iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098241

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

ABGA01103131

Gene Name

KMT2C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000018200.2	ENSPPYT00000021212.2	ENSPPYP00000020408.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.20e-28	96.6	1032	1083

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
           +C+vC +++++e+ +++C++C++w+H+ C +l+ eee++n  +  + C+ Cr
   Q: 1032 SCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADigFDCSMCR 1083
           6********************************999999998899******8 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

PRSRGKTAVE DEDSMDGLET TETETIVETE IKEQSAEEDA EAEVDNSKLL IPTLQRSVSE 60
ESANSLVSVG VEAKISEQLC AFCYCGEKSS LGQGDLKQFR VTPGFILPWR NQPSNKKDID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNTGTGTG TTTTTTGCGT GTCCTGCTCG CTCCATGTTG CCGCCTCTCC 60
CGGTACCTGC TGCTGCTCCC GGGGCTGCGG GAAATGCGAG AGGCTGAGCC GGGGAGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	87.97	0.00e+00	4650.00
IUUC-Apl-003311	Anas platyrhynchos	72.44	0.00e+00	3632.00
IUUC-Aca-004705	Anolis carolinensis	64.83	0.00e+00	3263.00
IUUC-Bta-012322	Bos taurus	82.26	0.00e+00	4246.00
IUUC-Cel-018354	Caenorhabditis elegans	35.38	1.00e-64	243.00
IUUC-Cja-019983	Callithrix jacchus	95.69	0.00e+00	5257.00
IUUC-Cfa-020903	Canis familiaris	87.87	0.00e+00	4827.00
IUUC-Cpo-021732	Cavia porcellus	80.91	0.00e+00	4414.00
IUUC-Csa-023083	Chlorocebus sabaeus	96.96	0.00e+00	3464.00
IUUC-Cho-024469	Choloepus hoffmanni	83.33	0.00e+00	1799.00
IUUC-Dre-028110	Danio rerio	63.45	0.00e+00	1214.00
IUUC-Dor-030569	Dipodomys ordii	80.53	0.00e+00	4160.00
IUUC-Dme-031590	Drosophila melanogaster	33.01	1.00e-67	251.00
IUUC-Eca-033945	Equus caballus	87.23	0.00e+00	2633.00
IUUC-Fca-035922	Felis catus	84.53	0.00e+00	4372.00
IUUC-Gmo-039403	Gadus morhua	62.93	0.00e+00	728.00
IUUC-Gac-041896	Gasterosteus aculeatus	52.78	0.00e+00	1226.00
IUUC-Ggo-044812	Gorilla gorilla	96.86	0.00e+00	5412.00
IUUC-Hsa-046595	Homo sapiens	97.73	0.00e+00	5402.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	86.40	0.00e+00	4516.00
IUUC-Lch-050086	Latimeria chalumnae	67.49	0.00e+00	2063.00
IUUC-Loc-052891	Lepisosteus oculatus	75.07	0.00e+00	1495.00
IUUC-Laf-054348	Loxodonta africana	83.94	0.00e+00	1992.00
IUUC-Mcc-054868	Macaca mulatta	97.27	0.00e+00	5321.00
IUUC-Meu-056322	Macropus eugenii	67.80	0.00e+00	1211.00
IUUC-Mga-059541	Meleagris gallopavo	71.17	0.00e+00	3498.00
IUUC-Mmr-061092	Microcebus murinus	87.69	0.00e+00	3089.00
IUUC-Mdo-062610	Monodelphis domestica	76.74	0.00e+00	2075.00
IUUC-Mmu-063666	Mus musculus	84.37	0.00e+00	4426.00
IUUC-Mpu-066366	Mustela putorius furo	84.83	0.00e+00	4443.00
IUUC-Mlu-068201	Myotis lucifugus	84.58	0.00e+00	2530.00
IUUC-Nle-069232	Nomascus leucogenys	97.46	0.00e+00	3514.00
IUUC-Opr-070625	Ochotona princeps	77.29	0.00e+00	1341.00
IUUC-Ont-072401	Oreochromis niloticus	55.96	0.00e+00	1016.00
IUUC-Oan-072945	Ornithorhynchus anatinus	69.99	0.00e+00	2029.00
IUUC-Ocu-074920	Oryctolagus cuniculus	83.45	0.00e+00	2855.00
IUUC-Ola-086436	Oryzias latipes	50.00	0.00e+00	1207.00
IUUC-Oga-088637	Otolemur garnettii	85.37	0.00e+00	2854.00
IUUC-Oar-089363	Ovis aries	79.98	0.00e+00	4072.00
IUUC-Ptr-091527	Pan troglodytes	97.80	0.00e+00	5461.00
IUUC-Pan-092102	Papio anubis	95.19	0.00e+00	5168.00
IUUC-Pfo-096288	Poecilia formosa	60.29	0.00e+00	1129.00
IUUC-Pca-100103	Procavia capensis	81.58	0.00e+00	1593.00
IUUC-Pva-102238	Pteropus vampyrus	78.82	0.00e+00	1909.00
IUUC-Rno-105395	Rattus norvegicus	75.84	0.00e+00	1115.00
IUUC-Sha-106550	Sarcophilus harrisii	70.72	0.00e+00	2143.00
IUUC-Smo-109624	Selaginella moellendorffii	32.37	9.00e-22	99.00
IUUC-Sly-111442	Solanum lycopersicum	33.33	2.00e-24	107.00
IUUC-Sar-113183	Sorex araneus	90.68	2.00e-156	548.00
IUUC-Tgu-116677	Taeniopygia guttata	71.40	0.00e+00	3555.00
IUUC-Tru-118037	Takifugu rubripes	53.36	0.00e+00	1242.00
IUUC-Tsy-118932	Tarsius syrichta	91.10	0.00e+00	4881.00
IUUC-Tni-119970	Tetraodon nigroviridis	52.79	0.00e+00	1260.00
IUUC-Ttr-129051	Tursiops truncatus	85.05	0.00e+00	4059.00
IUUC-Vda-129876	Verticillium dahliae	52.08	1.00e-08	55.10
IUUC-Vpa-130236	Vicugna pacos	83.56	0.00e+00	1989.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence