iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012489

Ensembl Protein ID

ENSBTAP00000053514.2

UniProt Accession

F1MKU1; F1MKU1_BOVIN

Genbank Protein ID

ENSBTAP00000053514

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02021991

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000003366.6	ENSBTAT00000061377.2	ENSBTAP00000053514.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	5.10e-49	164.9	1	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           ++ e+r+ l +++d+vrk+Ld+t++l+ y++++++  +++ i+a +++kg+m+aa l+L++L  +q+egWfr+fl
   Q: 1    MTAEQRRNLHAFRDYVRKILDPTYILS-YMTPWFRDDVVQHIQAKKNNKGPMEAASLFLQVLleLQEEGWFRGFL 74
           5679***********************.*********************************************96 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MTAEQRRNLH AFRDYVRKIL DPTYILSYMT PWFRDDVVQH IQAKKNNKGP MEAASLFLQV 60
LLELQEEGWF RGFLDALQQA GYSGLYEAIE SWDFQKLEKL EEYRLLLKRL QPEFKTTINP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGCAG AGCAGCGGCG GAATTTGCAC GCCTTCCGCG ACTATGTCAG GAAGATCCTG 60
GACCCTACCT ACATCCTGAG CTACATGACC CCCTGGTTTA GGGACGGTGA GTGGTTGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011545--DEAD/DEAH_box_helicase_dom
IPR011029--DEATH-like_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00270--DEAD
PF00271--Helicase_C
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	81.16	0.00e+00	1526.00
IUUC-Apl-003966	Anas platyrhynchos	53.70	0.00e+00	945.00
IUUC-Aca-004499	Anolis carolinensis	47.17	0.00e+00	821.00
IUUC-Ame-011950	Astyanax mexicanus	42.80	0.00e+00	699.00
IUUC-Cel-018230	Caenorhabditis elegans	29.36	3.00e-68	253.00
IUUC-Cja-018716	Callithrix jacchus	79.25	0.00e+00	1474.00
IUUC-Cfa-020269	Canis familiaris	82.42	0.00e+00	1565.00
IUUC-Cpo-022507	Cavia porcellus	72.65	0.00e+00	1351.00
IUUC-Csa-024209	Chlorocebus sabaeus	79.25	0.00e+00	1486.00
IUUC-Cho-025104	Choloepus hoffmanni	71.83	0.00e+00	1145.00
IUUC-Cin-025792	Ciona intestinalis	33.19	4.00e-82	298.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	24.34	6.00e-21	97.10
IUUC-Dno-028954	Dasypus novemcinctus	76.69	0.00e+00	1392.00
IUUC-Eca-034039	Equus caballus	81.91	0.00e+00	1540.00
IUUC-Eeu-035009	Erinaceus europaeus	68.88	0.00e+00	917.00
IUUC-Fca-036169	Felis catus	83.50	0.00e+00	1588.00
IUUC-Fal-037579	Ficedula albicollis	53.58	0.00e+00	924.00
IUUC-Fso-038398	Fusarium solani	24.77	1.00e-19	92.80
IUUC-Ggo-045318	Gorilla gorilla	78.24	0.00e+00	1360.00
IUUC-Hsa-046671	Homo sapiens	80.11	0.00e+00	1471.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	75.59	0.00e+00	1385.00
IUUC-Lch-050461	Latimeria chalumnae	51.81	0.00e+00	897.00
IUUC-Loc-052582	Lepisosteus oculatus	47.60	0.00e+00	832.00
IUUC-Laf-054324	Loxodonta africana	79.64	0.00e+00	1448.00
IUUC-Mcc-055390	Macaca mulatta	78.82	0.00e+00	1472.00
IUUC-Meu-056365	Macropus eugenii	62.43	4.00e-129	455.00
IUUC-Mmr-061407	Microcebus murinus	79.46	0.00e+00	1512.00
IUUC-Mmu-063939	Mus musculus	72.27	0.00e+00	1344.00
IUUC-Mpu-066226	Mustela putorius furo	81.49	0.00e+00	1437.00
IUUC-Mlu-068092	Myotis lucifugus	81.05	0.00e+00	1480.00
IUUC-Opr-070246	Ochotona princeps	65.09	0.00e+00	652.00
IUUC-Oan-072742	Ornithorhynchus anatinus	60.86	0.00e+00	977.00
IUUC-Ocu-073959	Oryctolagus cuniculus	73.55	0.00e+00	1391.00
IUUC-Oga-089173	Otolemur garnettii	77.93	0.00e+00	1436.00
IUUC-Oar-089369	Ovis aries	92.15	0.00e+00	1682.00
IUUC-Ptr-091032	Pan troglodytes	80.11	0.00e+00	1471.00
IUUC-Pan-092383	Papio anubis	79.14	0.00e+00	1475.00
IUUC-Psi-093432	Pelodiscus sinensis	57.07	0.00e+00	1083.00
IUUC-Pma-094367	Petromyzon marinus	41.47	5.00e-115	408.00
IUUC-Pab-098416	Pongo abelii	80.23	0.00e+00	1375.00
IUUC-Pca-101006	Procavia capensis	80.25	0.00e+00	654.00
IUUC-Pva-102966	Pteropus vampyrus	83.37	0.00e+00	1555.00
IUUC-Pgr-103529	Puccinia graminis	26.34	2.00e-27	118.00
IUUC-Rno-105059	Rattus norvegicus	74.71	0.00e+00	884.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	31.63	2.00e-05	46.60
IUUC-Sar-113202	Sorex araneus	66.67	0.00e+00	1021.00
IUUC-Ssc-116120	Sus scrofa	82.41	0.00e+00	1519.00
IUUC-Tgu-117314	Taeniopygia guttata	52.44	0.00e+00	942.00
IUUC-Tsy-119453	Tarsius syrichta	78.67	0.00e+00	826.00
IUUC-Tre-122194	Trichoderma reesei	25.24	4.00e-18	87.80
IUUC-Ttr-128421	Tursiops truncatus	82.21	0.00e+00	1280.00
IUUC-Vpa-130602	Vicugna pacos	82.04	0.00e+00	1445.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence