iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062462

UUCD1 version

UUC-MoD-00359

Ensembl Protein ID

ENSMODP00000002182.1

UniProt Accession

F6WIY1; F6WIY1_MONDO

Protein Name

Uncharacterized protein

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001783.3	ENSMODT00000002227.1	ENSMODP00000002182.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-56	186.1	42	80
UBD/Beta-Prp	2.70e-130	434.1	4	202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           Ht ++ claf sd  +l+s + D  +t+ +WD+++g+ll
   Q: 42   HTHGIACLAFdSDgQRLASVGLDakNTVCIWDWKKGKLL 80
           99*********999*******9999**********9987 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkghedsvls 99
           ++ +pdk+l+atg  ++d  i +wd  + ++++ l   h+ +++++ f++dg+ l++++ D  +t+++wd ++gk + t +gh+d++ +
   Q: 4    LALHPDKTLVATGqvGKDPYICIWDSYNVQTVSILkDVHTHGIACLAFDSDGQRLASVGLDakNTVCIWDWKKGKLLATATGHSDRIFD 92
           5679********95558999***************777*************************************************** PP
   S: 100  lsfspsg.dklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +s++p++ +++vs   ++ i+ w l  +    +  ++ ++ ++ +++++ + + ++  sG+l++ + +W+    +l+rt +g+h   + 
   Q: 93   ISWDPYQpNRVVSC-GVKHIKFWTLCGNALTAKrgIFGKTGDLQTILCLACAKeDVTYSGALNGDIYVWKG--LNLVRTIQGAHSAGIF 178
           *****994555555.5*******99999999889966666666666666666669999***********66..99************** PP
   S: 185  slsfdsngkelvsgsldgtvklwdlq 210
           s+   ++g  +++g++dg ++lwd+ 
   Q: 179  SMYACDEG--FATGGRDGCIRLWDID 202
           ***99965..**************97 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

FFSLALHPDK TLVATGQVGK DPYICIWDSY NVQTVSILKD VHTHGIACLA FDSDGQRLAS 60
VGLDAKNTVC IWDWKKGKLL ATATGHSDRI FDISWDPYQP NRVVSCGVKH IKFWTLCGNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTCAGCC TTGCCTTACA CCCAGATAAA ACCCTGGTTG CTACTGGACA AGTTGGAAAA 60
GATCCTTATA TTTGCATTTG GGATTCTTAT AATGTACAGA CCGTTTCTAT TCTTAAAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	95.41	0.00e+00	3675.00
IUUC-Apl-003604	Anas platyrhynchos	94.17	0.00e+00	3597.00
IUUC-Aca-004572	Anolis carolinensis	90.05	0.00e+00	3488.00
IUUC-Ame-010713	Astyanax mexicanus	80.52	0.00e+00	3087.00
IUUC-Bta-012812	Bos taurus	95.36	0.00e+00	3671.00
IUUC-Cja-019191	Callithrix jacchus	95.15	0.00e+00	3669.00
IUUC-Cfa-020041	Canis familiaris	96.04	0.00e+00	3422.00
IUUC-Csa-023689	Chlorocebus sabaeus	94.67	0.00e+00	3652.00
IUUC-Cho-025038	Choloepus hoffmanni	94.65	0.00e+00	1453.00
IUUC-Cin-025205	Ciona intestinalis	62.03	0.00e+00	2465.00
IUUC-Csv-026014	Ciona savignyi	63.18	0.00e+00	2476.00
IUUC-Dno-029982	Dasypus novemcinctus	93.92	0.00e+00	3609.00
IUUC-Eca-034161	Equus caballus	94.26	0.00e+00	3617.00
IUUC-Fca-036307	Felis catus	95.73	0.00e+00	3677.00
IUUC-Fal-037332	Ficedula albicollis	92.50	0.00e+00	3539.00
IUUC-Gmo-039057	Gadus morhua	74.10	0.00e+00	2847.00
IUUC-Gac-042555	Gasterosteus aculeatus	79.69	0.00e+00	3114.00
IUUC-Ggo-045107	Gorilla gorilla	95.57	0.00e+00	3677.00
IUUC-Hsa-046482	Homo sapiens	95.62	0.00e+00	3676.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	94.06	0.00e+00	3658.00
IUUC-Loc-052642	Lepisosteus oculatus	88.01	0.00e+00	3372.00
IUUC-Laf-053649	Loxodonta africana	94.88	0.00e+00	3606.00
IUUC-Mcc-055361	Macaca mulatta	95.34	0.00e+00	3307.00
IUUC-Meu-056618	Macropus eugenii	80.37	0.00e+00	1741.00
IUUC-Mga-059202	Meleagris gallopavo	93.20	0.00e+00	3588.00
IUUC-Mmr-060729	Microcebus murinus	95.10	0.00e+00	3657.00
IUUC-Mmu-063865	Mus musculus	94.51	0.00e+00	3660.00
IUUC-Mpu-066724	Mustela putorius furo	96.09	0.00e+00	3691.00
IUUC-Mlu-067816	Myotis lucifugus	95.48	0.00e+00	3682.00
IUUC-Opr-070213	Ochotona princeps	92.01	0.00e+00	1958.00
IUUC-Ont-071928	Oreochromis niloticus	79.18	0.00e+00	3137.00
IUUC-Oan-073563	Ornithorhynchus anatinus	95.32	0.00e+00	3655.00
IUUC-Ocu-074531	Oryctolagus cuniculus	95.30	0.00e+00	3669.00
IUUC-Ola-086943	Oryzias latipes	78.75	0.00e+00	3137.00
IUUC-Olu-087860	Ostreococcus lucimarinus	39.01	6.00e-118	418.00
IUUC-Oga-088665	Otolemur garnettii	94.59	0.00e+00	3635.00
IUUC-Oar-090429	Ovis aries	95.46	0.00e+00	3677.00
IUUC-Ptr-091168	Pan troglodytes	91.75	0.00e+00	3083.00
IUUC-Pan-092788	Papio anubis	95.32	0.00e+00	2998.00
IUUC-Psi-093281	Pelodiscus sinensis	92.59	0.00e+00	3529.00
IUUC-Pma-094424	Petromyzon marinus	71.74	2.00e-122	431.00
IUUC-Pfo-096150	Poecilia formosa	79.46	0.00e+00	2971.00
IUUC-Pab-098561	Pongo abelii	94.55	0.00e+00	3170.00
IUUC-Pca-100107	Procavia capensis	61.37	0.00e+00	1953.00
IUUC-Rno-105002	Rattus norvegicus	93.56	0.00e+00	3647.00
IUUC-Sha-107105	Sarcophilus harrisii	96.21	0.00e+00	3645.00
IUUC-Ssc-116282	Sus scrofa	95.88	0.00e+00	3691.00
IUUC-Tgu-116807	Taeniopygia guttata	93.88	0.00e+00	3586.00
IUUC-Tru-118040	Takifugu rubripes	78.33	0.00e+00	3056.00
IUUC-Tni-120118	Tetraodon nigroviridis	75.72	0.00e+00	3029.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence