iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055168

UUCD1 version

UUC-MaM-00110

Ensembl Protein ID

ENSMMUP00000042221.1

UniProt Accession

A0A1D5Q2F9; A0A1D5Q2F9_MACMU

Genbank Protein ID

ENSMMUP00000042221

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03019079

Gene Name

CUL4A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000019297.3	ENSMMUT00000060210.1	ENSMMUP00000042221.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	2.70e-208	694.7	2	560

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 38   lYkklkevleefi.kqvkkkveesedeq.lLktynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeived..ikk 122
           lYk+l++++e+++ +q+   +e+s d+  +Lk++n++W+++++q+ ++r+if++ldrtyv +++++ ++++++l+l+r++i++d  +++
   Q: 2    LYKQLRQACEDHVqAQILPFREDSLDSVlFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIWDMGLELFRTHIISDkmVQS 90
           9************99************************************************************************** PP
   S: 123  rllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeera 211
           ++++ +l lie+eR+geavdr+ll+++  +l++L     ++yk+sFE kfle+t+ +y+ae ++++qe+ev eYl++v +rl+ee +r+
   Q: 91   KTIDGILLLIEHERSGEAVDRSLLRSLLGMLSDL-----QVYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRV 174
           ******************************9998.....9************************************************* PP
   S: 212  aryleestetkLlevvekeliakhlesll.aelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekekdpkk 299
            +yl++ t+++L+++vek+l+ +hl+++l ++l++ll++++  dl++my+L+srv+ g + ll++++++ik+ g+a+++++ek+kd   
   Q: 175  ITYLDHGTQKPLIACVEKQLLGEHLTAILqKGLDHLLDENRVPDLAQMYQLFSRVRGGQQALLQHWSEYIKTFGTAIVINPEKDKD--- 260
           ***************************9989*******************************************************... PP
   S: 300  yVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaaksp.EllAryiDqlLrksskglteeeleaqldkvllvfkyis 387
           +V++ll++k+k++++++ +F+++++F++ ++++fetf+nk+     +++p El+A+++D++Lr+++k++t+eele++ldk++++f++i+
   Q: 261  MVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKR-----PNKPaELIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFIH 344
           *****************************************.....66666************************************** PP
   S: 388  ekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeekenteesesvelsvlvLsagaW 476
           +kdvFe++Ykk+LakRLl+gksas +aE+s+++kLk+ecga+ftskLe+Mf+d+++S+d++ +Fk++++n+++s  ++l+v++L++g+W
   Q: 345  GKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQHMQNQSDSGPIDLTVNILTMGYW 433
           ***************************************************************************************** PP
   S: 477  ptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpe 565
           pt++ +e v+L++e+ k++e f++fYl khsgRkLqWq+tlg+a lkae+k+gk+e+qVs fQ++vLL+fn+ + +s+ee+k+at++++
   Q: 434  PTYTPME-VHLTPEMVKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIED 521
           ***9999.********************************************************************************* PP
   S: 566  eeLrrtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
           +eLrrtlqsL+++k++vl k+p++ke+e++d+f++N ef
   Q: 522  SELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEF 560
           ************************************998 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MLYKQLRQAC EDHVQAQILP FREDSLDSVL FLKKINTCWQ DHCRQMIMIR SIFLFLDRTY 60
VLQNSTLPSI WDMGLELFRT HIISDKMVQS KTIDGILLLI EHERSGEAVD RSLLRSLLGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGGAAGGG CAGCTTCTCG GCGCTCGTGG GCCGCACCAA CGGCCTCACC AAGCCCGCGG 60
CCCTGGCCGC CGCGCCCGCC AAGCCGGGGG GCGCGGGCGG CTCCAAGAAG CTGGTCATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001592	Ailuropoda melanoleuca	94.23	0.00e+00	1250.00
IUUC-Apl-003269	Anas platyrhynchos	92.55	0.00e+00	1234.00
IUUC-Bta-012355	Bos taurus	94.70	0.00e+00	1265.00
IUUC-Cja-019861	Callithrix jacchus	99.09	0.00e+00	1318.00
IUUC-Cfa-021009	Canis familiaris	95.44	0.00e+00	1275.00
IUUC-Cpo-021867	Cavia porcellus	95.74	0.00e+00	1278.00
IUUC-Csa-024139	Chlorocebus sabaeus	99.85	0.00e+00	1325.00
IUUC-Cho-024899	Choloepus hoffmanni	96.63	0.00e+00	1011.00
IUUC-Cin-025727	Ciona intestinalis	62.54	0.00e+00	767.00
IUUC-Dno-028879	Dasypus novemcinctus	87.93	0.00e+00	1186.00
IUUC-Dor-030698	Dipodomys ordii	95.74	0.00e+00	1264.00
IUUC-Ete-033101	Echinops telfairi	88.96	0.00e+00	1165.00
IUUC-Eca-033696	Equus caballus	94.58	0.00e+00	1259.00
IUUC-Fca-036333	Felis catus	94.23	0.00e+00	1258.00
IUUC-Hsa-045679	Homo sapiens	99.54	0.00e+00	1323.00
IUUC-Itr-048182	Ictidomys tridecemlineatus	95.29	0.00e+00	1274.00
IUUC-Laf-054100	Loxodonta africana	95.15	0.00e+00	1265.00
IUUC-Meu-056492	Macropus eugenii	81.92	3.00e-154	538.00
IUUC-Mmr-061551	Microcebus murinus	95.14	0.00e+00	1262.00
IUUC-Mmu-063402	Mus musculus	95.74	0.00e+00	1277.00
IUUC-Mpu-066383	Mustela putorius furo	94.54	0.00e+00	1257.00
IUUC-Mlu-067450	Myotis lucifugus	90.62	0.00e+00	1190.00
IUUC-Nle-069606	Nomascus leucogenys	99.39	0.00e+00	1323.00
IUUC-Opr-070671	Ochotona princeps	67.61	2.00e-114	406.00
IUUC-Ocu-074731	Oryctolagus cuniculus	96.05	0.00e+00	1283.00
IUUC-Oar-089346	Ovis aries	93.93	0.00e+00	1253.00
IUUC-Ptr-091177	Pan troglodytes	99.54	0.00e+00	1323.00
IUUC-Pan-092191	Papio anubis	99.24	0.00e+00	1318.00
IUUC-Pab-097622	Pongo abelii	98.94	0.00e+00	1315.00
IUUC-Pca-100391	Procavia capensis	84.30	0.00e+00	996.00
IUUC-Pgr-103334	Puccinia graminis	36.27	4.00e-106	379.00
IUUC-Rno-105829	Rattus norvegicus	95.59	0.00e+00	1274.00
IUUC-Sha-106762	Sarcophilus harrisii	93.79	0.00e+00	1208.00
IUUC-Sre-114943	Sporisorium reilianum	40.39	2.00e-131	462.00
IUUC-Ssc-116133	Sus scrofa	93.92	0.00e+00	1231.00
IUUC-Tre-121907	Trichoderma reesei	40.11	3.00e-123	436.00
IUUC-Ttr-128326	Tursiops truncatus	88.06	0.00e+00	1071.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence