iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042595

UUCD1 version

UUC-GaA-01229

Ensembl Protein ID

ENSGACP00000001366.1

UniProt Accession

G3N7T2; G3N7T2_GASAC

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000001056.1	ENSGACT00000001365.1	ENSGACP00000001364.1
ENSGACG00000001056.1	ENSGACT00000001367.1	ENSGACP00000001366.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-100	337.0	263	666

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenp........................................... 42
           tGl+NlgNtCYmNS+LQ+Ls+++++re++l+    +++e l+++n+                                           
   Q: 263  TGLRNLGNTCYMNSILQVLSHLQKFRECFLTldlcETEELLAKTNNsqetkgvaggvvssantplsggplgrvgepgswnlapgkkest 351
           7******************************9998444444444446667889999999999999999999999999999999999999 PP
   S: 43   ..................kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknk 113
                             + ++ +l+++l++lf+ +w+++++ vsp ++l++++++ + f+gy+qqDaqEfl+ lld++++el      
   Q: 352  plspqaselvqpkeprcsTRQQMSLCHELHTLFRVMWSGRWSLVSPFAMLHSVWNLIPAFRGYDQQDAQEFLCELLDKVQQEL------ 434
           99999999998888888878888************************************************************...... PP
   S: 114  pkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke...........slqdcL 191
              ++e+++++    + ++k  k+  ++++++F+gql sq++cl+c+++s++ epf+dlsl++p++ ++ ++           +l+++L
   Q: 435  ---DTEGSKRRIVIPITKRKLSKQVLKVLNTIFHGQLLSQVTCLSCKHKSNTVEPFWDLSLEFPERYHSIHKgsgatayqrscTLTEML 520
           ...7888999999999**************************************************9887779**************** PP
   S: 192  esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke..kkkY 278
           ++ft+ e leg+  y c++c+ ++ea+k+l + +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c++ +  + +   ++Y
   Q: 521  SKFTEMEALEGSI-YACNHCNTLSEARKQLLIYRLPQVLRLHLKRFRWSGR-NHREKIGVHVAFDQVLNIKPYCCTGSGHSVHrgGYTY 607
           **********966.**********************************997.8889*****************9995554433679*** PP
   S: 279  eLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           +L+avv+H+G +++sGHY+ay++n++g+ W++++Ds+ ++++ eev++   ++aY+lfY++r
   Q: 608  DLSAVVMHHGkGFGSGHYTAYCYNTEGGfWVHCNDSEMKVCSVEEVCN---TQAYILFYTQR 666
           ************************9999********************...********985 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MDRCKHVGRL RLGHDHSILN PQKWHCVACS TTDSVWACLK CSHVACGHFM EEHSLKHFQE 60
SQHPLAMEVR ELDVFCFACG DYVLNDNAEG DLKLLRGALS TVRSPGRRSL RSSTGGECAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCGTT GTAAGCACGT GGGACGCCTC CGCCTGGGCC ACGACCATTC AATCCTAAAT 60
CCACAAAAAT GGCACTGTGT GGCCTGCAGC ACCACCGATT CCGTGTGGGC CTGCCTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001220	Ailuropoda melanoleuca	53.22	0.00e+00	716.00
IUUC-Apl-003658	Anas platyrhynchos	62.64	0.00e+00	804.00
IUUC-Aca-005278	Anolis carolinensis	62.70	0.00e+00	806.00
IUUC-Ame-011403	Astyanax mexicanus	70.54	0.00e+00	827.00
IUUC-Bta-012911	Bos taurus	67.68	2.00e-164	572.00
IUUC-Cja-019171	Callithrix jacchus	60.72	0.00e+00	759.00
IUUC-Cfa-020957	Canis familiaris	53.21	0.00e+00	719.00
IUUC-Cpo-022233	Cavia porcellus	68.81	9.00e-165	573.00
IUUC-Csa-023177	Chlorocebus sabaeus	53.93	0.00e+00	699.00
IUUC-Cho-025051	Choloepus hoffmanni	62.78	3.00e-125	442.00
IUUC-Cin-025587	Ciona intestinalis	47.78	2.00e-104	374.00
IUUC-Csv-025814	Ciona savignyi	39.89	7.00e-131	461.00
IUUC-Dre-027577	Danio rerio	69.24	0.00e+00	853.00
IUUC-Dno-029856	Dasypus novemcinctus	61.29	0.00e+00	745.00
IUUC-Ete-032627	Echinops telfairi	53.05	0.00e+00	704.00
IUUC-Eca-033851	Equus caballus	56.77	0.00e+00	677.00
IUUC-Eeu-035225	Erinaceus europaeus	50.00	0.00e+00	651.00
IUUC-Fca-036288	Felis catus	52.94	0.00e+00	711.00
IUUC-Fal-037290	Ficedula albicollis	62.61	0.00e+00	742.00
IUUC-Gmo-039249	Gadus morhua	94.81	6.00e-176	610.00
IUUC-Gga-040457	Gallus gallus	55.06	0.00e+00	710.00
IUUC-Ggo-044979	Gorilla gorilla	61.09	0.00e+00	747.00
IUUC-Hsa-046743	Homo sapiens	61.09	0.00e+00	749.00
IUUC-Itr-048251	Ictidomys tridecemlineatus	58.57	0.00e+00	724.00
IUUC-Lch-050294	Latimeria chalumnae	62.61	0.00e+00	778.00
IUUC-Loc-051961	Lepisosteus oculatus	74.29	0.00e+00	694.00
IUUC-Laf-054491	Loxodonta africana	53.49	0.00e+00	699.00
IUUC-Mcc-055048	Macaca mulatta	60.66	0.00e+00	746.00
IUUC-Meu-055971	Macropus eugenii	54.87	6.00e-78	285.00
IUUC-Mga-059523	Meleagris gallopavo	54.07	0.00e+00	714.00
IUUC-Mmr-060885	Microcebus murinus	54.05	0.00e+00	715.00
IUUC-Mdo-062073	Monodelphis domestica	62.50	0.00e+00	806.00
IUUC-Mmu-064095	Mus musculus	59.83	0.00e+00	755.00
IUUC-Mpu-066207	Mustela putorius furo	53.30	0.00e+00	719.00
IUUC-Mlu-067090	Myotis lucifugus	68.47	1.00e-166	580.00
IUUC-Nle-069486	Nomascus leucogenys	61.09	0.00e+00	749.00
IUUC-Opr-070563	Ochotona princeps	59.74	0.00e+00	747.00
IUUC-Ont-072103	Oreochromis niloticus	89.66	0.00e+00	1151.00
IUUC-Oan-073030	Ornithorhynchus anatinus	53.33	2.00e-158	552.00
IUUC-Ocu-074836	Oryctolagus cuniculus	53.37	0.00e+00	716.00
IUUC-Ola-086413	Oryzias latipes	78.14	0.00e+00	1023.00
IUUC-Oga-088862	Otolemur garnettii	60.09	0.00e+00	750.00
IUUC-Oar-089953	Ovis aries	53.86	0.00e+00	722.00
IUUC-Ptr-090980	Pan troglodytes	53.85	0.00e+00	699.00
IUUC-Pan-092363	Papio anubis	60.66	0.00e+00	744.00
IUUC-Psi-093353	Pelodiscus sinensis	62.55	0.00e+00	810.00
IUUC-Pfo-096413	Poecilia formosa	87.46	0.00e+00	1147.00
IUUC-Pab-098514	Pongo abelii	54.36	0.00e+00	704.00
IUUC-Pca-100449	Procavia capensis	61.10	0.00e+00	761.00
IUUC-Pva-102868	Pteropus vampyrus	69.52	2.00e-167	582.00
IUUC-Rno-105190	Rattus norvegicus	60.14	0.00e+00	759.00
IUUC-Sha-107337	Sarcophilus harrisii	63.09	0.00e+00	808.00
IUUC-Sar-113561	Sorex araneus	81.75	9.00e-62	230.00
IUUC-Ssc-115727	Sus scrofa	58.20	0.00e+00	715.00
IUUC-Tgu-117025	Taeniopygia guttata	57.91	0.00e+00	673.00
IUUC-Tru-117585	Takifugu rubripes	84.79	0.00e+00	1081.00
IUUC-Tsy-118814	Tarsius syrichta	60.03	0.00e+00	744.00
IUUC-Tni-120600	Tetraodon nigroviridis	83.04	0.00e+00	994.00
IUUC-Tbe-128084	Tupaia belangeri	50.91	0.00e+00	675.00
IUUC-Ttr-128928	Tursiops truncatus	52.92	0.00e+00	715.00
IUUC-Vpa-130706	Vicugna pacos	52.29	0.00e+00	712.00
IUUC-Xtr-132090	Xenopus tropicalis	62.55	0.00e+00	788.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence