iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.50e-07	29.3	1461	1480

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 14   tllvsGsdDgtikvWDlrtg 33
           + +++G+dDg+++++D r+ 
   Q: 1461 DVILAGCDDGSVRLFDKRCA 1480
           569*************8876 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MTSAVRAKSA AAAVGVAVDE SSGSSNGSVA DQEVASSKEA VLSVLIRKRY EKYVFAPWDD 60
PIILIMEQLE HIEHCRSAAL GNQVAIGRDP SQDDSLNDLG KVISNMRQDQ SLVPIVKHIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCAATTCTT TTCGTATAAT ATAATTCGAT TAAACATAAA TAAATAAACC CAAGCGAAAG 60
TAAATAAACC TGTTAATGCG CACCATCTTC CGTCGGAGAT CGCTCGCTAT AGTTGTACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR029030--Caspase-like_dom
IPR000357--HEAT
IPR004083--Raptor
IPR029347--Raptor_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

Pfam

PF02985--HEAT
PF14538--Raptor_N

SMART

SM01302--Raptor_N
SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0031931--C:TORC1 complex
GO:0030674--F:protein binding, bridging
GO:0006914--P:autophagy
GO:0007411--P:axon guidance
GO:0071230--P:cellular response to amino acid stimulus
GO:0006974--P:cellular response to DNA damage stimulus
GO:0009267--P:cellular response to starvation
GO:0008340--P:determination of adult lifespan
GO:0007562--P:eclosion
GO:0035096--P:larval midgut cell programmed cell death
GO:0007517--P:muscle organ development
GO:0045886--P:negative regulation of synaptic growth at neuromuscular junction
GO:0048477--P:oogenesis
GO:0030307--P:positive regulation of cell growth
GO:0040018--P:positive regulation of multicellular organism growth
GO:0001934--P:positive regulation of protein phosphorylation
GO:0071902--P:positive regulation of protein serine/threonine kinase activity
GO:0010506--P:regulation of autophagy
GO:0008361--P:regulation of cell size
GO:0031929--P:TOR signaling

KEGG

dme:Dmel_CG4320

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000354	Aegilops tauschii	43.68	1.00e-168	587.00
IUUC-Aml-001499	Ailuropoda melanoleuca	64.71	0.00e+00	899.00
IUUC-Atr-002704	Amborella trichopoda	54.98	0.00e+00	655.00
IUUC-Apl-003540	Anas platyrhynchos	65.48	0.00e+00	895.00
IUUC-Aca-004449	Anolis carolinensis	63.73	0.00e+00	750.00
IUUC-Aly-006524	Arabidopsis lyrata	55.02	0.00e+00	701.00
IUUC-Ath-007242	Arabidopsis thaliana	55.18	0.00e+00	701.00
IUUC-Ago-007709	Ashbya gossypii	48.23	3.00e-111	396.00
IUUC-Acl-008215	Aspergillus clavatus	49.36	0.00e+00	668.00
IUUC-Afl-008401	Aspergillus flavus	44.71	0.00e+00	669.00
IUUC-Afu-008797	Aspergillus fumigatus	50.74	0.00e+00	667.00
IUUC-Ani-009268	Aspergillus nidulans	50.07	0.00e+00	659.00
IUUC-Ang-009608	Aspergillus niger	50.22	0.00e+00	647.00
IUUC-Aor-009894	Aspergillus oryzae	44.71	0.00e+00	668.00
IUUC-Ate-010357	Aspergillus terreus	50.22	0.00e+00	667.00
IUUC-Ame-011186	Astyanax mexicanus	63.49	0.00e+00	807.00
IUUC-Bgr-012085	Blumeria graminis	47.45	2.00e-170	593.00
IUUC-Bta-013422	Bos taurus	64.86	0.00e+00	900.00
IUUC-Bci-013736	Botrytis cinerea	47.89	1.00e-174	606.00
IUUC-Bdi-015042	Brachypodium distachyon	44.37	1.00e-176	613.00
IUUC-Bol-016048	Brassica oleracea	56.13	0.00e+00	706.00
IUUC-Bra-016961	Brassica rapa	55.25	0.00e+00	718.00
IUUC-Cel-018321	Caenorhabditis elegans	45.16	3.00e-103	369.00
IUUC-Cja-018939	Callithrix jacchus	64.71	0.00e+00	903.00
IUUC-Cfa-020898	Canis familiaris	64.86	0.00e+00	901.00
IUUC-Cpo-021514	Cavia porcellus	64.71	0.00e+00	904.00
IUUC-Cre-022818	Chlamydomonas reinhardtii	57.42	1.00e-103	368.00
IUUC-Csa-023314	Chlorocebus sabaeus	64.58	0.00e+00	903.00
IUUC-Cin-025701	Ciona intestinalis	61.05	0.00e+00	842.00
IUUC-Csv-026362	Ciona savignyi	59.91	0.00e+00	835.00
IUUC-Cgl-026561	Colletotrichum gloeosporioides	49.34	5.00e-176	611.00
IUUC-Cne-027009	Cryptococcus neoformans	43.07	0.00e+00	627.00
IUUC-Cme-027253	Cyanidioschyzon merolae	50.99	3.00e-124	439.00
IUUC-Dre-028485	Danio rerio	64.83	0.00e+00	910.00
IUUC-Dno-029901	Dasypus novemcinctus	64.41	0.00e+00	772.00
IUUC-Dor-030140	Dipodomys ordii	58.16	0.00e+00	703.00
IUUC-Dse-031462	Dothistroma septosporum	45.78	3.00e-171	595.00
IUUC-Ete-032578	Echinops telfairi	74.85	7.00e-75	275.00
IUUC-Eca-034076	Equus caballus	64.67	0.00e+00	900.00
IUUC-Eeu-035140	Erinaceus europaeus	61.46	0.00e+00	773.00
IUUC-Fca-035651	Felis catus	65.01	0.00e+00	905.00
IUUC-Fal-037244	Ficedula albicollis	64.72	0.00e+00	900.00
IUUC-Fox-037742	Fusarium oxysporum	49.40	4.00e-173	601.00
IUUC-Fso-038369	Fusarium solani	49.35	4.00e-163	568.00
IUUC-Gmo-039007	Gadus morhua	63.51	2.00e-156	545.00
IUUC-Ggr-039836	Gaeumannomyces graminis	48.44	4.00e-176	611.00
IUUC-Gga-041121	Gallus gallus	65.01	0.00e+00	907.00
IUUC-Gac-041430	Gasterosteus aculeatus	64.53	0.00e+00	904.00
IUUC-Gma-043160	Glycine max	55.32	0.00e+00	709.00
IUUC-Ggo-044934	Gorilla gorilla	66.05	0.00e+00	875.00
IUUC-Hsa-045887	Homo sapiens	64.58	0.00e+00	904.00
IUUC-Hvu-047823	Hordeum vulgare	46.45	0.00e+00	664.00
IUUC-Itr-048274	Ictidomys tridecemlineatus	65.90	2.00e-94	338.00
IUUC-Kpa-049399	Komagataella pastoris	51.61	1.00e-111	397.00
IUUC-Lch-050405	Latimeria chalumnae	64.83	0.00e+00	907.00
IUUC-Lpe-050864	Leersia perrieri	56.86	2.00e-141	495.00
IUUC-Loc-051868	Lepisosteus oculatus	61.22	0.00e+00	847.00
IUUC-Lma-052993	Leptosphaeria maculans	49.26	0.00e+00	666.00
IUUC-Laf-053339	Loxodonta africana	64.71	0.00e+00	900.00
IUUC-Mcc-055591	Macaca mulatta	64.58	0.00e+00	903.00
IUUC-Meu-056642	Macropus eugenii	60.44	0.00e+00	663.00
IUUC-Mor-057204	Magnaporthe oryzae	43.01	3.00e-175	608.00
IUUC-Mpo-057532	Magnaporthe poae	48.92	1.00e-175	609.00
IUUC-Mtr-058553	Medicago truncatula	54.10	0.00e+00	697.00
IUUC-Mla-058907	Melampsora laricipopulina	41.00	5.00e-137	481.00
IUUC-Mga-059256	Meleagris gallopavo	64.83	0.00e+00	907.00
IUUC-Mvi-060457	Microbotryum violaceum	47.36	3.00e-180	625.00
IUUC-Mmr-060874	Microcebus murinus	63.12	0.00e+00	850.00
IUUC-Mdo-062436	Monodelphis domestica	65.01	0.00e+00	906.00
IUUC-Mmu-063264	Mus musculus	64.24	0.00e+00	902.00
IUUC-Mac-065524	Musa acuminata	54.78	0.00e+00	659.00
IUUC-Mpu-065899	Mustela putorius furo	64.76	0.00e+00	805.00
IUUC-Mlu-067344	Myotis lucifugus	67.33	7.00e-178	617.00
IUUC-Nfi-068615	Neosartorya fischeri	50.74	0.00e+00	667.00
IUUC-Ncr-068744	Neurospora crassa	45.63	4.00e-166	578.00
IUUC-Nle-069014	Nomascus leucogenys	64.53	0.00e+00	902.00
IUUC-Opr-070548	Ochotona princeps	62.03	2.00e-117	417.00
IUUC-Ont-072485	Oreochromis niloticus	64.68	0.00e+00	908.00
IUUC-Oan-073253	Ornithorhynchus anatinus	26.64	6.00e-20	90.90
IUUC-Oba-075130	Oryza barthii	51.77	0.00e+00	644.00
IUUC-Obr-076161	Oryza brachyantha	53.20	0.00e+00	664.00
IUUC-Ogl-077800	Oryza glaberrima	53.66	0.00e+00	665.00
IUUC-Ogu-078292	Oryza glumaepatula	69.75	1.00e-47	183.00
IUUC-Oin-080126	Oryza indica	48.48	9.00e-163	567.00
IUUC-Olo-080598	Oryza longistaminata	39.32	4.00e-22	99.00
IUUC-Ome-081293	Oryza meridionalis	75.61	6.00e-15	76.30
IUUC-Oni-082236	Oryza nivara	54.18	1.00e-78	287.00
IUUC-Opu-083423	Oryza punctata	53.05	0.00e+00	654.00
IUUC-Oru-085086	Oryza rufipogon	56.79	2.00e-177	616.00
IUUC-Osa-086012	Oryza sativa	53.06	0.00e+00	635.00
IUUC-Ola-086662	Oryzias latipes	62.55	0.00e+00	667.00
IUUC-Olu-087760	Ostreococcus lucimarinus	53.36	0.00e+00	663.00
IUUC-Oga-088053	Otolemur garnettii	64.94	0.00e+00	810.00
IUUC-Oar-089466	Ovis aries	58.02	0.00e+00	813.00
IUUC-Ptr-090868	Pan troglodytes	64.71	0.00e+00	903.00
IUUC-Pan-092259	Papio anubis	64.58	0.00e+00	903.00
IUUC-Psi-093641	Pelodiscus sinensis	63.31	0.00e+00	781.00
IUUC-Pno-094789	Phaeosphaeria nodorum	51.24	2.00e-121	429.00
IUUC-Ppa-095301	Physcomitrella patens	56.32	0.00e+00	689.00
IUUC-Pfo-096837	Poecilia formosa	64.30	0.00e+00	898.00
IUUC-Pab-097545	Pongo abelii	66.28	6.00e-95	340.00
IUUC-Pop-099059	Populus trichocarpa	56.41	0.00e+00	687.00
IUUC-Pca-100579	Procavia capensis	44.66	2.00e-66	247.00
IUUC-Ppe-101494	Prunus persica	54.93	0.00e+00	706.00
IUUC-Pva-103245	Pteropus vampyrus	61.33	1.00e-156	546.00
IUUC-Pgr-103460	Puccinia graminis	43.22	6.00e-43	169.00
IUUC-Ptt-103797	Puccinia triticina	32.54	3.00e-55	210.00
IUUC-Pte-104367	Pyrenophora teres	48.96	0.00e+00	657.00
IUUC-Pyt-104771	Pyrenophora triticirepentis	48.79	9.00e-179	620.00
IUUC-Rno-104965	Rattus norvegicus	64.24	0.00e+00	902.00
IUUC-Sce-106156	Saccharomyces cerevisiae	46.78	8.00e-105	375.00
IUUC-Sha-106474	Sarcophilus harrisii	67.00	6.00e-159	554.00
IUUC-Sja-107888	Schizosaccharomyces japonicus	51.96	0.00e+00	668.00
IUUC-Spo-108057	Schizosaccharomyces pombe	52.53	0.00e+00	660.00
IUUC-Ssl-108423	Sclerotinia sclerotiorum	48.03	2.00e-176	612.00
IUUC-Smo-109363	Selaginella moellendorffii	53.94	0.00e+00	694.00
IUUC-Sit-109752	Setaria italica	54.12	0.00e+00	671.00
IUUC-Sly-110910	Solanum lycopersicum	56.34	0.00e+00	696.00
IUUC-Stu-112814	Solanum tuberosum	56.18	0.00e+00	693.00
IUUC-Sbi-113810	Sorghum bicolor	53.14	0.00e+00	659.00
IUUC-Sre-115168	Sporisorium reilianum	43.11	2.00e-179	622.00
IUUC-Ssc-115398	Sus scrofa	66.84	1.00e-146	513.00
IUUC-Tgu-117361	Taeniopygia guttata	65.01	0.00e+00	907.00
IUUC-Tsy-119587	Tarsius syrichta	68.62	0.00e+00	821.00
IUUC-Tni-119757	Tetraodon nigroviridis	64.39	0.00e+00	904.00
IUUC-Tca-121570	Theobroma cacao	56.58	0.00e+00	691.00
IUUC-Tre-122024	Trichoderma reesei	51.20	1.00e-168	587.00
IUUC-Tvi-122502	Trichoderma virens	50.64	4.00e-171	595.00
IUUC-Tae-125799	Triticum aestivum	53.20	0.00e+00	666.00
IUUC-Tme-127001	Tuber melanosporum	44.69	1.00e-133	469.00
IUUC-Ttr-129128	Tursiops truncatus	58.17	0.00e+00	762.00
IUUC-Uma-129588	Ustilago maydis	43.51	6.00e-179	621.00
IUUC-Vda-129990	Verticillium dahliae	48.62	6.00e-157	547.00
IUUC-Vvi-131611	Vitis vinifera	54.83	0.00e+00	695.00
IUUC-Xtr-132727	Xenopus tropicalis	63.95	0.00e+00	899.00
IUUC-Xma-133492	Xiphophorus maculatus	64.97	0.00e+00	910.00
IUUC-Yli-134358	Yarrowia lipolytica	49.85	4.00e-178	618.00
IUUC-Zma-135844	Zea mays	50.29	3.00e-174	605.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence