iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089592

Ensembl Protein ID

ENSOARP00000015820.1

UniProt Accession

W5PZD4; W5PZD4_SHEEP

Genbank Protein ID

ENSOARP00000015820

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01051101

Gene Name

TOPORS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000014752.1	ENSOART00000016053.1	ENSOARP00000015820.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.80e-09	37.1	103	142

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 103  CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 142
           **********999999*************......**********7 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

QGSQQPPGSP LSREEGEAPP PTPAPEGRRR SRRVRLRGSC RHRPSLLGRR LAAAAAHLWI 60
RAGNFEIMAS AAKEFKMDNF SPKAGTSKLQ QTVPADASPD SKCPICLDRF DNVSYLDRCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGGTCGC AGCAACCGCC GGGGTCTCCG CTGTCTCGCG AGGAGGGTGA AGCGCCCCCG 60
CCTACTCCCG CTCCGGAGGG CCGGCGGAGA AGTCGTAGAG TTCGCCTTCG TGGATCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	3.00e-09	55.80
IUUC-Aml-002240	Ailuropoda melanoleuca	88.46	0.00e+00	900.00
IUUC-Atr-002964	Amborella trichopoda	29.37	2.00e-12	65.50
IUUC-Apl-003666	Anas platyrhynchos	60.70	5.00e-142	498.00
IUUC-Aca-005305	Anolis carolinensis	62.79	4.00e-148	519.00
IUUC-Aly-005926	Arabidopsis lyrata	36.17	1.00e-10	60.50
IUUC-Ath-007668	Arabidopsis thaliana	40.00	8.00e-08	50.80
IUUC-Ame-011109	Astyanax mexicanus	52.81	1.00e-112	400.00
IUUC-Bta-012637	Bos taurus	96.67	0.00e+00	949.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	2.00e-11	62.80
IUUC-Bol-015307	Brassica oleracea	32.98	4.00e-10	58.20
IUUC-Bra-017073	Brassica rapa	44.90	2.00e-08	52.00
IUUC-Cja-019105	Callithrix jacchus	90.65	0.00e+00	939.00
IUUC-Cfa-021203	Canis familiaris	88.44	0.00e+00	897.00
IUUC-Cpo-022335	Cavia porcellus	85.52	0.00e+00	816.00
IUUC-Csa-023870	Chlorocebus sabaeus	90.65	0.00e+00	937.00
IUUC-Cho-024870	Choloepus hoffmanni	90.11	0.00e+00	862.00
IUUC-Cne-026788	Cryptococcus neoformans	33.85	4.00e-07	50.10
IUUC-Dre-027535	Danio rerio	52.13	1.00e-119	424.00
IUUC-Dno-028963	Dasypus novemcinctus	89.46	0.00e+00	854.00
IUUC-Dor-030239	Dipodomys ordii	89.53	0.00e+00	782.00
IUUC-Dme-031941	Drosophila melanogaster	32.64	2.00e-38	154.00
IUUC-Ete-032300	Echinops telfairi	82.66	0.00e+00	1097.00
IUUC-Eca-033690	Equus caballus	92.56	0.00e+00	895.00
IUUC-Eeu-035257	Erinaceus europaeus	85.19	0.00e+00	870.00
IUUC-Fca-036383	Felis catus	88.80	0.00e+00	904.00
IUUC-Fal-037209	Ficedula albicollis	69.65	4.00e-157	548.00
IUUC-Gmo-039416	Gadus morhua	53.59	8.00e-118	417.00
IUUC-Gga-041267	Gallus gallus	73.09	3.00e-172	599.00
IUUC-Gac-042227	Gasterosteus aculeatus	52.66	2.00e-115	409.00
IUUC-Gma-042777	Glycine max	32.61	4.00e-09	55.10
IUUC-Ggo-044445	Gorilla gorilla	90.65	0.00e+00	933.00
IUUC-Hsa-045844	Homo sapiens	90.82	0.00e+00	934.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	1.00e-10	57.80
IUUC-Itr-048818	Ictidomys tridecemlineatus	90.46	0.00e+00	932.00
IUUC-Lch-050031	Latimeria chalumnae	67.94	3.00e-167	582.00
IUUC-Lpe-051274	Leersia perrieri	37.74	1.00e-08	53.50
IUUC-Loc-052944	Lepisosteus oculatus	58.67	2.00e-143	503.00
IUUC-Laf-053820	Loxodonta africana	89.91	0.00e+00	853.00
IUUC-Mcc-054800	Macaca mulatta	90.66	0.00e+00	938.00
IUUC-Meu-056806	Macropus eugenii	73.04	0.00e+00	645.00
IUUC-Mtr-058378	Medicago truncatula	34.58	1.00e-12	67.00
IUUC-Mla-059017	Melampsora laricipopulina	36.07	4.00e-09	55.80
IUUC-Mvi-060417	Microbotryum violaceum	24.82	1.00e-17	85.10
IUUC-Mmr-061481	Microcebus murinus	89.97	0.00e+00	899.00
IUUC-Mdo-062219	Monodelphis domestica	82.66	9.00e-111	394.00
IUUC-Mmu-064138	Mus musculus	85.79	0.00e+00	794.00
IUUC-Mlu-067088	Myotis lucifugus	89.97	0.00e+00	901.00
IUUC-Nle-069862	Nomascus leucogenys	90.89	0.00e+00	951.00
IUUC-Opr-071076	Ochotona princeps	88.61	0.00e+00	799.00
IUUC-Ont-072225	Oreochromis niloticus	52.38	2.00e-112	400.00
IUUC-Oan-073069	Ornithorhynchus anatinus	66.98	1.00e-157	549.00
IUUC-Ocu-074826	Oryctolagus cuniculus	89.30	0.00e+00	913.00
IUUC-Oba-075429	Oryza barthii	37.68	1.00e-10	60.10
IUUC-Obr-076084	Oryza brachyantha	36.23	4.00e-10	58.20
IUUC-Ogl-077444	Oryza glaberrima	37.68	2.00e-10	59.70
IUUC-Ogu-078603	Oryza glumaepatula	37.68	1.00e-10	60.10
IUUC-Oin-079777	Oryza indica	37.68	2.00e-10	59.70
IUUC-Oni-082396	Oryza nivara	37.68	1.00e-10	60.10
IUUC-Opu-083698	Oryza punctata	36.62	7.00e-10	57.80
IUUC-Oru-084305	Oryza rufipogon	37.68	2.00e-10	60.10
IUUC-Ola-087377	Oryzias latipes	54.00	5.00e-110	390.00
IUUC-Oga-088059	Otolemur garnettii	88.10	0.00e+00	887.00
IUUC-Ptr-091233	Pan troglodytes	90.65	0.00e+00	932.00
IUUC-Pan-092743	Papio anubis	90.82	0.00e+00	939.00
IUUC-Psi-093669	Pelodiscus sinensis	59.90	0.00e+00	832.00
IUUC-Ppa-095668	Physcomitrella patens	26.43	1.00e-22	101.00
IUUC-Pfo-096706	Poecilia formosa	51.85	3.00e-105	375.00
IUUC-Pop-099119	Populus trichocarpa	35.29	3.00e-08	52.00
IUUC-Pca-100967	Procavia capensis	87.68	0.00e+00	796.00
IUUC-Ppe-101922	Prunus persica	35.06	9.00e-09	53.90
IUUC-Pva-102982	Pteropus vampyrus	91.82	0.00e+00	922.00
IUUC-Pgr-103551	Puccinia graminis	34.25	8.00e-09	54.30
IUUC-Ptt-103977	Puccinia triticina	33.33	7.00e-08	50.80
IUUC-Rno-105730	Rattus norvegicus	84.63	0.00e+00	770.00
IUUC-Sha-106588	Sarcophilus harrisii	74.78	0.00e+00	637.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.38	2.00e-07	49.30
IUUC-Smo-109039	Selaginella moellendorffii	24.16	6.00e-19	88.60
IUUC-Sly-111835	Solanum lycopersicum	42.37	1.00e-08	55.50
IUUC-Stu-112898	Solanum tuberosum	42.37	2.00e-08	55.10
IUUC-Sar-113622	Sorex araneus	90.36	1.00e-163	570.00
IUUC-Sre-115041	Sporisorium reilianum	37.84	1.00e-09	57.00
IUUC-Ssc-115244	Sus scrofa	91.86	0.00e+00	878.00
IUUC-Tgu-117180	Taeniopygia guttata	64.01	9.00e-166	577.00
IUUC-Tru-118393	Takifugu rubripes	54.23	4.00e-120	425.00
IUUC-Tsy-119408	Tarsius syrichta	90.78	0.00e+00	892.00
IUUC-Tni-120664	Tetraodon nigroviridis	56.03	3.00e-120	426.00
IUUC-Tca-121712	Theobroma cacao	27.53	3.00e-17	82.00
IUUC-Tae-122787	Triticum aestivum	38.57	1.00e-10	60.10
IUUC-Tbe-127301	Tupaia belangeri	81.46	0.00e+00	784.00
IUUC-Ttr-128204	Tursiops truncatus	91.68	0.00e+00	927.00
IUUC-Uma-129420	Ustilago maydis	43.06	1.00e-09	57.40
IUUC-Vpa-130297	Vicugna pacos	93.07	0.00e+00	909.00
IUUC-Vvi-131157	Vitis vinifera	25.25	5.00e-17	81.60
IUUC-Xtr-132845	Xenopus tropicalis	67.28	4.00e-170	592.00
IUUC-Xma-133439	Xiphophorus maculatus	53.29	5.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence