iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059713

Ensembl Protein ID

ENSMGAP00000013296.2

UniProt Accession

G1NJ20; G1NJ20_MELGA

Protein Name

Uncharacterized protein

Gene Name

LATS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000012618.2	ENSMGAT00000014200.2	ENSMGAP00000013296.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.40e-08	34.4	103	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l+ l++ GFd++ ++qaLr++ n ++eaA+e++ 
   Q: 103  NRQMLQDLQAAGFDEDMVIQALRQTnNRSIEAAIEFIS 140
           669*********************99*********975 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MKRTEKPEGY RQMRPKTFPA SNYTGSSQQM LQEIRESLRN LPKPSDAAKA DLSMGKMSSE 60
DPRQGRNPPK FVTYHKVLQE IRNSLLPFAN ETTSAVKGTS EVNRQMLQDL QAAGFDEDMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAGAA CTGAGAAGCC AGAAGGTTAC AGACAAATGA GGCCTAAGAC TTTTCCTGCC 60
AGTAACTATA CTGGCAGCAG CCAGCAGATG CTACAGGAAA TACGAGAGAG CCTCAGGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR028741--LATS1/Warts
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0051220--P:cytoplasmic sequestering of protein
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0030216--P:keratinocyte differentiation
GO:0007067--P:mitotic nuclear division
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0030833--P:regulation of actin filament polymerization
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0000819--P:sister chromatid segregation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001895	Ailuropoda melanoleuca	83.06	0.00e+00	1772.00
IUUC-Apl-003278	Anas platyrhynchos	95.09	0.00e+00	2018.00
IUUC-Aca-005319	Anolis carolinensis	82.63	0.00e+00	1776.00
IUUC-Ame-011324	Astyanax mexicanus	84.56	0.00e+00	940.00
IUUC-Bta-013438	Bos taurus	82.63	0.00e+00	1722.00
IUUC-Cel-018517	Caenorhabditis elegans	50.11	7.00e-129	454.00
IUUC-Cja-019072	Callithrix jacchus	84.21	0.00e+00	1825.00
IUUC-Cfa-021267	Canis familiaris	83.32	0.00e+00	1786.00
IUUC-Cpo-021496	Cavia porcellus	79.53	0.00e+00	1456.00
IUUC-Csa-023255	Chlorocebus sabaeus	84.30	0.00e+00	1801.00
IUUC-Cho-024461	Choloepus hoffmanni	96.13	0.00e+00	751.00
IUUC-Cin-025264	Ciona intestinalis	65.85	3.00e-140	491.00
IUUC-Dre-028034	Danio rerio	82.71	0.00e+00	922.00
IUUC-Dno-029888	Dasypus novemcinctus	82.19	0.00e+00	1774.00
IUUC-Dor-030144	Dipodomys ordii	72.89	0.00e+00	1486.00
IUUC-Dme-031656	Drosophila melanogaster	72.49	0.00e+00	652.00
IUUC-Ete-032813	Echinops telfairi	87.23	0.00e+00	1134.00
IUUC-Eca-033781	Equus caballus	83.16	0.00e+00	1766.00
IUUC-Eeu-035007	Erinaceus europaeus	81.40	0.00e+00	1736.00
IUUC-Fca-036142	Felis catus	78.75	0.00e+00	1658.00
IUUC-Fal-036626	Ficedula albicollis	94.30	0.00e+00	2019.00
IUUC-Gmo-038688	Gadus morhua	84.32	0.00e+00	768.00
IUUC-Gga-040553	Gallus gallus	97.98	0.00e+00	2087.00
IUUC-Gac-042031	Gasterosteus aculeatus	64.02	0.00e+00	1298.00
IUUC-Ggo-045242	Gorilla gorilla	84.04	0.00e+00	1809.00
IUUC-Hsa-046081	Homo sapiens	83.77	0.00e+00	1801.00
IUUC-Itr-048668	Ictidomys tridecemlineatus	84.07	0.00e+00	1541.00
IUUC-Lch-049425	Latimeria chalumnae	78.78	0.00e+00	1686.00
IUUC-Loc-052418	Lepisosteus oculatus	66.98	0.00e+00	1374.00
IUUC-Laf-053710	Loxodonta africana	83.17	0.00e+00	1757.00
IUUC-Mcc-055079	Macaca mulatta	84.04	0.00e+00	1793.00
IUUC-Mmr-061728	Microcebus murinus	84.30	0.00e+00	1783.00
IUUC-Mdo-061942	Monodelphis domestica	82.15	0.00e+00	1765.00
IUUC-Mmu-063504	Mus musculus	82.70	0.00e+00	1725.00
IUUC-Mpu-066034	Mustela putorius furo	83.33	0.00e+00	1782.00
IUUC-Mlu-067986	Myotis lucifugus	83.30	0.00e+00	1769.00
IUUC-Nle-069202	Nomascus leucogenys	84.21	0.00e+00	1805.00
IUUC-Opr-070801	Ochotona princeps	89.92	0.00e+00	1187.00
IUUC-Ont-072487	Oreochromis niloticus	60.24	0.00e+00	1244.00
IUUC-Oan-073128	Ornithorhynchus anatinus	83.10	0.00e+00	1551.00
IUUC-Ocu-073998	Oryctolagus cuniculus	83.82	0.00e+00	1296.00
IUUC-Ola-086858	Oryzias latipes	62.13	0.00e+00	1195.00
IUUC-Oga-088874	Otolemur garnettii	82.46	0.00e+00	1744.00
IUUC-Oar-089236	Ovis aries	83.00	0.00e+00	1736.00
IUUC-Ptr-091425	Pan troglodytes	84.04	0.00e+00	1808.00
IUUC-Pan-091851	Papio anubis	84.30	0.00e+00	1803.00
IUUC-Psi-093825	Pelodiscus sinensis	88.36	0.00e+00	1571.00
IUUC-Pfo-096326	Poecilia formosa	60.51	0.00e+00	1179.00
IUUC-Pab-097815	Pongo abelii	84.12	0.00e+00	1809.00
IUUC-Pva-102836	Pteropus vampyrus	81.40	0.00e+00	1669.00
IUUC-Ptt-103762	Puccinia triticina	38.52	3.00e-92	333.00
IUUC-Rno-106053	Rattus norvegicus	83.25	0.00e+00	1789.00
IUUC-Sha-106843	Sarcophilus harrisii	83.07	0.00e+00	1793.00
IUUC-Sar-113649	Sorex araneus	83.00	0.00e+00	1362.00
IUUC-Ssc-115486	Sus scrofa	93.33	0.00e+00	803.00
IUUC-Tgu-116903	Taeniopygia guttata	93.60	0.00e+00	2001.00
IUUC-Tru-118760	Takifugu rubripes	63.62	0.00e+00	1308.00
IUUC-Tsy-119361	Tarsius syrichta	82.60	0.00e+00	1528.00
IUUC-Tni-120058	Tetraodon nigroviridis	82.16	0.00e+00	872.00
IUUC-Tbe-127681	Tupaia belangeri	84.27	0.00e+00	1368.00
IUUC-Ttr-128652	Tursiops truncatus	82.80	0.00e+00	1477.00
IUUC-Vpa-130538	Vicugna pacos	82.54	0.00e+00	1758.00
IUUC-Xtr-132895	Xenopus tropicalis	72.18	0.00e+00	1266.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence