iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-002428

Ensembl Protein ID

ENSAMEP00000001660.1

UniProt Accession

G1L450; G1L450_AILME

Genbank Protein ID

ENSAMEP00000001660

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01140201

Gene Name

DENND3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000001580.1	ENSAMET00000001723.1	ENSAMEP00000001660.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.20e-06	26.5	1028	1065

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf....sd.tllvsGsdDgtikvWDlrtgv 34
           H ++vt+la     ++   + s+s Dgt+  W++++ +
   Q: 1028 HRSGVTGLAVqhgtPSaSKVYSCSADGTVLAWNVSSLR 1065
           99******99999977889**************98765 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

KQGVSSPSSL DPEVLSVFVP PFVSKEDSQT AGAPSATLSK TRRRSFRKKR DKPKTEPWKG 60
LPPEDISVPN GVDLLALPQL CFPGGMYVAS EPKEDCVHFL VLTDVCGNRT YAVVAQYYRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGCAGGGGG TCAGCAGCCC CTCTTCTCTT GATCCAGAGG TCCTGTCCGT TTTTGTGCCT 60
CCTTTCGTCA GTAAGGAGGA CAGTCAGACG GCTGGCGCCC CCTCTGCGAC TCTGAGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005112--dDENN_dom
IPR001194--DENN_dom
IPR005113--uDENN_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50947--DDENN
PS50211--DENN
PS50946--UDENN
PS00678--WD_REPEATS_1
PS50294--WD_REPEATS_REGION

Pfam

PF02141--DENN

SMART

SM00801--dDENN
SM00799--DENN
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0044257--P:cellular protein catabolic process
GO:0008333--P:endosome to lysosome transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011614	Astyanax mexicanus	54.03	0.00e+00	1345.00
IUUC-Cfa-021105	Canis familiaris	89.85	0.00e+00	2227.00
IUUC-Dor-030471	Dipodomys ordii	78.55	0.00e+00	1021.00
IUUC-Gmo-039067	Gadus morhua	52.25	4.00e-109	389.00
IUUC-Gac-041903	Gasterosteus aculeatus	51.90	0.00e+00	1224.00
IUUC-Hsa-046572	Homo sapiens	78.10	0.00e+00	1814.00
IUUC-Loc-052634	Lepisosteus oculatus	57.66	0.00e+00	1471.00
IUUC-Mcc-055358	Macaca mulatta	79.36	0.00e+00	1915.00
IUUC-Mmr-060775	Microcebus murinus	80.10	0.00e+00	2019.00
IUUC-Mmu-063704	Mus musculus	77.92	0.00e+00	1932.00
IUUC-Ont-072676	Oreochromis niloticus	51.74	0.00e+00	1255.00
IUUC-Oni-082213	Oryza nivara	23.33	5.00e-18	87.00
IUUC-Olu-087744	Ostreococcus lucimarinus	29.23	2.00e-10	62.00
IUUC-Oga-088682	Otolemur garnettii	80.45	0.00e+00	1993.00
IUUC-Ptr-090684	Pan troglodytes	77.96	0.00e+00	1795.00
IUUC-Pan-092645	Papio anubis	79.71	0.00e+00	1917.00
IUUC-Pfo-096475	Poecilia formosa	52.47	0.00e+00	1254.00
IUUC-Rno-105167	Rattus norvegicus	78.98	0.00e+00	1900.00
IUUC-Ssc-115459	Sus scrofa	78.23	4.00e-111	393.00
IUUC-Tru-118373	Takifugu rubripes	28.33	1.00e-14	75.50
IUUC-Tni-119750	Tetraodon nigroviridis	27.92	4.00e-14	73.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence