iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004012

Ensembl Protein ID

ENSAPLP00000016079.1

UniProt Accession

U3J9A1; U3J9A1_ANAPL

Genbank Protein ID

ENSAPLP00000016079

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01073119

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000016176.1	ENSAPLT00000016892.1	ENSAPLP00000016079.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.20e-39	130.1	222	259
UBD/Beta-Prp	9.10e-60	202.1	89	383

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           Ht  v+c++f +d ++++++s Dg+i ++D +tg +++
   Q: 222  HTRFVNCVRFsPDgNRFATASADGQIFIYDGKTGEKVC 259
           9999*******999****************99998765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlk 91
           ++h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++
   Q: 89   TEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDLAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEIT 177
           4566667778*************************998777742334567***********99999999887777777789******** PP
   S: 92   ghedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tg 177
           gh++ + s+++ +++ ++l++Gs+d+ +  ++ +  +    tls h+++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l   +
   Q: 178  GHNKVINSVDIKQTRpYRLATGSDDNCAAFFEGPPFKFKF-TLSDHTRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALggGK 265
           *************999*******************99999.********************************************9955 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvks.vrfspnderlvsgssDgsiriWdlrs.gdllktlqlhn 264
           +h++ +y +s+++++ +l+s+s d+t k+wd+ ++++v+t+n  ++   + +  + ++++l++ s  g i+  d+ + +++l+++++h 
   Q: 266  AHDGGIYAISWSPDSSQLLSASGDKTAKIWDVGANSVVNTFNMGSNVLDQqLGCLWQKDHLLTISLSGYINYLDKNNpNKPLRVIKGHS 354
           6****************************************98776655414444688889999999*****98765367888888888 PP
   S: 265  ssvisvavlsfg.dnvlvlgsedskvniw 292
           +s+ + +v++ g ++++++gs+d+ +ni+
   Q: 355  KSIQCLTVHKNGgKSYIYSGSNDGHINIL 383
           9999999876666999***********97 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

PLRWRQEHSV ARCCPRMRKA PGDAQTASGR ERAKMPYEIK KVFASLPQVE RGVSKILGGD 60
PKGNNFLYTN GKCVVIRNAD NPAIADIYTE HAHQVVVAKY APSGFYIASG DVSGKLRIWD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCTCAGAT GGCGGCAGGA ACATTCGGTA GCGCGGTGCT GCCCGCGCAT GCGCAAGGCG 60
CCGGGTGACG CCCAAACCCN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	35.94	3.00e-82	298.00
IUUC-Aml-002368	Ailuropoda melanoleuca	85.51	0.00e+00	1069.00
IUUC-Atr-003160	Amborella trichopoda	37.81	5.00e-114	404.00
IUUC-Aca-004707	Anolis carolinensis	83.86	0.00e+00	1051.00
IUUC-Aly-006465	Arabidopsis lyrata	39.28	2.00e-113	402.00
IUUC-Ath-006740	Arabidopsis thaliana	39.12	4.00e-112	398.00
IUUC-Ago-007920	Ashbya gossypii	27.86	9.00e-71	261.00
IUUC-Acl-008262	Aspergillus clavatus	36.32	1.00e-105	376.00
IUUC-Afl-008471	Aspergillus flavus	30.33	4.00e-65	242.00
IUUC-Afu-008989	Aspergillus fumigatus	38.02	5.00e-95	341.00
IUUC-Ani-009167	Aspergillus nidulans	37.15	5.00e-109	387.00
IUUC-Ang-009595	Aspergillus niger	37.63	2.00e-99	356.00
IUUC-Aor-009908	Aspergillus oryzae	36.52	5.00e-96	344.00
IUUC-Ate-010580	Aspergillus terreus	37.19	4.00e-101	363.00
IUUC-Ame-011269	Astyanax mexicanus	60.25	3.00e-129	454.00
IUUC-Bgr-011996	Blumeria graminis	33.50	1.00e-101	363.00
IUUC-Bta-013278	Bos taurus	89.11	0.00e+00	1114.00
IUUC-Bci-013925	Botrytis cinerea	35.23	2.00e-103	369.00
IUUC-Bdi-014659	Brachypodium distachyon	36.02	4.00e-104	371.00
IUUC-Bol-016043	Brassica oleracea	36.33	3.00e-106	379.00
IUUC-Bra-017139	Brassica rapa	38.20	7.00e-110	390.00
IUUC-Cel-018417	Caenorhabditis elegans	40.27	3.00e-118	418.00
IUUC-Cja-019952	Callithrix jacchus	86.68	0.00e+00	1068.00
IUUC-Cfa-020225	Canis familiaris	88.61	0.00e+00	1087.00
IUUC-Cpo-021900	Cavia porcellus	86.86	0.00e+00	1080.00
IUUC-Csa-023028	Chlorocebus sabaeus	87.62	0.00e+00	1074.00
IUUC-Cho-025030	Choloepus hoffmanni	64.43	0.00e+00	706.00
IUUC-Cin-025152	Ciona intestinalis	54.83	3.00e-81	294.00
IUUC-Csv-025986	Ciona savignyi	36.99	3.00e-88	318.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	37.56	3.00e-110	392.00
IUUC-Cne-026814	Cryptococcus neoformans	35.65	9.00e-98	350.00
IUUC-Dre-027498	Danio rerio	81.03	2.00e-96	344.00
IUUC-Dno-029383	Dasypus novemcinctus	86.80	0.00e+00	1057.00
IUUC-Dor-030633	Dipodomys ordii	85.87	0.00e+00	986.00
IUUC-Dse-031526	Dothistroma septosporum	37.64	1.00e-108	386.00
IUUC-Dme-031597	Drosophila melanogaster	47.52	2.00e-163	568.00
IUUC-Ete-032780	Echinops telfairi	79.67	0.00e+00	987.00
IUUC-Eca-034306	Equus caballus	86.36	0.00e+00	1045.00
IUUC-Eeu-034531	Erinaceus europaeus	69.40	4.00e-125	441.00
IUUC-Fca-036301	Felis catus	87.69	0.00e+00	1093.00
IUUC-Fal-037361	Ficedula albicollis	94.71	0.00e+00	1178.00
IUUC-Fox-037924	Fusarium oxysporum	35.14	3.00e-97	348.00
IUUC-Fso-038199	Fusarium solani	34.32	1.00e-92	333.00
IUUC-Gmo-039238	Gadus morhua	71.50	0.00e+00	878.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.29	1.00e-95	343.00
IUUC-Gga-040235	Gallus gallus	96.54	0.00e+00	1173.00
IUUC-Gac-042363	Gasterosteus aculeatus	71.50	0.00e+00	918.00
IUUC-Gma-044189	Glycine max	38.16	5.00e-113	401.00
IUUC-Ggo-044632	Gorilla gorilla	85.67	0.00e+00	1040.00
IUUC-Hsa-045792	Homo sapiens	87.29	0.00e+00	1074.00
IUUC-Hvu-047517	Hordeum vulgare	36.17	1.00e-107	383.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	88.02	0.00e+00	1068.00
IUUC-Kpa-049183	Komagataella pastoris	33.11	3.00e-87	315.00
IUUC-Lch-050428	Latimeria chalumnae	75.89	0.00e+00	983.00
IUUC-Lpe-051306	Leersia perrieri	36.72	7.00e-110	390.00
IUUC-Loc-052096	Lepisosteus oculatus	72.49	0.00e+00	878.00
IUUC-Lma-053313	Leptosphaeria maculans	38.57	2.00e-110	395.00
IUUC-Laf-054060	Loxodonta africana	86.92	0.00e+00	1087.00
IUUC-Mcc-055619	Macaca mulatta	85.76	0.00e+00	1045.00
IUUC-Meu-056689	Macropus eugenii	77.27	6.00e-179	620.00
IUUC-Mor-056940	Magnaporthe oryzae	35.82	6.00e-96	344.00
IUUC-Mpo-057557	Magnaporthe poae	30.31	2.00e-68	253.00
IUUC-Mtr-057922	Medicago truncatula	36.39	2.00e-110	392.00
IUUC-Mla-059103	Melampsora laricipopulina	32.75	7.00e-74	271.00
IUUC-Mga-060150	Meleagris gallopavo	96.36	0.00e+00	1162.00
IUUC-Mvi-060448	Microbotryum violaceum	31.33	5.00e-74	271.00
IUUC-Mmr-061226	Microcebus murinus	88.04	0.00e+00	1087.00
IUUC-Mdo-062674	Monodelphis domestica	89.11	0.00e+00	1101.00
IUUC-Mmu-064170	Mus musculus	87.95	0.00e+00	1097.00
IUUC-Mac-065124	Musa acuminata	38.69	4.00e-113	401.00
IUUC-Mpu-066001	Mustela putorius furo	84.90	0.00e+00	1071.00
IUUC-Mlu-067253	Myotis lucifugus	88.19	0.00e+00	1083.00
IUUC-Nfi-068550	Neosartorya fischeri	37.76	2.00e-108	386.00
IUUC-Ncr-068948	Neurospora crassa	36.33	6.00e-111	394.00
IUUC-Nle-070115	Nomascus leucogenys	85.20	0.00e+00	957.00
IUUC-Opr-070254	Ochotona princeps	84.77	0.00e+00	1022.00
IUUC-Ont-071666	Oreochromis niloticus	75.58	0.00e+00	954.00
IUUC-Oan-073594	Ornithorhynchus anatinus	85.89	6.00e-153	532.00
IUUC-Ocu-074824	Oryctolagus cuniculus	85.81	0.00e+00	1046.00
IUUC-Oba-075010	Oryza barthii	36.66	4.00e-109	388.00
IUUC-Obr-076364	Oryza brachyantha	38.56	1.00e-112	399.00
IUUC-Ogl-077019	Oryza glaberrima	36.66	4.00e-109	388.00
IUUC-Ogu-078496	Oryza glumaepatula	36.66	4.00e-109	388.00
IUUC-Oin-080116	Oryza indica	36.82	2.00e-109	389.00
IUUC-Olo-080290	Oryza longistaminata	36.66	7.00e-109	387.00
IUUC-Ome-081969	Oryza meridionalis	36.66	5.00e-109	387.00
IUUC-Oni-082075	Oryza nivara	36.66	4.00e-109	388.00
IUUC-Opu-083959	Oryza punctata	36.89	2.00e-111	396.00
IUUC-Oru-084711	Oryza rufipogon	36.66	4.00e-109	388.00
IUUC-Osa-085958	Oryza sativa	36.82	2.00e-109	389.00
IUUC-Ola-086968	Oryzias latipes	74.96	0.00e+00	941.00
IUUC-Oga-089108	Otolemur garnettii	85.69	0.00e+00	1109.00
IUUC-Oar-089986	Ovis aries	82.46	0.00e+00	1023.00
IUUC-Ptr-091281	Pan troglodytes	87.33	0.00e+00	1063.00
IUUC-Pan-092585	Papio anubis	87.62	0.00e+00	1073.00
IUUC-Psi-093811	Pelodiscus sinensis	90.03	0.00e+00	1126.00
IUUC-Pma-094542	Petromyzon marinus	69.69	0.00e+00	875.00
IUUC-Pno-095086	Phaeosphaeria nodorum	36.71	1.00e-103	370.00
IUUC-Ppa-095876	Physcomitrella patens	36.66	4.00e-109	388.00
IUUC-Pfo-096973	Poecilia formosa	75.41	0.00e+00	973.00
IUUC-Pab-098391	Pongo abelii	87.13	0.00e+00	1071.00
IUUC-Pop-098850	Populus trichocarpa	37.97	2.00e-112	399.00
IUUC-Pca-100257	Procavia capensis	53.67	1.00e-78	286.00
IUUC-Ppe-101578	Prunus persica	38.73	1.00e-113	402.00
IUUC-Pva-102872	Pteropus vampyrus	83.03	0.00e+00	1040.00
IUUC-Pgr-103593	Puccinia graminis	33.28	2.00e-78	286.00
IUUC-Pte-104365	Pyrenophora teres	38.44	5.00e-106	378.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	38.11	2.00e-108	386.00
IUUC-Rno-105737	Rattus norvegicus	88.28	0.00e+00	1105.00
IUUC-Sce-106383	Saccharomyces cerevisiae	28.84	2.00e-65	243.00
IUUC-Sha-107084	Sarcophilus harrisii	86.45	0.00e+00	960.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	35.19	1.00e-106	380.00
IUUC-Spo-108309	Schizosaccharomyces pombe	32.90	4.00e-92	332.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	35.39	3.00e-104	372.00
IUUC-Smo-109255	Selaginella moellendorffii	36.97	1.00e-102	367.00
IUUC-Sit-109962	Setaria italica	37.54	2.00e-111	396.00
IUUC-Sly-110897	Solanum lycopersicum	38.92	4.00e-115	408.00
IUUC-Stu-111971	Solanum tuberosum	38.59	4.00e-114	404.00
IUUC-Sar-113415	Sorex araneus	70.85	7.00e-108	384.00
IUUC-Sbi-114857	Sorghum bicolor	37.25	4.00e-109	388.00
IUUC-Sre-114900	Sporisorium reilianum	34.74	3.00e-89	322.00
IUUC-Tgu-117256	Taeniopygia guttata	96.35	0.00e+00	1192.00
IUUC-Tru-117871	Takifugu rubripes	70.08	0.00e+00	872.00
IUUC-Tsy-119172	Tarsius syrichta	92.08	5.00e-134	470.00
IUUC-Tni-120339	Tetraodon nigroviridis	69.90	0.00e+00	898.00
IUUC-Tca-121609	Theobroma cacao	38.17	5.00e-112	398.00
IUUC-Tre-122076	Trichoderma reesei	35.25	3.00e-90	325.00
IUUC-Tvi-122528	Trichoderma virens	33.50	9.00e-92	330.00
IUUC-Tae-124549	Triticum aestivum	35.90	2.00e-108	386.00
IUUC-Tur-126845	Triticum urartu	35.52	1.00e-80	293.00
IUUC-Tme-127217	Tuber melanosporum	34.99	3.00e-100	358.00
IUUC-Tbe-127526	Tupaia belangeri	85.31	0.00e+00	1048.00
IUUC-Ttr-128898	Tursiops truncatus	80.40	0.00e+00	998.00
IUUC-Uma-129631	Ustilago maydis	32.68	4.00e-90	325.00
IUUC-Vda-129732	Verticillium dahliae	34.93	1.00e-91	330.00
IUUC-Vvi-131217	Vitis vinifera	38.70	1.00e-111	396.00
IUUC-Xtr-132860	Xenopus tropicalis	73.74	0.00e+00	928.00
IUUC-Xma-133830	Xiphophorus maculatus	75.41	0.00e+00	973.00
IUUC-Yli-134335	Yarrowia lipolytica	32.68	6.00e-70	258.00
IUUC-Zma-135907	Zea mays	37.05	2.00e-110	392.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence