iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059722

UUCD1 version

UUC-MeG-00390

Ensembl Protein ID

ENSMGAP00000008681.1

UniProt Accession

G1N8M7; G1N8M7_MELGA

Protein Name

Uncharacterized protein

Gene Name

WSB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000008438.1	ENSMGAT00000009481.1	ENSMGAP00000008681.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.90e-14	51.2	375	420
E3 adaptor/Cullin RING/DCX/DWD	2.30e-32	109.4	169	203
UBD/Beta-Prp	2.30e-46	158.0	134	379

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
           +++w +++++ SLqhLCR+aIrr +++ ++   + LP+P++  ++L y+
   Q: 375  VYFWATPRQVSSLQHLCRMAIRRVMPTSQV---KNLPIPSKVVEFLCYQ 420
           689************************777...*************987 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Ht+ v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 169  HTEVVRDLTFaPDgsLILVSASRDKTLRVWDLKDD 203
           9**********8865668*************9987 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
            kf +d+ llatg  +g+ik+wdv tgkll  l +h++ v++++f pdg+ ilv++s+D+t++vwdl+ +g ++ +lkgh++ v+ ++f
   Q: 134  FKFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLMDHTEVVRDLTFAPDGSlILVSASRDKTLRVWDLKdDGNMMKVLKGHQNWVYGCAF 222
           68899999***********************************************************9899****************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp+++ l s ++ + + +wd+++++ ++  l+gh+  v   +++pdg ll+++s+D+ v +Wd   g +l ++             g++
   Q: 223  SPDSSILCSVGASKAVFLWDMDKYSMIR-KLEGHHNDVVACEFSPDGALLATASYDTRVYVWDPYVGVILMEFghlfppptpifaGGAN 310
           ****************************.999999999999*******************************************9888* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
           ++ v+s+sf+++g +++s ++d+ +++w + ++     + +  +n ++  fs ++  l+ g++Dgs+++W 
   Q: 311  DRWVRSVSFSHDGLHIASLADDKMIRFWRIDEE--YPVQVAPLNNGLCCTFSTDGSVLAAGTQDGSVYFWA 379
           ******************************998..68899******************************2 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

PSTAALQVMN QKAARSRAVG ELLAPTSPFD KKCGRENWTV AFAPDGSYFA WSQGHRIVKL 60
VPWSQCLTNF LLHGTKNVAN SASTRLSRQN SDGSQRNKPC EHIIDCGDIV WSLAFGSSVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCTCCACAG CTGCTTTACA AGTGATGAAC CAGAAAGCAG TTGAGTAACA CGCTGCCTGG 60
TTCCTTGTAA CATCTTAAAA TACCTTAATT AATTTTGAAA TGGAATTTCC TCTTTGTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	88.67	0.00e+00	764.00
IUUC-Apl-003903	Anas platyrhynchos	97.30	0.00e+00	834.00
IUUC-Aca-005214	Anolis carolinensis	78.28	0.00e+00	693.00
IUUC-Ame-011740	Astyanax mexicanus	74.15	0.00e+00	662.00
IUUC-Bta-013475	Bos taurus	87.95	0.00e+00	763.00
IUUC-Cja-019053	Callithrix jacchus	88.16	0.00e+00	778.00
IUUC-Cfa-020103	Canis familiaris	88.43	0.00e+00	761.00
IUUC-Cpo-022438	Cavia porcellus	88.19	0.00e+00	780.00
IUUC-Csa-024062	Chlorocebus sabaeus	88.19	0.00e+00	782.00
IUUC-Cho-024334	Choloepus hoffmanni	77.83	0.00e+00	647.00
IUUC-Cin-025590	Ciona intestinalis	40.95	1.00e-80	293.00
IUUC-Csv-026023	Ciona savignyi	40.19	2.00e-79	289.00
IUUC-Dre-028089	Danio rerio	74.64	0.00e+00	671.00
IUUC-Dno-029436	Dasypus novemcinctus	85.67	0.00e+00	641.00
IUUC-Dor-031107	Dipodomys ordii	81.69	0.00e+00	682.00
IUUC-Ete-032326	Echinops telfairi	87.71	0.00e+00	746.00
IUUC-Eca-033401	Equus caballus	88.46	0.00e+00	765.00
IUUC-Eeu-034520	Erinaceus europaeus	86.27	0.00e+00	771.00
IUUC-Fca-036386	Felis catus	87.95	0.00e+00	762.00
IUUC-Fal-036616	Ficedula albicollis	91.67	0.00e+00	795.00
IUUC-Gmo-039335	Gadus morhua	73.22	0.00e+00	629.00
IUUC-Gga-040856	Gallus gallus	96.63	0.00e+00	842.00
IUUC-Gac-042140	Gasterosteus aculeatus	72.55	0.00e+00	645.00
IUUC-Ggo-044619	Gorilla gorilla	87.95	0.00e+00	781.00
IUUC-Hsa-046300	Homo sapiens	87.95	0.00e+00	779.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	87.95	0.00e+00	778.00
IUUC-Lch-049550	Latimeria chalumnae	82.08	1.00e-173	602.00
IUUC-Loc-051769	Lepisosteus oculatus	76.57	0.00e+00	673.00
IUUC-Laf-054576	Loxodonta africana	87.95	0.00e+00	759.00
IUUC-Mcc-054666	Macaca mulatta	89.31	2.00e-143	501.00
IUUC-Meu-055989	Macropus eugenii	86.86	0.00e+00	642.00
IUUC-Mmr-060970	Microcebus murinus	88.67	0.00e+00	761.00
IUUC-Mdo-062249	Monodelphis domestica	74.64	2.00e-178	617.00
IUUC-Mmu-063742	Mus musculus	83.33	0.00e+00	743.00
IUUC-Mpu-066518	Mustela putorius furo	87.71	0.00e+00	781.00
IUUC-Mlu-068063	Myotis lucifugus	88.19	0.00e+00	756.00
IUUC-Nle-069561	Nomascus leucogenys	87.95	0.00e+00	781.00
IUUC-Opr-071158	Ochotona princeps	85.99	0.00e+00	759.00
IUUC-Ont-072542	Oreochromis niloticus	71.84	0.00e+00	640.00
IUUC-Oan-073217	Ornithorhynchus anatinus	88.92	0.00e+00	777.00
IUUC-Ocu-074251	Oryctolagus cuniculus	89.68	0.00e+00	764.00
IUUC-Ola-086549	Oryzias latipes	71.84	0.00e+00	644.00
IUUC-Oga-088382	Otolemur garnettii	88.92	0.00e+00	771.00
IUUC-Oar-090263	Ovis aries	86.02	0.00e+00	761.00
IUUC-Ptr-090922	Pan troglodytes	88.19	0.00e+00	782.00
IUUC-Pan-092518	Papio anubis	88.19	0.00e+00	782.00
IUUC-Psi-093512	Pelodiscus sinensis	91.79	0.00e+00	805.00
IUUC-Pma-094324	Petromyzon marinus	57.38	3.00e-133	468.00
IUUC-Pfo-096264	Poecilia formosa	73.30	0.00e+00	645.00
IUUC-Pab-098018	Pongo abelii	86.27	0.00e+00	764.00
IUUC-Pca-101034	Procavia capensis	87.96	0.00e+00	727.00
IUUC-Pva-102862	Pteropus vampyrus	84.34	0.00e+00	698.00
IUUC-Rno-106116	Rattus norvegicus	84.34	0.00e+00	754.00
IUUC-Sha-106952	Sarcophilus harrisii	87.47	0.00e+00	746.00
IUUC-Sar-113211	Sorex araneus	80.19	1.00e-145	508.00
IUUC-Ssc-116440	Sus scrofa	88.67	0.00e+00	764.00
IUUC-Tgu-116675	Taeniopygia guttata	93.38	0.00e+00	802.00
IUUC-Tru-118295	Takifugu rubripes	72.09	3.00e-180	624.00
IUUC-Tsy-118916	Tarsius syrichta	77.11	0.00e+00	641.00
IUUC-Tni-120302	Tetraodon nigroviridis	69.93	4.00e-177	613.00
IUUC-Tbe-127416	Tupaia belangeri	77.40	0.00e+00	632.00
IUUC-Ttr-128185	Tursiops truncatus	88.19	0.00e+00	761.00
IUUC-Xtr-132465	Xenopus tropicalis	84.02	0.00e+00	738.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence