Kpa-049121	Komagataella pastoris	31.12	1.00e-126	448.00
IUUC-Lch-049847	Latimeria chalumnae	96.29	0.00e+00	2177.00
IUUC-Lpe-051505	Leersia perrieri	36.06	6.00e-144	505.00
IUUC-Loc-052234	Lepisosteus oculatus	93.73	0.00e+00	1419.00
IUUC-Lma-053169	Leptosphaeria maculans	36.67	1.00e-167	583.00
IUUC-Laf-053566	Loxodonta africana	99.16	0.00e+00	2209.00
IUUC-Mcc-055549	Macaca mulatta	99.16	0.00e+00	2204.00
IUUC-Meu-056887	Macropus eugenii	87.97	0.00e+00	1276.00
IUUC-Mor-057149	Magnaporthe oryzae	34.51	1.00e-158	553.00
IUUC-Mpo-057536	Magnaporthe poae	33.61	9.00e-158	551.00
IUUC-Mtr-058583	Medicago truncatula	37.56	3.00e-165	575.00
IUUC-Mla-058899	Melampsora laricipopulina	36.98	1.00e-171	597.00
IUUC-Mga-060148	Meleagris gallopavo	96.50	0.00e+00	2205.00
IUUC-Mvi-060207	Microbotryum violaceum	37.52	0.00e+00	634.00
IUUC-Mmr-060946	Microcebus murinus	98.98	0.00e+00	2207.00
IUUC-Mdo-062079	Monodelphis domestica	90.47	0.00e+00	1972.00
IUUC-Mmu-063678	Mus musculus	98.98	0.00e+00	2202.00
IUUC-Mac-065416	Musa acuminata	36.73	2.00e-158	553.00
IUUC-Mpu-066744	Mustela putorius furo	99.24	0.00e+00	2165.00
IUUC-Mlu-067949	Myotis lucifugus	97.84	0.00e+00	2231.00
IUUC-Nfi-068342	Neosartorya fischeri	35.38	9.00e-162	564.00
IUUC-Ncr-068818	Neurospora crassa	33.67	4.00e-163	569.00
IUUC-Nle-070064	Nomascus leucogenys	99.07	0.00e+00	2210.00
IUUC-Opr-071001	Ochotona princeps	95.88	0.00e+00	1834.00
IUUC-Ont-072095	Oreochromis niloticus	93.27	0.00e+00	2127.00
IUUC-Oan-073483	Ornithorhynchus anatinus	97.63	0.00e+00	2136.00
IUUC-Ocu-073967	Oryctolagus cuniculus	97.31	0.00e+00	2149.00
IUUC-Oba-075811	Oryza barthii	34.23	1.00e-141	497.00
IUUC-Obr-076514	Oryza brachyantha	36.68	2.00e-156	546.00
IUUC-Ogl-077038	Oryza glaberrima	35.79	3.00e-151	529.00
IUUC-Ogu-078265	Oryza glumaepatula	34.19	4.00e-137	482.00
IUUC-Oin-079513	Oryza indica	35.33	6.00e-143	501.00
IUUC-Olo-081067	Oryza longistaminata	34.18	6.00e-140	491.00
IUUC-Ome-081879	Oryza meridionalis	36.37	2.00e-152	533.00
IUUC-Oni-082409	Oryza nivara	33.55	2.00e-141	496.00
IUUC-Opu-083199	Oryza punctata	35.73	4.00e-148	519.00
IUUC-Oru-085109	Oryza rufipogon	35.76	2.00e-147	516.00
IUUC-Osa-085418	Oryza sativa	38.82	2.00e-131	463.00
IUUC-Ola-086640	Oryzias latipes	93.59	0.00e+00	2122.00
IUUC-Olu-087874	Ostreococcus lucimarinus	33.73	6.00e-144	505.00
IUUC-Oga-089059	Otolemur garnettii	91.52	0.00e+00	2061.00
IUUC-Ptr-091334	Pan troglodytes	98.11	0.00e+00	2250.00
IUUC-Pan-091717	Papio anubis	99.43	0.00e+00	2145.00
IUUC-Psi-093933	Pelodiscus sinensis	96.49	0.00e+00	2194.00
IUUC-Pma-094648	Petromyzon marinus	82.16	0.00e+00	1720.00
IUUC-Pno-095020	Phaeosphaeria nodorum	35.16	1.00e-149	524.00
IUUC-Ppa-096020	Physcomitrella patens	34.71	1.00e-162	566.00
IUUC-Pfo-096181	Poecilia formosa	93.17	0.00e+00	2125.00
IUUC-Pab-098231	Pongo abelii	95.59	0.00e+00	2177.00
IUUC-Pop-099680	Populus trichocarpa	36.58	2.00e-162	566.00
IUUC-Pca-100543	Procavia capensis	80.46	0.00e+00	1035.00
IUUC-Ppe-101523	Prunus persica	36.07	6.00e-156	545.00
IUUC-Pva-102472	Pteropus vampyrus	97.30	0.00e+00	2207.00
IUUC-Pgr-103463	Puccinia graminis	36.89	6.00e-171	595.00
IUUC-Ptt-103716	Puccinia triticina	37.85	7.00e-168	584.00
IUUC-Pte-104360	Pyrenophora teres	36.13	6.00e-151	528.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	35.75	3.00e-149	522.00
IUUC-Rno-105816	Rattus norvegicus	99.16	0.00e+00	2209.00
IUUC-Sce-106230	Saccharomyces cerevisiae	29.93	1.00e-122	434.00
IUUC-Sha-107439	Sarcophilus harrisii	97.95	0.00e+00	2183.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	32.94	7.00e-140	491.00
IUUC-Spo-108019	Schizosaccharomyces pombe	34.54	2.00e-144	507.00
IUUC-Smo-109308	Selaginella moellendorffii	35.57	8.00e-154	538.00
IUUC-Sit-110367	Setaria italica	36.25	2.00e-158	553.00
IUUC-Sly-111774	Solanum lycopersicum	36.30	1.00e-167	584.00
IUUC-Stu-112387	Solanum tuberosum	36.18	1.00e-166	580.00
IUUC-Sar-113685	Sorex araneus	96.67	0.00e+00	2203.00
IUUC-Sbi-114037	Sorghum bicolor	36.96	1.00e-159	557.00
IUUC-Sre-115156	Sporisorium reilianum	36.91	0.00e+00	630.00
IUUC-Ssc-116297	Sus scrofa	99.16	0.00e+00	2211.00
IUUC-Tgu-116767	Taeniopygia guttata	96.76	0.00e+00	2196.00
IUUC-Tru-118208	Takifugu rubripes	93.41	0.00e+00	2099.00
IUUC-Tsy-119277	Tarsius syrichta	86.54	0.00e+00	730.00
IUUC-Tni-119890	Tetraodon nigroviridis	93.41	0.00e+00	2100.00
IUUC-Tca-121696	Theobroma cacao	36.73	2.00e-157	550.00
IUUC-Tre-122169	Trichoderma reesei	33.33	5.00e-153	535.00
IUUC-Tvi-122600	Trichoderma virens	34.34	7.00e-161	561.00
IUUC-Tae-123032	Triticum aestivum	35.50	2.00e-157	550.00
IUUC-Tur-126287	Triticum urartu	35.22	4.00e-150	525.00
IUUC-Tme-127045	Tuber melanosporum	35.44	5.00e-167	582.00
IUUC-Tbe-127696	Tupaia belangeri	88.27	4.00e-160	558.00
IUUC-Ttr-129161	Tursiops truncatus	98.65	0.00e+00	2257.00
IUUC-Uma-129535	Ustilago maydis	37.19	0.00e+00	640.00
IUUC-Vda-129708	Verticillium dahliae	32.90	1.00e-158	553.00
IUUC-Vvi-130882	Vitis vinifera	36.33	3.00e-157	549.00
IUUC-Xtr-132073	Xenopus tropicalis	92.87	0.00e+00	2081.00
IUUC-Xma-133949	Xiphophorus maculatus	92.90	0.00e+00	2116.00
IUUC-Yli-134527	Yarrowia lipolytica	32.72	1.00e-138	487.00
IUUC-Zma-135550	Zea mays	35.16	8.00e-149	521.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence