iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025727

UUCD1 version

UUC-CiI-00384

Ensembl Protein ID

ENSCINP00000002393.3

UniProt Accession

F6SBC7; F6SBC7_CIOIN

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000001234.3	ENSCINT00000002393.3	ENSCINP00000002393.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	3.10e-163	544.6	1	515

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 82   vlrkifayldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesF 168
           ++r+if+ ldrtyv +++++ + ++L+ldl+r+++++   +++r    ll+li++eR+g+++dr ll+++ ++l +L     +iy++ F
   Q: 1    MIRCIFLVLDRTYVLQNSMLPSLWDLGLDLFRENVLSRehVRERCFFGLLNLIKRERSGDTIDRCLLRNLLSMLNDL-----HIYHTMF 84
           79**********************************9989*********************************6666.....9****** PP
   S: 169  EakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll.aelvallrdkktedls 256
           E++fl++t+e y+ e ++  ++ ev+eYl + e r+ ee + +  ++++st+++L+ +ve++li+kh e+ll ++l +l+ +++ +dl 
   Q: 85   EKRFLHETEESYSIEGSAKRSSMEVHEYLIHTERRISEERDLCLACMDHSTLKPLTLCVEEQLISKHTEALLsKGLSHLIVENRIDDLM 173
           ***********************************************************************999*************** PP
   S: 257  rmykLlsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlka 345
           r+ykL+s v++g++ l+ ++++h+k+ ++ ++ +  ++++   +V++ll+lk+kl+++v ++F++d kF++al++afe+ +nk+     
   Q: 174  RLYKLFSAVKDGIQSLCTHFNKHVKNVASLIVLDVSNDHT---MVQDLLDLKEKLSNIVTKCFSKDLKFVEALREAFESSINKR----Q 255
           *********************************9999999...*****************************************....4 PP
   S: 346  akspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskL 434
            k +El+A+y+Dq++++++k++te el+++ld+++++f++i++kdvFe++Ykk+LakRLl+gksas +aE+s+++kLk+ecg  ft kL
   Q: 256  NKPAELIAKYVDQRMKSGNKEATEVELDRTLDQIMMLFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGGMFTGKL 344
           5555************************************************************************************* PP
   S: 435  erMfqdlkvSedlnrqFkeekentees..esvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgrae 521
           e+Mf+d++ S++l++q++++ + ++e   +++++sv++L++g+Wpt++ +e v+LP++l k++++f+ fYl+khsgRkL++  +lg++ 
   Q: 345  EGMFNDISHSKELMAQYRQHVTTKKEGkvPNIDMSVNILTMGYWPTYPPME-VQLPSYLVKLQDSFKDFYLSKHSGRKLSFRASLGHCV 432
           ******************998777665448999****************99.************************************* PP
   S: 522  lkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
           lk ++k+g++elqVs+fQ++vLL++n+   +s+ ++k +t+++++eLrrtlqsL+++k+++l+k+p++k+++++d f +N+ef
   Q: 433  LKSKFKNGNKELQVSQFQALVLLLYNEATCFSFLQIKSDTQIEDSELRRTLQSLACGKARILTKSPKGKDVNDGDNFNLNTEF 515
           *********************************************************************************99 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MIRCIFLVLD RTYVLQNSML PSLWDLGLDL FRENVLSREH VRERCFFGLL NLIKRERSGD 60
TIDRCLLRNL LSMLNDLHIY HTMFEKRFLH ETEESYSIEG SAKRSSMEVH EYLIHTERRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATCCTCA TTTATACGAT ACAGCCTTGA AGAATTATAC AAAGCAGTTG AAAATCTATG 60
TTCTCATAAG ATAGCAAAAA ATCTCTATGG TCAGGTATCA AAAAAGTTTT TTATTCATAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000285	Aegilops tauschii	53.33	0.00e+00	659.00
IUUC-Aml-002062	Ailuropoda melanoleuca	62.76	0.00e+00	764.00
IUUC-Atr-002727	Amborella trichopoda	55.45	1.00e-176	612.00
IUUC-Apl-004157	Anas platyrhynchos	63.90	0.00e+00	775.00
IUUC-Aca-004430	Anolis carolinensis	63.74	0.00e+00	776.00
IUUC-Aly-006547	Arabidopsis lyrata	54.96	0.00e+00	632.00
IUUC-Ath-006748	Arabidopsis thaliana	54.96	1.00e-180	625.00
IUUC-Acl-008359	Aspergillus clavatus	36.50	2.00e-106	378.00
IUUC-Afl-008567	Aspergillus flavus	39.56	2.00e-118	418.00
IUUC-Afu-008833	Aspergillus fumigatus	38.95	3.00e-115	408.00
IUUC-Ani-009373	Aspergillus nidulans	39.35	3.00e-117	414.00
IUUC-Ang-009622	Aspergillus niger	39.66	8.00e-119	420.00
IUUC-Aor-010241	Aspergillus oryzae	39.78	5.00e-118	417.00
IUUC-Ate-010251	Aspergillus terreus	39.72	1.00e-119	422.00
IUUC-Ame-011580	Astyanax mexicanus	63.74	0.00e+00	770.00
IUUC-Bgr-012219	Blumeria graminis	38.61	2.00e-104	372.00
IUUC-Bta-013244	Bos taurus	62.76	0.00e+00	763.00
IUUC-Bci-013744	Botrytis cinerea	39.76	2.00e-108	385.00
IUUC-Bdi-014223	Brachypodium distachyon	53.50	0.00e+00	660.00
IUUC-Bol-016544	Brassica oleracea	54.96	0.00e+00	654.00
IUUC-Bra-017794	Brassica rapa	55.12	0.00e+00	656.00
IUUC-Cja-019861	Callithrix jacchus	62.54	0.00e+00	768.00
IUUC-Cfa-021009	Canis familiaris	62.21	0.00e+00	766.00
IUUC-Cpo-021928	Cavia porcellus	62.93	0.00e+00	766.00
IUUC-Cre-022739	Chlamydomonas reinhardtii	46.46	4.00e-139	487.00
IUUC-Csa-024139	Chlorocebus sabaeus	62.70	0.00e+00	769.00
IUUC-Cho-024899	Choloepus hoffmanni	64.43	0.00e+00	677.00
IUUC-Csv-026117	Ciona savignyi	79.36	0.00e+00	1094.00
IUUC-Cgl-026761	Colletotrichum gloeosporioides	40.54	4.00e-117	414.00
IUUC-Cne-027026	Cryptococcus neoformans	34.41	5.00e-81	294.00
IUUC-Cme-027355	Cyanidioschyzon merolae	31.53	1.00e-87	316.00
IUUC-Dre-027916	Danio rerio	63.25	0.00e+00	762.00
IUUC-Dno-028879	Dasypus novemcinctus	60.33	0.00e+00	749.00
IUUC-Dor-030698	Dipodomys ordii	62.21	0.00e+00	748.00
IUUC-Dse-031159	Dothistroma septosporum	39.55	2.00e-110	392.00
IUUC-Dme-031652	Drosophila melanogaster	58.31	0.00e+00	688.00
IUUC-Ete-033101	Echinops telfairi	58.14	0.00e+00	681.00
IUUC-Eca-033952	Equus caballus	62.76	0.00e+00	764.00
IUUC-Eeu-034767	Erinaceus europaeus	62.76	0.00e+00	763.00
IUUC-Fca-036333	Felis catus	62.05	0.00e+00	764.00
IUUC-Fal-037248	Ficedula albicollis	63.90	0.00e+00	776.00
IUUC-Fox-037854	Fusarium oxysporum	38.30	9.00e-106	376.00
IUUC-Fso-038138	Fusarium solani	37.61	2.00e-107	382.00
IUUC-Gmo-038754	Gadus morhua	62.82	0.00e+00	764.00
IUUC-Ggr-040003	Gaeumannomyces graminis	36.70	1.00e-93	336.00
IUUC-Gga-041002	Gallus gallus	63.90	0.00e+00	776.00
IUUC-Gac-041555	Gasterosteus aculeatus	62.72	0.00e+00	757.00
IUUC-Gma-043960	Glycine max	55.45	0.00e+00	671.00
IUUC-Ggo-045468	Gorilla gorilla	62.33	0.00e+00	716.00
IUUC-Hsa-045679	Homo sapiens	62.70	0.00e+00	770.00
IUUC-Itr-048365	Ictidomys tridecemlineatus	62.76	0.00e+00	764.00
IUUC-Lch-049858	Latimeria chalumnae	63.90	0.00e+00	786.00
IUUC-Lpe-051446	Leersia perrieri	53.98	0.00e+00	663.00
IUUC-Loc-052415	Lepisosteus oculatus	63.00	0.00e+00	755.00
IUUC-Lma-053080	Leptosphaeria maculans	38.41	4.00e-115	407.00
IUUC-Laf-053701	Loxodonta africana	62.76	0.00e+00	763.00
IUUC-Mcc-055168	Macaca mulatta	62.54	0.00e+00	767.00
IUUC-Mor-057102	Magnaporthe oryzae	36.49	7.00e-102	363.00
IUUC-Mpo-057342	Magnaporthe poae	36.56	7.00e-92	330.00
IUUC-Mtr-058660	Medicago truncatula	55.28	0.00e+00	646.00
IUUC-Mla-058936	Melampsora laricipopulina	39.10	2.00e-105	375.00
IUUC-Mga-059754	Meleagris gallopavo	63.90	0.00e+00	775.00
IUUC-Mvi-060455	Microbotryum violaceum	44.46	3.00e-137	481.00
IUUC-Mmr-061551	Microcebus murinus	63.36	0.00e+00	771.00
IUUC-Mdo-062215	Monodelphis domestica	62.87	0.00e+00	767.00
IUUC-Mmu-063402	Mus musculus	62.54	0.00e+00	766.00
IUUC-Mac-064443	Musa acuminata	53.91	0.00e+00	664.00
IUUC-Mpu-066383	Mustela putorius furo	62.54	0.00e+00	769.00
IUUC-Mlu-068213	Myotis lucifugus	62.76	0.00e+00	764.00
IUUC-Nfi-068363	Neosartorya fischeri	38.79	1.00e-113	402.00
IUUC-Ncr-068950	Neurospora crassa	37.85	2.00e-112	399.00
IUUC-Nle-069606	Nomascus leucogenys	62.70	0.00e+00	770.00
IUUC-Opr-070671	Ochotona princeps	47.98	3.00e-76	278.00
IUUC-Ont-071562	Oreochromis niloticus	61.73	0.00e+00	761.00
IUUC-Oan-073607	Ornithorhynchus anatinus	63.74	0.00e+00	775.00
IUUC-Ocu-074731	Oryctolagus cuniculus	62.54	0.00e+00	766.00
IUUC-Oba-075198	Oryza barthii	53.82	0.00e+00	662.00
IUUC-Obr-076095	Oryza brachyantha	53.66	0.00e+00	661.00
IUUC-Ogl-077032	Oryza glaberrima	53.82	0.00e+00	661.00
IUUC-Ogu-078051	Oryza glumaepatula	53.82	0.00e+00	662.00
IUUC-Oin-079399	Oryza indica	54.30	0.00e+00	647.00
IUUC-Olo-080988	Oryza longistaminata	52.88	0.00e+00	652.00
IUUC-Ome-081600	Oryza meridionalis	53.04	0.00e+00	653.00
IUUC-Oni-082623	Oryza nivara	53.04	0.00e+00	654.00
IUUC-Opu-083762	Oryza punctata	53.66	0.00e+00	659.00
IUUC-Oru-084499	Oryza rufipogon	53.82	0.00e+00	662.00
IUUC-Ola-087101	Oryzias latipes	61.89	0.00e+00	763.00
IUUC-Olu-087650	Ostreococcus lucimarinus	49.68	2.00e-163	567.00
IUUC-Oga-088416	Otolemur garnettii	62.76	0.00e+00	764.00
IUUC-Oar-090230	Ovis aries	62.76	0.00e+00	762.00
IUUC-Ptr-091177	Pan troglodytes	62.70	0.00e+00	770.00
IUUC-Pan-092191	Papio anubis	62.70	0.00e+00	768.00
IUUC-Psi-093773	Pelodiscus sinensis	63.90	0.00e+00	778.00
IUUC-Pma-094678	Petromyzon marinus	60.76	2.00e-157	548.00
IUUC-Pno-094946	Phaeosphaeria nodorum	38.53	3.00e-100	358.00
IUUC-Ppa-095688	Physcomitrella patens	56.10	0.00e+00	683.00
IUUC-Pfo-097037	Poecilia formosa	62.21	0.00e+00	763.00
IUUC-Pab-097622	Pongo abelii	62.38	0.00e+00	764.00
IUUC-Pca-100391	Procavia capensis	55.92	9.00e-178	615.00
IUUC-Ppe-101142	Prunus persica	54.80	0.00e+00	650.00
IUUC-Pva-102995	Pteropus vampyrus	63.17	0.00e+00	651.00
IUUC-Pgr-103334	Puccinia graminis	36.79	1.00e-95	343.00
IUUC-Ptt-103903	Puccinia triticina	39.27	2.00e-84	305.00
IUUC-Pte-104167	Pyrenophora teres	37.90	1.00e-110	392.00
IUUC-Pyt-104736	Pyrenophora triticirepentis	37.65	4.00e-110	390.00
IUUC-Rno-106119	Rattus norvegicus	62.76	0.00e+00	766.00
IUUC-Sha-106958	Sarcophilus harrisii	63.25	0.00e+00	769.00
IUUC-Sja-107940	Schizosaccharomyces japonicus	33.98	1.00e-102	366.00
IUUC-Spo-108109	Schizosaccharomyces pombe	35.22	1.00e-94	339.00
IUUC-Ssl-108537	Sclerotinia sclerotiorum	39.33	5.00e-107	380.00
IUUC-Smo-109313	Selaginella moellendorffii	54.47	0.00e+00	668.00
IUUC-Sit-110626	Setaria italica	53.50	0.00e+00	655.00
IUUC-Sly-111497	Solanum lycopersicum	56.10	0.00e+00	681.00
IUUC-Sar-113581	Sorex araneus	56.29	1.00e-162	565.00
IUUC-Sbi-113931	Sorghum bicolor	53.82	0.00e+00	659.00
IUUC-Sre-114943	Sporisorium reilianum	40.36	3.00e-114	404.00
IUUC-Ssc-116133	Sus scrofa	61.24	0.00e+00	738.00
IUUC-Tgu-116462	Taeniopygia guttata	63.90	0.00e+00	776.00
IUUC-Tru-118299	Takifugu rubripes	63.25	0.00e+00	763.00
IUUC-Tsy-119517	Tarsius syrichta	70.17	2.00e-148	518.00
IUUC-Tni-119798	Tetraodon nigroviridis	62.21	0.00e+00	757.00
IUUC-Tca-121626	Theobroma cacao	55.12	0.00e+00	665.00
IUUC-Tre-121907	Trichoderma reesei	39.58	1.00e-107	382.00
IUUC-Tvi-122568	Trichoderma virens	38.50	2.00e-107	382.00
IUUC-Tae-123442	Triticum aestivum	53.33	0.00e+00	660.00
IUUC-Tur-126032	Triticum urartu	53.33	0.00e+00	659.00
IUUC-Tme-127162	Tuber melanosporum	41.84	1.00e-118	419.00
IUUC-Tbe-127658	Tupaia belangeri	61.56	0.00e+00	745.00
IUUC-Ttr-129112	Tursiops truncatus	57.72	0.00e+00	671.00
IUUC-Uma-129531	Ustilago maydis	39.77	7.00e-97	347.00
IUUC-Vda-129701	Verticillium dahliae	39.27	5.00e-115	407.00
IUUC-Vpa-130217	Vicugna pacos	54.80	0.00e+00	630.00
IUUC-Vvi-131133	Vitis vinifera	55.28	0.00e+00	667.00
IUUC-Xtr-132724	Xenopus tropicalis	62.34	0.00e+00	760.00
IUUC-Xma-134149	Xiphophorus maculatus	63.09	0.00e+00	763.00
IUUC-Zma-135529	Zea mays	53.50	0.00e+00	659.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence