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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Ath-006676
Ensembl Protein ID AT3G02540.1
UniProt Accession Q84L31; Q9M887; RD23C_ARATH
Genbank Protein ID BAC76392.1; BAC76393.1; AAF32461.1; AEE73824.1; AAK62617.1; AAM47342.1
Protein Name Ubiquitin receptor RAD23c; Putative DNA repair protein RAD23-3; RAD23-like protein 3
Genbank Nucleotide ID AB109196; AB109197; AC021640; CP002686; AY039562; AY113034
Gene Name RAD23C; RAD23; RAD23-3; At3g02540; F16B3.17
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT3G02540 AT3G02540.2 AT3G02540.2
AT3G02540 AT3G02540.1 AT3G02540.1
AT3G02540 AT3G02540.3 AT3G02540.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
PINAHINTMentha
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UBA UBA 20059542; 20086187; 21764993
ULD/UDP/UFD/MUB MUB 20086187; 25320573
Classification
Family E-value Score Start End
UBD/Alpha-Helix/UBA 6.10e-23 81.1 187 228
ULD/UDP/UBQ/UBQ_PIM 2.60e-25 89.0 1 78
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBA
   S: 3    dedkleqlveMG...FdreealqaLraannnleaAveyLldg 41
           +e+ ++q+ +MG   +dre+++ aLraa+nn+e+AveyL++g
   Q: 187  LESTIQQILDMGggtWDRETVVLALRAAFNNPERAVEYLYTG 228
           799*************************************87 PP
   

   ULD/UDP/UBQ/UBQ_PIM
   S: 1    mkltvktlkgkefelevseddtveelKekiakesg...vppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk++vktlkg++fe+ev+++d+v ++K++i++++g   +p+++q LI++Gk+LkD+tt++e+++ ++s+++++++ksk
   Q: 1    MKIFVKTLKGTHFEIEVKPEDSVVDVKKNIESVQGadvYPAAKQMLIHQGKVLKDETTIEENKVAENSFIVIMMNKSK 78
           99************************************************************************9997 PP
   
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP).
 May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP).
Protein Sequence
(Fasta)
MKIFVKTLKG THFEIEVKPE DSVVDVKKNI ESVQGADVYP AAKQMLIHQG KVLKDETTIE 60
ENKVAENSFI VIMMNKSKPA SAAASSASAG TSQAKSIPPS TSQPSISPQT PASVSAPVAP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-006676|UBD,UBA;ULD,MUB;ULD,UBQ_PIM|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTAAGGAAAT TGTCAATACC ACGTGGCATA TTTTAATAGG ATAATGGCGG CTGACCTGGC 60
AGAGTTGAAA GCACAAGCCA TGTGCTTCGG GTGTGATCCA GTGGAGATAT CGAGGGAACG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-006676|UBD,UBA;ULD,MUB;ULD,UBQ_PIM|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0234--DNA repair
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR004806--Rad23
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR015360--XPC-bd
PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2
Pfam

PF00627--UBA
PF00240--ubiquitin
PF09280--XPC-binding
PRINTS

PR01839--RAD23PROTEIN
SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0031593--F:polyubiquitin binding
GO:0070628--F:proteasome binding
GO:0043130--F:ubiquitin binding
GO:0006289--P:nucleotide-excision repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
KEGG ath:AT3G02540
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001195 Ailuropoda melanoleuca 39.62 4.00e-31 128.00
IUUC-Atr-003116 Amborella trichopoda 78.49 2.00e-98 352.00
IUUC-Apl-003371 Anas platyrhynchos 38.70 1.00e-34 139.00
IUUC-Aca-004599 Anolis carolinensis 39.45 2.00e-29 122.00
IUUC-Aly-005498 Arabidopsis lyrata 97.60 2.00e-127 448.00
IUUC-Ame-011107 Astyanax mexicanus 42.21 1.00e-28 120.00
IUUC-Bgr-012056 Blumeria graminis 31.31 1.00e-31 129.00
IUUC-Bdi-014253 Brachypodium distachyon 66.80 2.00e-84 305.00
IUUC-Bol-015641 Brassica oleracea 76.94 4.00e-140 490.00
IUUC-Bra-017983 Brassica rapa 77.14 2.00e-149 521.00
IUUC-Cfa-020683 Canis familiaris 38.97 5.00e-30 124.00
IUUC-Cpo-022145 Cavia porcellus 40.98 1.00e-35 143.00
IUUC-Cre-022810 Chlamydomonas reinhardtii 35.34 2.00e-22 99.40
IUUC-Csa-023714 Chlorocebus sabaeus 38.32 6.00e-34 137.00
IUUC-Ete-032583 Echinops telfairi 40.00 7.00e-21 94.40
IUUC-Eeu-034721 Erinaceus europaeus 40.00 9.00e-21 93.60
IUUC-Gac-042298 Gasterosteus aculeatus 35.75 3.00e-42 164.00
IUUC-Gma-043937 Glycine max 80.88 7.00e-111 393.00
IUUC-Ggo-045125 Gorilla gorilla 38.55 5.00e-33 134.00
IUUC-Hsa-046519 Homo sapiens 38.55 5.00e-33 134.00
IUUC-Lch-050553 Latimeria chalumnae 41.98 2.00e-29 122.00
IUUC-Laf-054293 Loxodonta africana 39.68 5.00e-32 131.00
IUUC-Mcc-055600 Macaca mulatta 38.32 2.00e-33 135.00
IUUC-Mmr-061159 Microcebus murinus 39.44 1.00e-32 133.00
IUUC-Mmu-063258 Mus musculus 39.11 3.00e-36 145.00
IUUC-Mac-064724 Musa acuminata 63.51 3.00e-132 464.00
IUUC-Nle-069655 Nomascus leucogenys 38.32 9.00e-34 137.00
IUUC-Ont-072484 Oreochromis niloticus 36.34 2.00e-52 199.00
IUUC-Olo-081091 Oryza longistaminata 63.41 7.00e-85 307.00
IUUC-Ptr-091165 Pan troglodytes 38.55 8.00e-33 133.00
IUUC-Pan-092009 Papio anubis 38.27 2.00e-32 132.00
IUUC-Psi-093477 Pelodiscus sinensis 40.89 2.00e-28 119.00
IUUC-Pgr-103618 Puccinia graminis 39.78 9.00e-29 120.00
IUUC-Ptt-103717 Puccinia triticina 47.45 1.00e-26 113.00
IUUC-Rno-104844 Rattus norvegicus 39.26 1.00e-35 143.00
IUUC-Sha-107073 Sarcophilus harrisii 39.75 2.00e-30 125.00
IUUC-Sly-111609 Solanum lycopersicum 75.70 5.00e-98 350.00
IUUC-Stu-112027 Solanum tuberosum 65.58 1.00e-145 508.00
IUUC-Sar-112925 Sorex araneus 40.34 9.00e-29 120.00
IUUC-Sre-114894 Sporisorium reilianum 55.00 2.00e-12 66.60
IUUC-Tgu-116918 Taeniopygia guttata 38.95 4.00e-34 138.00
IUUC-Tru-117920 Takifugu rubripes 42.28 8.00e-44 170.00
IUUC-Tni-120493 Tetraodon nigroviridis 44.05 5.00e-43 167.00
IUUC-Vvi-130842 Vitis vinifera 84.13 8.00e-109 386.00
IUUC-Xtr-132679 Xenopus tropicalis 38.66 2.00e-23 102.00
Created Date 25-Jun-2017

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