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Tag Content
UUCD2 ID IUUC-Dno-029832
UUCD1 version UUC-DaN-00754
Ensembl Protein ID ENSDNOP00000018754.1
UniProt Accession C3PT76; C3PT76_DASNO
Genbank Protein ID ACQ63020.1
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID DP001109
Gene Name USP44; USP49
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDNOG00000036608.1 ENSDNOT00000032809.1 ENSDNOP00000018754.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 8.10e-98 328.1 271 674
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle..........kkkeklneenp..................................... 42
           tGl+NlgNtCYmNSvLQ+Ls++  +r+++l+                    +                                     
   Q: 271  TGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKldlnqwlavtA---------Sdktrsykhpavtdtiilmnecqekdigsvhsrypgls 350
           7******************************76655444431.........13345556678888999999999999999999999999 PP
   S: 43   .....................kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkke 110
                                +++  +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ lld+++ el   
   Q: 351  sglsggalksrkmeliqprepSSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQHEL--- 436
           99999999888888888877777777************************************************************... PP
   S: 111  knkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.......slqdcLe 192
                 e+++++  +l   +++k  k+  ++++++F+gql sq++cl+cdn+s++ epf+dlsl++p++ +++ +        ++++L+
   Q: 437  ------ETTGTRLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKdipsqpcLVTEMLA 519
           ......7788888999999************************************************9999887789999999****** PP
   S: 193  sftkeeelegenkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspee 270
           +ft++e leg+  y c++c++k++           a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c++++ 
   Q: 520  KFTETEALEGKI-YVCDHCNSKCRrfsskpvvlteAQKQLMICQLPQVLRLHLKRFRWSGR-NNREKIGVHVGFEEILTMEPYCCRESL 606
           *********965.*******999999999999999***********************998.7778********************998 PP
   S: 271  kqke..kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           k+ +  + +Y+L+avv+H+G +++sGHY+ay++n++g+ W++++Dsk + ++++ev++   ++aY+lfY++
   Q: 607  KSLRpeCFIYDLSAVVMHHGkGFGSGHYTAYCYNSEGGfWVHCNDSKLSMCTMDEVCK---AQAYILFYTQ 674
           8876779***************************9999********************...********98 PP
   
Organism Dasypus novemcinctus
Protein Sequence
(Fasta)
MLTMDKCKHV GQLQLAQDHS ILNPQKWHCV DCNTTESIWA CLSCSHVACG RYIEEHALKH 60
FQDSSHPVAL EVNEMYVFCY LCDDYVLNDN ATGDLKLLRS TLSAIKSQNY HCTTRSGRVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dno-029832|DUB,USP|Dasypus novemcinctus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCGCCGAGC GGCCGGGGCC CGCCGGGGCG CGGGGGTGGG GCCCGCCGCC GCGTCGCGAT 60
GACGTCACCG CCGGGCCGGG CCGCCGCCGC CGCCGCCGCC GCCGGACCGG GGGGCGGCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dno-029832|DUB,USP|Dasypus novemcinctus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0035616--P:histone H2B conserved C-terminal lysine deubiquitination
GO:0000398--P:mRNA splicing, via spliceosome
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001220 Ailuropoda melanoleuca 92.41 0.00e+00 1336.00
IUUC-Apl-003673 Anas platyrhynchos 74.75 0.00e+00 1052.00
IUUC-Aca-004434 Anolis carolinensis 71.91 0.00e+00 1028.00
IUUC-Ame-010986 Astyanax mexicanus 63.53 0.00e+00 877.00
IUUC-Bta-012774 Bos taurus 89.17 0.00e+00 1275.00
IUUC-Cja-019619 Callithrix jacchus 89.47 0.00e+00 1276.00
IUUC-Cfa-020957 Canis familiaris 91.14 0.00e+00 1330.00
IUUC-Csa-023177 Chlorocebus sabaeus 90.32 0.00e+00 1284.00
IUUC-Cho-024877 Choloepus hoffmanni 91.79 0.00e+00 878.00
IUUC-Cin-025587 Ciona intestinalis 48.74 5.00e-107 382.00
IUUC-Csv-025814 Ciona savignyi 45.28 6.00e-154 537.00
IUUC-Dre-027878 Danio rerio 64.24 0.00e+00 845.00
IUUC-Ete-032627 Echinops telfairi 87.22 0.00e+00 1253.00
IUUC-Eca-033863 Equus caballus 85.33 0.00e+00 1209.00
IUUC-Eeu-035225 Erinaceus europaeus 84.95 0.00e+00 1202.00
IUUC-Fca-036288 Felis catus 91.84 0.00e+00 1327.00
IUUC-Fal-037207 Ficedula albicollis 74.64 0.00e+00 1015.00
IUUC-Gga-040457 Gallus gallus 73.10 0.00e+00 1016.00
IUUC-Ggo-044926 Gorilla gorilla 90.17 0.00e+00 1276.00
IUUC-Hsa-046079 Homo sapiens 90.03 0.00e+00 1276.00
IUUC-Itr-048737 Ictidomys tridecemlineatus 91.42 0.00e+00 1296.00
IUUC-Lch-050260 Latimeria chalumnae 66.99 0.00e+00 929.00
IUUC-Loc-051981 Lepisosteus oculatus 76.69 0.00e+00 665.00
IUUC-Laf-054491 Loxodonta africana 89.83 0.00e+00 1224.00
IUUC-Mcc-055694 Macaca mulatta 90.18 0.00e+00 1280.00
IUUC-Mga-059523 Meleagris gallopavo 72.93 0.00e+00 1035.00
IUUC-Mmr-060885 Microcebus murinus 92.85 0.00e+00 1314.00
IUUC-Mdo-063018 Monodelphis domestica 79.60 0.00e+00 1114.00
IUUC-Mmu-064012 Mus musculus 79.89 0.00e+00 1095.00
IUUC-Mpu-066207 Mustela putorius furo 91.42 0.00e+00 1343.00
IUUC-Mlu-066929 Myotis lucifugus 87.65 0.00e+00 1189.00
IUUC-Nle-069313 Nomascus leucogenys 79.89 0.00e+00 1093.00
IUUC-Opr-070375 Ochotona princeps 81.32 0.00e+00 1120.00
IUUC-Ont-071637 Oreochromis niloticus 61.99 0.00e+00 852.00
IUUC-Oan-073030 Ornithorhynchus anatinus 77.59 0.00e+00 850.00
IUUC-Ocu-074836 Oryctolagus cuniculus 87.73 0.00e+00 1241.00
IUUC-Oga-088367 Otolemur garnettii 91.58 0.00e+00 1283.00
IUUC-Oar-089953 Ovis aries 91.01 0.00e+00 1317.00
IUUC-Ptr-090980 Pan troglodytes 90.03 0.00e+00 1279.00
IUUC-Pan-092748 Papio anubis 90.87 0.00e+00 1291.00
IUUC-Pab-098514 Pongo abelii 90.04 0.00e+00 1277.00
IUUC-Pva-102984 Pteropus vampyrus 90.86 0.00e+00 1268.00
IUUC-Rno-106019 Rattus norvegicus 79.69 0.00e+00 1137.00
IUUC-Sha-106965 Sarcophilus harrisii 78.51 0.00e+00 1108.00
IUUC-Ssc-115299 Sus scrofa 91.55 0.00e+00 1339.00
IUUC-Tgu-117160 Taeniopygia guttata 74.96 0.00e+00 1018.00
IUUC-Tru-118156 Takifugu rubripes 61.19 0.00e+00 836.00
IUUC-Tni-119733 Tetraodon nigroviridis 59.72 0.00e+00 839.00
IUUC-Tbe-128084 Tupaia belangeri 83.43 0.00e+00 1197.00
IUUC-Ttr-128928 Tursiops truncatus 92.12 0.00e+00 1329.00
IUUC-Vpa-130706 Vicugna pacos 91.83 0.00e+00 1325.00
IUUC-Xtr-132061 Xenopus tropicalis 70.88 0.00e+00 936.00
Created Date 25-Jun-2017

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