iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003271

Ensembl Protein ID

ENSAPLP00000011498.1

UniProt Accession

R0LZS8; R0LZS8_ANAPL

Genbank Protein ID

EOB07335.1

Protein Name

V(D)J recombination-activating protein 1

Genbank Nucleotide ID

ADON01015942

Gene Name

RAG1; Anapl_09689

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000011756.1	ENSAPLT00000012227.1	ENSAPLP00000011498.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	77.10	0.00e+00	1679.00	IUUC-Hsa-045964
E3 activity/RING/RING	75.48	0.00e+00	1646.00	IUUC-Mmu-064297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MSLASQMDLP EEIQHPYTKF SEWKFKLFKV RPSEKTSSDN SQCINKDQAE EVASTDKGIM 60
LHKDEGVPRG EKILTQTDLM GNRQALGKDA NDMKIQDNTE HQNNLKQLCR ICGVSFKSDC 120

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Nucleotide Sequence
(Fasta)

ATGTCGTTAG CATCTCAAAT GGACCTGCCT GAAGAGATTC AGCATCCTTA TACAAAATTT 60
TCCGAATGGA AATTCAAGCT GTTTAAAGTG AGACCATCTG AAAAAACATC TTCTGATAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF00097--zf-C3HC4
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination

KEGG

apla:101802725

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001206	Ailuropoda melanoleuca	76.76	0.00e+00	1640.00
IUUC-Aca-004400	Anolis carolinensis	77.15	0.00e+00	1676.00
IUUC-Ame-011295	Astyanax mexicanus	59.12	0.00e+00	1219.00
IUUC-Bta-012421	Bos taurus	77.25	0.00e+00	1650.00
IUUC-Cja-019891	Callithrix jacchus	75.73	0.00e+00	1599.00
IUUC-Cfa-020740	Canis familiaris	71.29	0.00e+00	1541.00
IUUC-Cpo-021800	Cavia porcellus	75.94	0.00e+00	1565.00
IUUC-Csa-024203	Chlorocebus sabaeus	75.48	0.00e+00	1422.00
IUUC-Dre-028416	Danio rerio	59.32	0.00e+00	1215.00
IUUC-Dno-029101	Dasypus novemcinctus	76.50	0.00e+00	1620.00
IUUC-Eca-033385	Equus caballus	76.70	0.00e+00	1635.00
IUUC-Fca-036545	Felis catus	76.74	0.00e+00	1622.00
IUUC-Fal-037208	Ficedula albicollis	90.01	0.00e+00	1959.00
IUUC-Gmo-039622	Gadus morhua	54.99	0.00e+00	1154.00
IUUC-Gga-041182	Gallus gallus	92.99	0.00e+00	1974.00
IUUC-Gac-041682	Gasterosteus aculeatus	57.45	0.00e+00	1201.00
IUUC-Ggo-044510	Gorilla gorilla	77.10	0.00e+00	1630.00
IUUC-Hsa-045964	Homo sapiens	77.10	0.00e+00	1631.00
IUUC-Itr-048862	Ictidomys tridecemlineatus	76.89	0.00e+00	1616.00
IUUC-Lch-050041	Latimeria chalumnae	69.19	0.00e+00	1451.00
IUUC-Loc-052464	Lepisosteus oculatus	63.59	0.00e+00	1359.00
IUUC-Laf-053544	Loxodonta africana	77.49	0.00e+00	1637.00
IUUC-Mcc-054867	Macaca mulatta	76.64	0.00e+00	1619.00
IUUC-Meu-055986	Macropus eugenii	76.19	0.00e+00	1484.00
IUUC-Mga-059262	Meleagris gallopavo	92.23	0.00e+00	1971.00
IUUC-Mdo-062686	Monodelphis domestica	76.68	0.00e+00	1660.00
IUUC-Mmu-064297	Mus musculus	75.48	0.00e+00	1633.00
IUUC-Mpu-066027	Mustela putorius furo	76.30	0.00e+00	1608.00
IUUC-Mlu-067885	Myotis lucifugus	77.17	0.00e+00	1632.00
IUUC-Nle-070073	Nomascus leucogenys	76.81	0.00e+00	1622.00
IUUC-Ont-071400	Oreochromis niloticus	59.46	0.00e+00	1254.00
IUUC-Oan-072920	Ornithorhynchus anatinus	91.07	0.00e+00	756.00
IUUC-Ocu-074616	Oryctolagus cuniculus	75.84	0.00e+00	1604.00
IUUC-Ola-086828	Oryzias latipes	58.97	0.00e+00	1234.00
IUUC-Oga-088675	Otolemur garnettii	88.93	5.00e-149	519.00
IUUC-Oar-090380	Ovis aries	76.50	0.00e+00	1662.00
IUUC-Ptr-090648	Pan troglodytes	77.00	0.00e+00	1627.00
IUUC-Pan-092036	Papio anubis	76.62	0.00e+00	1618.00
IUUC-Psi-093130	Pelodiscus sinensis	84.53	0.00e+00	1855.00
IUUC-Pfo-097273	Poecilia formosa	59.37	0.00e+00	1226.00
IUUC-Pca-100134	Procavia capensis	72.95	0.00e+00	1536.00
IUUC-Rno-105632	Rattus norvegicus	75.61	0.00e+00	1634.00
IUUC-Sha-107238	Sarcophilus harrisii	75.88	0.00e+00	1645.00
IUUC-Sar-113591	Sorex araneus	67.12	0.00e+00	1407.00
IUUC-Ssc-115720	Sus scrofa	77.40	0.00e+00	1628.00
IUUC-Tgu-117030	Taeniopygia guttata	90.22	0.00e+00	1949.00
IUUC-Tru-117669	Takifugu rubripes	57.16	0.00e+00	1130.00
IUUC-Tsy-119578	Tarsius syrichta	73.96	0.00e+00	1576.00
IUUC-Tni-120073	Tetraodon nigroviridis	57.06	0.00e+00	1186.00
IUUC-Tbe-128029	Tupaia belangeri	65.08	0.00e+00	740.00
IUUC-Ttr-128677	Tursiops truncatus	86.27	0.00e+00	748.00
IUUC-Vpa-130346	Vicugna pacos	88.04	0.00e+00	837.00
IUUC-Xtr-132442	Xenopus tropicalis	88.66	3.00e-101	360.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence