iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021948

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02051243

Gene Name

TRIM21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000012189.3	ENSCPOT00000012305.2	ENSCPOP00000010962.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-06	28.8	19	58

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl+ + + p++ +CgH f+++C+ ++      +++   CP+Cr
   Q: 19   CCICLDAMVE-PVSIDCGHSFCQECISQV-----GKNGGGVCPTCR 58
           ********99.***************999.....7889999****8 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

HHPMASSEPL AKMWEEVTCC ICLDAMVEPV SIDCGHSFCQ ECISQVGKNG GGVCPTCRRC 60
FLLKNVRPNW HIANVMDTLK QMNQDAEEKA PGERCVVHRE RLLLFCEKDG QALCWVCDQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACCATCCCA TGGCCTCATC AGAGCCCTTG GCAAAGATGT GGGAGGAGGT AACATGCTGT 60
ATCTGCCTGG ATGCCATGGT GGAACCTGTG AGCATTGACT GTGGTCACAG CTTCTGCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0090086--P:negative regulation of protein deubiquitination
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010508--P:positive regulation of autophagy
GO:0045787--P:positive regulation of cell cycle
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0046598--P:positive regulation of viral entry into host cell
GO:0051865--P:protein autoubiquitination
GO:0031648--P:protein destabilization
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0070206--P:protein trimerization
GO:0034341--P:response to interferon-gamma

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001896	Ailuropoda melanoleuca	70.30	0.00e+00	692.00
IUUC-Bta-013083	Bos taurus	63.80	9.00e-171	593.00
IUUC-Cja-019002	Callithrix jacchus	72.32	0.00e+00	682.00
IUUC-Cfa-020415	Canis familiaris	67.95	0.00e+00	666.00
IUUC-Csa-023135	Chlorocebus sabaeus	72.86	1.00e-178	619.00
IUUC-Cho-024493	Choloepus hoffmanni	61.27	2.00e-83	301.00
IUUC-Dno-030061	Dasypus novemcinctus	64.07	7.00e-178	617.00
IUUC-Ete-033168	Echinops telfairi	64.20	1.00e-152	532.00
IUUC-Eca-033578	Equus caballus	70.30	0.00e+00	668.00
IUUC-Eeu-034749	Erinaceus europaeus	52.43	7.00e-120	424.00
IUUC-Fca-035468	Felis catus	65.99	0.00e+00	630.00
IUUC-Gac-042272	Gasterosteus aculeatus	33.83	3.00e-71	262.00
IUUC-Ggo-045190	Gorilla gorilla	72.22	0.00e+00	643.00
IUUC-Hsa-046583	Homo sapiens	72.22	0.00e+00	647.00
IUUC-Itr-048632	Ictidomys tridecemlineatus	70.51	0.00e+00	649.00
IUUC-Lch-050117	Latimeria chalumnae	34.84	8.00e-74	270.00
IUUC-Loc-052206	Lepisosteus oculatus	33.83	5.00e-67	248.00
IUUC-Laf-053455	Loxodonta africana	67.56	1.00e-177	615.00
IUUC-Mcc-054609	Macaca mulatta	72.65	8.00e-178	616.00
IUUC-Mmr-061369	Microcebus murinus	67.95	1.00e-166	579.00
IUUC-Mmu-063166	Mus musculus	65.37	9.00e-174	602.00
IUUC-Mpu-066889	Mustela putorius furo	69.87	0.00e+00	689.00
IUUC-Mlu-067647	Myotis lucifugus	70.49	2.00e-180	624.00
IUUC-Nle-069567	Nomascus leucogenys	71.58	0.00e+00	642.00
IUUC-Opr-071178	Ochotona princeps	60.68	4.00e-162	564.00
IUUC-Oar-090413	Ovis aries	67.45	3.00e-177	614.00
IUUC-Ptr-091187	Pan troglodytes	72.22	0.00e+00	647.00
IUUC-Pan-092231	Papio anubis	72.86	3.00e-178	617.00
IUUC-Pab-098079	Pongo abelii	68.64	5.00e-126	443.00
IUUC-Pca-100639	Procavia capensis	64.17	4.00e-125	441.00
IUUC-Pva-102476	Pteropus vampyrus	68.16	0.00e+00	629.00
IUUC-Rno-105054	Rattus norvegicus	64.26	6.00e-157	546.00
IUUC-Sar-113204	Sorex araneus	66.95	3.00e-168	584.00
IUUC-Ssc-116291	Sus scrofa	68.09	0.00e+00	634.00
IUUC-Tsy-118803	Tarsius syrichta	69.79	2.00e-122	432.00
IUUC-Tbe-127337	Tupaia belangeri	55.26	2.00e-94	338.00
IUUC-Ttr-128914	Tursiops truncatus	67.31	2.00e-167	581.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence