iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090684

Ensembl Protein ID

ENSPTRP00000035270.4

UniProt Accession

H2QWS2; H2QWS2_PANTR

Genbank Protein ID

ENSPTRP00000035270

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03064380

Gene Name

DENND3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000020626.5	ENSPTRT00000038148.4	ENSPTRP00000035270.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-07	31.3	985	1021

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf......sdtllvsGsdDgtikvWDlrtg 33
           H +svt+l        +   + s+s Dgt+ vW+++t 
   Q: 985  HCSSVTDLIVqdgqeaP-SDVYSCSMDGTVLVWNVSTL 1021
           89999999656664442.349*************9875 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MRSLRKKREK PRPEQWKGLL GPPRASEPED VAVPGGVDLL TLPQLCFPGG VCVATEPKED 60
CVHFLVLTDV CGNRTYGVVA QYYRPLHDDY CFYNGKTHRE CPGCFVPFAV CVVSRFPYYN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCACTCTCG GTAAAACCCG GATGCGCTCC TTGAGAAAGA AGAGAGAGAA GCCCAGACCA 60
GAGCAGTGGA AGGGCCTCCT GGGGCCCCCC AGAGCGTCAG AGCCTGAGGA TGTCGCCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005112--dDENN_dom
IPR001194--DENN_dom
IPR005113--uDENN_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50947--DDENN
PS50211--DENN
PS50946--UDENN
PS00678--WD_REPEATS_1
PS50294--WD_REPEATS_REGION

Pfam

PF02141--DENN

SMART

SM00801--dDENN
SM00799--DENN
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0044257--P:cellular protein catabolic process
GO:0008333--P:endosome to lysosome transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002428	Ailuropoda melanoleuca	78.08	0.00e+00	1833.00
IUUC-Ame-011614	Astyanax mexicanus	53.78	0.00e+00	1279.00
IUUC-Cfa-021105	Canis familiaris	79.08	0.00e+00	1860.00
IUUC-Csv-025827	Ciona savignyi	24.63	1.00e-06	49.70
IUUC-Dor-030471	Dipodomys ordii	78.55	0.00e+00	999.00
IUUC-Gmo-039067	Gadus morhua	52.25	9.00e-107	381.00
IUUC-Gac-041903	Gasterosteus aculeatus	51.93	0.00e+00	1164.00
IUUC-Hsa-046572	Homo sapiens	97.50	0.00e+00	2212.00
IUUC-Loc-052634	Lepisosteus oculatus	56.62	0.00e+00	1380.00
IUUC-Mcc-055358	Macaca mulatta	90.51	0.00e+00	2096.00
IUUC-Mmr-060775	Microcebus murinus	81.06	0.00e+00	1975.00
IUUC-Mmu-063704	Mus musculus	78.47	0.00e+00	1865.00
IUUC-Ont-072676	Oreochromis niloticus	50.94	0.00e+00	1191.00
IUUC-Oni-082213	Oryza nivara	26.41	4.00e-20	94.00
IUUC-Olu-087744	Ostreococcus lucimarinus	27.34	7.00e-10	60.10
IUUC-Oga-088682	Otolemur garnettii	81.06	0.00e+00	1944.00
IUUC-Pan-092645	Papio anubis	90.36	0.00e+00	2089.00
IUUC-Pfo-096475	Poecilia formosa	53.12	0.00e+00	1178.00
IUUC-Ppe-101883	Prunus persica	22.91	1.00e-19	92.00
IUUC-Rno-105167	Rattus norvegicus	77.73	0.00e+00	1831.00
IUUC-Ssc-115459	Sus scrofa	75.00	8.00e-108	382.00
IUUC-Tru-118373	Takifugu rubripes	23.74	2.00e-15	78.60
IUUC-Tni-119750	Tetraodon nigroviridis	24.18	3.00e-15	77.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence