iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027652

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

DDB1- and CUL4-associated factor 10; WD repeat-containing protein 32

Genbank Nucleotide ID

BC067591

Gene Name

wdr32; dcaf10; zgc:85718

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000029600.5	ENSDART00000047740.5	ENSDARP00000047739.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-13	50.2	170	202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtg 33
           H+d v+ ++f +++l++++sdD ti +WDlr+ 
   Q: 170  HEDCVNNIRFlDNRLFATCSDDTTIALWDLRKL 202
           9*********7669***************9875 PP

Organism

Danio rerio

Functional Description
(View)

May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Protein Sequence
(Fasta)

MSSGHPSDNE EPRADLLREE EEEEEEEEDS DEDRGSTRPA SPQATRECAG TQGSSRPEVT 60
ADGGTGSASG SGCRGSGACD SLFSWICRRK IRRGPYVDPA RDHFRTMTRL YSSMSPAADS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGCACATC CGCAGTACTG TTGTGTTTGT ATTAATGGAT GTTTAAGCGG TTTCTGCACA 60
CATTGCAGGA CGGCCTGGCT CACGGGTCCA GCGCCTGTGC CTCCACCGCA GGCTGGACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

dre:405882

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002004	Ailuropoda melanoleuca	79.76	0.00e+00	662.00
IUUC-Apl-003942	Anas platyrhynchos	77.19	2.00e-176	612.00
IUUC-Aca-005259	Anolis carolinensis	76.92	0.00e+00	671.00
IUUC-Ame-010936	Astyanax mexicanus	84.54	0.00e+00	837.00
IUUC-Bta-012820	Bos taurus	77.46	0.00e+00	694.00
IUUC-Cja-019380	Callithrix jacchus	77.80	0.00e+00	679.00
IUUC-Cfa-021136	Canis familiaris	78.26	0.00e+00	688.00
IUUC-Cpo-021784	Cavia porcellus	78.52	0.00e+00	689.00
IUUC-Csa-024250	Chlorocebus sabaeus	77.28	0.00e+00	679.00
IUUC-Cin-025712	Ciona intestinalis	43.11	9.00e-37	146.00
IUUC-Csv-025985	Ciona savignyi	38.01	4.00e-34	138.00
IUUC-Dno-030060	Dasypus novemcinctus	80.05	5.00e-178	616.00
IUUC-Dme-031950	Drosophila melanogaster	38.59	1.00e-49	191.00
IUUC-Ete-032379	Echinops telfairi	67.80	6.00e-136	477.00
IUUC-Eca-034313	Equus caballus	80.47	5.00e-177	613.00
IUUC-Fca-036273	Felis catus	78.67	0.00e+00	694.00
IUUC-Fal-037620	Ficedula albicollis	79.69	1.00e-176	612.00
IUUC-Gmo-038647	Gadus morhua	84.24	0.00e+00	638.00
IUUC-Gga-040735	Gallus gallus	79.47	2.00e-175	608.00
IUUC-Gac-041703	Gasterosteus aculeatus	88.48	0.00e+00	776.00
IUUC-Ggo-045268	Gorilla gorilla	78.44	0.00e+00	674.00
IUUC-Hsa-046127	Homo sapiens	78.44	0.00e+00	676.00
IUUC-Itr-048027	Ictidomys tridecemlineatus	78.78	2.00e-156	544.00
IUUC-Lch-050191	Latimeria chalumnae	79.22	0.00e+00	692.00
IUUC-Loc-052006	Lepisosteus oculatus	83.33	0.00e+00	734.00
IUUC-Laf-053546	Loxodonta africana	78.25	0.00e+00	696.00
IUUC-Mcc-055391	Macaca mulatta	79.47	1.00e-172	598.00
IUUC-Meu-056599	Macropus eugenii	84.00	1.00e-87	317.00
IUUC-Mga-059625	Meleagris gallopavo	90.53	6.00e-89	320.00
IUUC-Mmr-061695	Microcebus murinus	79.15	0.00e+00	690.00
IUUC-Mdo-062960	Monodelphis domestica	80.00	0.00e+00	702.00
IUUC-Mmu-063543	Mus musculus	79.59	0.00e+00	689.00
IUUC-Mpu-066132	Mustela putorius furo	78.49	0.00e+00	681.00
IUUC-Mlu-067070	Myotis lucifugus	78.74	6.00e-173	600.00
IUUC-Nle-069325	Nomascus leucogenys	79.47	1.00e-172	599.00
IUUC-Opr-070537	Ochotona princeps	92.36	4.00e-77	282.00
IUUC-Ont-072184	Oreochromis niloticus	89.53	0.00e+00	788.00
IUUC-Oan-072696	Ornithorhynchus anatinus	76.81	3.00e-178	618.00
IUUC-Ocu-074877	Oryctolagus cuniculus	78.44	0.00e+00	700.00
IUUC-Ola-086632	Oryzias latipes	84.68	0.00e+00	666.00
IUUC-Oga-088050	Otolemur garnettii	78.25	0.00e+00	686.00
IUUC-Oar-089358	Ovis aries	70.76	3.00e-180	625.00
IUUC-Ptr-091497	Pan troglodytes	78.44	0.00e+00	677.00
IUUC-Pan-092813	Papio anubis	77.56	0.00e+00	689.00
IUUC-Psi-093404	Pelodiscus sinensis	79.74	2.00e-176	611.00
IUUC-Pfo-097103	Poecilia formosa	87.91	0.00e+00	782.00
IUUC-Pab-098099	Pongo abelii	77.80	0.00e+00	680.00
IUUC-Pca-100777	Procavia capensis	76.70	5.00e-39	155.00
IUUC-Pva-102912	Pteropus vampyrus	77.85	0.00e+00	692.00
IUUC-Rno-104970	Rattus norvegicus	79.15	0.00e+00	691.00
IUUC-Sha-106821	Sarcophilus harrisii	80.00	0.00e+00	692.00
IUUC-Sar-113508	Sorex araneus	83.43	5.00e-88	317.00
IUUC-Ssc-116373	Sus scrofa	78.64	0.00e+00	686.00
IUUC-Tgu-117223	Taeniopygia guttata	80.00	4.00e-176	610.00
IUUC-Tru-118116	Takifugu rubripes	55.94	6.00e-127	447.00
IUUC-Tsy-119525	Tarsius syrichta	80.05	1.00e-174	605.00
IUUC-Tni-119799	Tetraodon nigroviridis	85.58	0.00e+00	757.00
IUUC-Ttr-128611	Tursiops truncatus	73.88	0.00e+00	652.00
IUUC-Vpa-130806	Vicugna pacos	83.43	2.00e-87	316.00
IUUC-Xtr-132913	Xenopus tropicalis	78.20	0.00e+00	691.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence