iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000022818.3	ENSMMUT00000056049.1	ENSMMUP00000057115.1
ENSMMUG00000022818.3	ENSMMUT00000021188.3	ENSMMUP00000019814.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-08	35.8	331	378

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 331  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 378
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

PYHSPAERLV AEADEGGCSA ITGMGLCFRC LLFSFSGRSG PRIGPCRCWG GLCSSALRCG 60
WFSSWPPPSK SAIPICGGSR GARRVSRWPP PHWLEGRLVS PRPLSPLSTA TFGRGVMAVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGTCCTTCG TGGAATGTCC TTATCATTCC CCTGCGGAAC GATTGGTCGC TGAGGCGGAT 60
GAAGGCGGGT GTAGCGCAAT AACTGGCATG GGTCTGTGTT TCCGCTGTCT TCTTTTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	88.09	2.00e-98	351.00
IUUC-Apl-003910	Anas platyrhynchos	88.03	5.00e-96	343.00
IUUC-Aca-004874	Anolis carolinensis	86.81	1.00e-94	339.00
IUUC-Bta-013507	Bos taurus	87.18	5.00e-88	317.00
IUUC-Cja-018925	Callithrix jacchus	98.30	3.00e-108	384.00
IUUC-Cfa-020947	Canis familiaris	87.66	5.00e-97	347.00
IUUC-Cpo-022286	Cavia porcellus	71.74	2.00e-104	372.00
IUUC-Csa-023825	Chlorocebus sabaeus	98.72	2.00e-108	385.00
IUUC-Cho-024577	Choloepus hoffmanni	88.84	5.00e-96	343.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	6.00e-16	78.20
IUUC-Dre-028562	Danio rerio	54.70	4.00e-55	207.00
IUUC-Dno-029834	Dasypus novemcinctus	88.51	3.00e-98	351.00
IUUC-Dor-030315	Dipodomys ordii	63.30	5.00e-116	410.00
IUUC-Ete-032408	Echinops telfairi	64.10	2.00e-108	385.00
IUUC-Eca-034244	Equus caballus	87.61	4.00e-97	347.00
IUUC-Fca-035391	Felis catus	84.12	9.00e-90	322.00
IUUC-Fal-036838	Ficedula albicollis	87.23	1.00e-95	342.00
IUUC-Gmo-038748	Gadus morhua	51.07	4.00e-58	218.00
IUUC-Gga-040619	Gallus gallus	86.81	4.00e-95	340.00
IUUC-Gac-041996	Gasterosteus aculeatus	62.45	7.00e-73	266.00
IUUC-Ggo-045481	Gorilla gorilla	88.46	1.00e-172	598.00
IUUC-Hsa-046170	Homo sapiens	89.90	1.00e-172	598.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	90.17	7.00e-99	352.00
IUUC-Lch-050397	Latimeria chalumnae	83.83	1.00e-93	335.00
IUUC-Loc-052038	Lepisosteus oculatus	73.08	8.00e-77	280.00
IUUC-Laf-054126	Loxodonta africana	89.36	4.00e-99	354.00
IUUC-Meu-056248	Macropus eugenii	77.46	6.00e-96	343.00
IUUC-Mga-059217	Meleagris gallopavo	86.70	1.00e-93	336.00
IUUC-Mmr-061581	Microcebus murinus	88.94	7.00e-98	349.00
IUUC-Mdo-062452	Monodelphis domestica	87.66	2.00e-96	344.00
IUUC-Mmu-063412	Mus musculus	87.23	5.00e-96	343.00
IUUC-Mpu-066479	Mustela putorius furo	88.46	7.00e-98	350.00
IUUC-Mlu-067723	Myotis lucifugus	88.46	3.00e-97	347.00
IUUC-Nle-069122	Nomascus leucogenys	97.45	3.00e-107	381.00
IUUC-Opr-070835	Ochotona princeps	84.12	1.00e-82	299.00
IUUC-Ont-071524	Oreochromis niloticus	53.25	2.00e-59	222.00
IUUC-Oan-073023	Ornithorhynchus anatinus	86.81	5.00e-93	333.00
IUUC-Ocu-073779	Oryctolagus cuniculus	86.75	7.00e-89	319.00
IUUC-Ola-086891	Oryzias latipes	62.98	6.00e-75	273.00
IUUC-Oga-087954	Otolemur garnettii	88.09	3.00e-96	344.00
IUUC-Oar-090006	Ovis aries	86.38	2.00e-93	335.00
IUUC-Ptr-090589	Pan troglodytes	97.87	1.00e-107	382.00
IUUC-Pan-091896	Papio anubis	95.40	0.00e+00	697.00
IUUC-Psi-093266	Pelodiscus sinensis	87.66	2.00e-96	345.00
IUUC-Pma-094265	Petromyzon marinus	76.39	2.00e-32	130.00
IUUC-Pfo-096633	Poecilia formosa	52.38	5.00e-53	201.00
IUUC-Pab-098253	Pongo abelii	97.45	4.00e-107	380.00
IUUC-Pva-102753	Pteropus vampyrus	65.39	8.00e-101	360.00
IUUC-Rno-105964	Rattus norvegicus	86.75	3.00e-87	314.00
IUUC-Sha-107270	Sarcophilus harrisii	87.23	4.00e-95	340.00
IUUC-Tgu-116822	Taeniopygia guttata	88.51	6.00e-97	347.00
IUUC-Tru-118168	Takifugu rubripes	52.02	5.00e-55	207.00
IUUC-Tni-120100	Tetraodon nigroviridis	51.35	1.00e-51	196.00
IUUC-Tre-121950	Trichoderma reesei	64.29	3.00e-19	90.50
IUUC-Tvi-122341	Trichoderma virens	61.40	1.00e-15	75.50
IUUC-Ttr-128672	Tursiops truncatus	86.94	3.00e-97	347.00
IUUC-Xtr-132200	Xenopus tropicalis	80.43	1.00e-87	316.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence