iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005061

UUCD1 version

UUC-AnC-01004

Ensembl Protein ID

ENSACAP00000004927.3

UniProt Accession

H9G9T9; H9G9T9_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP47

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004976.3	ENSACAT00000005040.3	ENSACAP00000004927.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-75	254.8	188	562

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+  tCY+NS+LQ+L+++pe+r++l +    +++e++ ++p +++  +lq+lf  l++skk+a++++++++++++ ++e    +q
   Q: 188  VGLVNQAMTCYLNSLLQTLFMTPEFRNALYK---WEFEESE-EDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSE--AWQQ 270
           6******************************...5555443.5899*********************************9998..9*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++++d+le++                           k++++ +li++l+qg+lk+ ++clec+ +s r ++ ld++l ++ 
   Q: 271  HDVQELCRVMFDALEQKW--------------------------KQTEQADLINQLYQGKLKDYVRCLECGYESWRIDTYLDIPLVIRP 333
           ******************..........................678999*************************************95 PP
   S: 179  ke.etkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
              +++  s++++L++f ++e l+g n+y+ce+ckkk++a+k l++ ++P  L+l+LkRf f+ ++++r+k+n++++fp+eLd+ +f  
   Q: 334  YGsSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMGSFID 422
           54045678******************************************************************************999 PP
   S: 267  speekqke.....................................................kkkYeLiavvvHsGslssGHYvayvkn. 301
            ++ek+ +                                                     +  YeL++v+vHsGs+ +GHY+a++k+ 
   Q: 423  IEDEKSPQtesctdsgaenegschsdqmsndfsnddgvdegiclesnstveriskvaneknSLLYELFSVMVHSGSAAGGHYYACIKSf 511
           86655555677777777777777777778888888888888888888888888888888889**************************5 PP
   S: 302  ekgkWllfdDskVtevkeeevleetg................staYvlfYk 336
           ++++W+ f+D++V++++ e+++++ g                ++aY+l+Y+
   Q: 512  SDDQWYSFNDQHVSKITHEDIKKTYGgtsgsrgyyssafassTNAYMLIYR 562
           5666*******************888************************8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MVPSEENQLV PKEDMLWRCR QSIFDEMKKK FSQNESAADE PRVLCIIQDT TNSKTVNERI 60
TLNLPASTPV KRLFEDVATK VGYVNGTFDL IWGNGVNVAN TTPLDQSSDK SVVNAGFESG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTACTTAT TTTTTCTTTA TTCACCCCCC CCCCCCTTTC CTCAAGCTTC TGGCACTTTG 60
TCAGAACAAA AAGAATAGAA AGACCAGTAC CTGGATGGGA AACTTCCAGA AACTCTTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF14560--Ubiquitin_2
PF00443--UCH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006284--P:base-excision repair
GO:0034644--P:cellular response to UV
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010972--P:negative regulation of G2/M transition of mitotic cell cycle
GO:1902230--P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0030307--P:positive regulation of cell growth
GO:0042981--P:regulation of apoptotic process
GO:0042493--P:response to drug
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

acs:100564462

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002228	Ailuropoda melanoleuca	86.11	0.00e+00	2291.00
IUUC-Apl-003486	Anas platyrhynchos	89.88	0.00e+00	2347.00
IUUC-Ame-011206	Astyanax mexicanus	80.81	0.00e+00	2108.00
IUUC-Bta-012942	Bos taurus	86.88	0.00e+00	2309.00
IUUC-Cel-018600	Caenorhabditis elegans	39.26	3.00e-127	449.00
IUUC-Cja-018950	Callithrix jacchus	87.96	0.00e+00	2146.00
IUUC-Cfa-020299	Canis familiaris	88.30	0.00e+00	2322.00
IUUC-Cpo-021943	Cavia porcellus	87.38	0.00e+00	2293.00
IUUC-Csa-023285	Chlorocebus sabaeus	86.70	0.00e+00	2284.00
IUUC-Cho-025006	Choloepus hoffmanni	80.77	0.00e+00	1986.00
IUUC-Cin-025145	Ciona intestinalis	40.33	0.00e+00	704.00
IUUC-Csv-025839	Ciona savignyi	40.69	0.00e+00	773.00
IUUC-Dre-027959	Danio rerio	81.40	0.00e+00	2070.00
IUUC-Dno-030023	Dasypus novemcinctus	85.06	0.00e+00	2201.00
IUUC-Dor-030994	Dipodomys ordii	85.01	0.00e+00	845.00
IUUC-Dme-031604	Drosophila melanogaster	49.39	9.00e-147	514.00
IUUC-Ete-032596	Echinops telfairi	72.88	0.00e+00	732.00
IUUC-Eca-033913	Equus caballus	87.68	0.00e+00	2318.00
IUUC-Eeu-034518	Erinaceus europaeus	80.63	0.00e+00	1935.00
IUUC-Fca-035997	Felis catus	87.41	0.00e+00	2334.00
IUUC-Fal-037088	Ficedula albicollis	91.11	0.00e+00	2103.00
IUUC-Gmo-038920	Gadus morhua	77.42	0.00e+00	2004.00
IUUC-Gga-040953	Gallus gallus	90.62	0.00e+00	2377.00
IUUC-Gac-042400	Gasterosteus aculeatus	77.64	0.00e+00	1981.00
IUUC-Ggo-044820	Gorilla gorilla	86.03	0.00e+00	2244.00
IUUC-Hsa-046634	Homo sapiens	87.72	0.00e+00	2325.00
IUUC-Lch-050440	Latimeria chalumnae	85.47	0.00e+00	2264.00
IUUC-Loc-051904	Lepisosteus oculatus	83.86	0.00e+00	2208.00
IUUC-Laf-053760	Loxodonta africana	87.22	0.00e+00	2347.00
IUUC-Mcc-054637	Macaca mulatta	87.86	0.00e+00	2332.00
IUUC-Meu-056904	Macropus eugenii	88.91	0.00e+00	1575.00
IUUC-Mga-059556	Meleagris gallopavo	90.10	0.00e+00	2333.00
IUUC-Mmr-061192	Microcebus murinus	88.01	0.00e+00	2331.00
IUUC-Mdo-061929	Monodelphis domestica	88.74	0.00e+00	2372.00
IUUC-Mmu-063726	Mus musculus	86.77	0.00e+00	2335.00
IUUC-Mpu-066014	Mustela putorius furo	87.96	0.00e+00	2306.00
IUUC-Mlu-067232	Myotis lucifugus	87.13	0.00e+00	2291.00
IUUC-Nle-069619	Nomascus leucogenys	86.56	0.00e+00	2279.00
IUUC-Opr-070224	Ochotona princeps	82.90	0.00e+00	1002.00
IUUC-Ont-071384	Oreochromis niloticus	80.24	0.00e+00	2041.00
IUUC-Oan-073208	Ornithorhynchus anatinus	84.71	0.00e+00	2268.00
IUUC-Ocu-074285	Oryctolagus cuniculus	88.01	0.00e+00	2330.00
IUUC-Ola-087051	Oryzias latipes	79.10	0.00e+00	1976.00
IUUC-Oga-088928	Otolemur garnettii	87.97	0.00e+00	2307.00
IUUC-Oar-090215	Ovis aries	87.29	0.00e+00	2315.00
IUUC-Ptr-091035	Pan troglodytes	87.79	0.00e+00	2329.00
IUUC-Pan-092377	Papio anubis	87.31	0.00e+00	2283.00
IUUC-Pfo-096722	Poecilia formosa	78.96	0.00e+00	2020.00
IUUC-Pab-098723	Pongo abelii	87.72	0.00e+00	2328.00
IUUC-Pca-100105	Procavia capensis	82.83	0.00e+00	2112.00
IUUC-Pva-102514	Pteropus vampyrus	89.17	0.00e+00	886.00
IUUC-Rno-105384	Rattus norvegicus	86.56	0.00e+00	2282.00
IUUC-Sha-106982	Sarcophilus harrisii	85.47	0.00e+00	2326.00
IUUC-Sar-113723	Sorex araneus	80.18	0.00e+00	866.00
IUUC-Ssc-115671	Sus scrofa	88.39	0.00e+00	1838.00
IUUC-Tgu-116722	Taeniopygia guttata	88.86	0.00e+00	2340.00
IUUC-Tru-118380	Takifugu rubripes	78.02	0.00e+00	2047.00
IUUC-Tsy-119646	Tarsius syrichta	81.51	0.00e+00	2092.00
IUUC-Tni-120762	Tetraodon nigroviridis	78.08	0.00e+00	2072.00
IUUC-Tbe-127861	Tupaia belangeri	86.17	0.00e+00	2128.00
IUUC-Ttr-129254	Tursiops truncatus	80.02	0.00e+00	1288.00
IUUC-Vpa-130141	Vicugna pacos	89.21	0.00e+00	1092.00
IUUC-Xtr-132700	Xenopus tropicalis	80.88	0.00e+00	2202.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence