iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pma-094232

Ensembl Protein ID

ENSPMAP00000010603.1

UniProt Accession

S4RZG2; S4RZG2_PETMA

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000009640.1	ENSPMAT00000010649.1	ENSPMAP00000010603.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-13	49.7	18	81

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlvi......ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydy+a ++d+L+++kG++ ++i           +++W+++ +  +g +G +P+n+v+ ++
   Q: 18   FVALYDYDARTQDDLSFRKGEKFQIInntievAVVYREGDWWEARSLSTGNKGYIPSNYVAPAD 81
           789***********************644433334679**********************9875 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MSVSSPQRTH LTGGVTLFVA LYDYDARTQD DLSFRKGEKF QIINNTIEVA VVYREGDWWE 60
ARSLSTGNKG YIPSNYVAPA DSVQAEEWYF GKVSRKDAER QLLCPGNPRG TFLIRESETT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGGCGGTG AGAGCGGCGC CGCCCGTCTT TCTCGTCTCT CGCCTGCTCC TCTCGCTTCC 60
TCCTCCTCAC TTCCTCCCCG TGTTCCACGC TTCGCCTCCT CGTTCGGCGT GTTTTGTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000172	Aegilops tauschii	29.48	6.00e-21	94.70
IUUC-Aml-002374	Ailuropoda melanoleuca	87.72	0.00e+00	860.00
IUUC-Atr-002778	Amborella trichopoda	30.22	3.00e-24	105.00
IUUC-Apl-004032	Anas platyrhynchos	86.44	0.00e+00	864.00
IUUC-Aca-004255	Anolis carolinensis	85.81	0.00e+00	862.00
IUUC-Aly-005712	Arabidopsis lyrata	30.90	2.00e-19	89.70
IUUC-Ath-007146	Arabidopsis thaliana	31.75	1.00e-23	103.00
IUUC-Ame-010954	Astyanax mexicanus	85.41	0.00e+00	859.00
IUUC-Bta-013503	Bos taurus	87.90	0.00e+00	861.00
IUUC-Bdi-014324	Brachypodium distachyon	35.96	7.00e-24	104.00
IUUC-Bol-016049	Brassica oleracea	32.37	4.00e-18	85.10
IUUC-Bra-017486	Brassica rapa	32.12	8.00e-22	97.40
IUUC-Cja-019694	Callithrix jacchus	87.69	0.00e+00	863.00
IUUC-Cfa-020402	Canis familiaris	87.90	0.00e+00	865.00
IUUC-Cpo-022506	Cavia porcellus	87.69	0.00e+00	862.00
IUUC-Csa-023713	Chlorocebus sabaeus	87.90	0.00e+00	862.00
IUUC-Cho-025014	Choloepus hoffmanni	82.57	0.00e+00	792.00
IUUC-Cin-025390	Ciona intestinalis	71.79	0.00e+00	676.00
IUUC-Csv-026029	Ciona savignyi	71.95	0.00e+00	639.00
IUUC-Dre-027978	Danio rerio	87.44	0.00e+00	845.00
IUUC-Dno-029651	Dasypus novemcinctus	78.84	0.00e+00	816.00
IUUC-Dor-030202	Dipodomys ordii	87.17	0.00e+00	851.00
IUUC-Ete-033170	Echinops telfairi	79.78	0.00e+00	789.00
IUUC-Eca-034157	Equus caballus	87.47	0.00e+00	859.00
IUUC-Eeu-034950	Erinaceus europaeus	85.14	3.00e-142	496.00
IUUC-Fca-036233	Felis catus	86.84	0.00e+00	866.00
IUUC-Fal-037461	Ficedula albicollis	86.23	0.00e+00	863.00
IUUC-Gmo-038929	Gadus morhua	86.78	0.00e+00	832.00
IUUC-Gga-041107	Gallus gallus	86.23	0.00e+00	863.00
IUUC-Gac-042321	Gasterosteus aculeatus	86.83	0.00e+00	851.00
IUUC-Ggo-044469	Gorilla gorilla	82.57	0.00e+00	793.00
IUUC-Hsa-047010	Homo sapiens	87.69	0.00e+00	862.00
IUUC-Hvu-047855	Hordeum vulgare	28.79	2.00e-21	96.30
IUUC-Itr-049014	Ictidomys tridecemlineatus	80.97	0.00e+00	828.00
IUUC-Lch-050239	Latimeria chalumnae	86.41	0.00e+00	863.00
IUUC-Lpe-051166	Leersia perrieri	35.47	7.00e-25	107.00
IUUC-Loc-052314	Lepisosteus oculatus	84.99	0.00e+00	817.00
IUUC-Laf-053517	Loxodonta africana	87.69	0.00e+00	863.00
IUUC-Mcc-055626	Macaca mulatta	87.90	0.00e+00	863.00
IUUC-Meu-056155	Macropus eugenii	76.69	0.00e+00	735.00
IUUC-Mga-059310	Meleagris gallopavo	86.23	0.00e+00	863.00
IUUC-Mmr-061652	Microcebus murinus	87.74	0.00e+00	866.00
IUUC-Mdo-062963	Monodelphis domestica	86.67	0.00e+00	856.00
IUUC-Mmu-064128	Mus musculus	87.74	0.00e+00	863.00
IUUC-Mpu-065906	Mustela putorius furo	87.90	0.00e+00	865.00
IUUC-Mlu-067035	Myotis lucifugus	86.91	0.00e+00	855.00
IUUC-Nle-068978	Nomascus leucogenys	84.87	0.00e+00	816.00
IUUC-Opr-070299	Ochotona princeps	79.05	0.00e+00	766.00
IUUC-Ont-072337	Oreochromis niloticus	85.41	0.00e+00	865.00
IUUC-Oan-072997	Ornithorhynchus anatinus	87.04	0.00e+00	857.00
IUUC-Ocu-074171	Oryctolagus cuniculus	87.74	0.00e+00	865.00
IUUC-Oba-075994	Oryza barthii	34.98	2.00e-22	99.80
IUUC-Ogl-077331	Oryza glaberrima	35.47	4.00e-25	108.00
IUUC-Ogu-078962	Oryza glumaepatula	34.25	4.00e-25	108.00
IUUC-Oin-079172	Oryza indica	35.47	4.00e-25	108.00
IUUC-Olo-080286	Oryza longistaminata	35.47	4.00e-25	108.00
IUUC-Ome-081400	Oryza meridionalis	35.47	3.00e-25	108.00
IUUC-Oni-082734	Oryza nivara	35.47	1.00e-24	107.00
IUUC-Oru-084741	Oryza rufipogon	35.47	3.00e-25	108.00
IUUC-Osa-085779	Oryza sativa	35.47	3.00e-25	108.00
IUUC-Ola-086619	Oryzias latipes	83.82	0.00e+00	846.00
IUUC-Oga-087957	Otolemur garnettii	87.47	0.00e+00	862.00
IUUC-Oar-089670	Ovis aries	87.90	0.00e+00	861.00
IUUC-Ptr-091352	Pan troglodytes	87.69	0.00e+00	862.00
IUUC-Pan-092202	Papio anubis	87.90	0.00e+00	863.00
IUUC-Psi-093310	Pelodiscus sinensis	86.65	0.00e+00	868.00
IUUC-Pfo-096137	Poecilia formosa	84.03	0.00e+00	850.00
IUUC-Pab-098301	Pongo abelii	87.90	0.00e+00	860.00
IUUC-Pca-100245	Procavia capensis	82.68	0.00e+00	798.00
IUUC-Ppe-102072	Prunus persica	33.69	8.00e-28	117.00
IUUC-Pva-102592	Pteropus vampyrus	83.80	0.00e+00	816.00
IUUC-Rno-105544	Rattus norvegicus	87.53	0.00e+00	860.00
IUUC-Sha-107539	Sarcophilus harrisii	79.92	0.00e+00	818.00
IUUC-Sit-110444	Setaria italica	33.80	1.00e-19	90.10
IUUC-Sar-113364	Sorex araneus	84.30	0.00e+00	822.00
IUUC-Sbi-114480	Sorghum bicolor	34.21	1.00e-24	107.00
IUUC-Ssc-115762	Sus scrofa	81.18	0.00e+00	829.00
IUUC-Tgu-117380	Taeniopygia guttata	86.23	0.00e+00	863.00
IUUC-Tru-117784	Takifugu rubripes	86.11	0.00e+00	859.00
IUUC-Tni-120433	Tetraodon nigroviridis	84.32	0.00e+00	833.00
IUUC-Tae-123018	Triticum aestivum	30.28	7.00e-22	97.40
IUUC-Tur-126022	Triticum urartu	29.53	1.00e-21	97.10
IUUC-Tbe-127707	Tupaia belangeri	82.17	0.00e+00	784.00
IUUC-Ttr-128893	Tursiops truncatus	87.69	0.00e+00	860.00
IUUC-Vpa-130060	Vicugna pacos	87.74	0.00e+00	863.00
IUUC-Vvi-131181	Vitis vinifera	30.77	2.00e-22	99.80
IUUC-Xtr-132322	Xenopus tropicalis	86.75	0.00e+00	859.00
IUUC-Xma-134012	Xiphophorus maculatus	84.45	0.00e+00	855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence